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Pharmaceutical composition for treating male erectile dysfunction and application thereof

A technology of erectile dysfunction and composition, which is applied in the direction of drug combination, medical preparations containing active ingredients, diseases, etc., can solve the problems of adverse reactions, short action time, slow onset, etc., and achieve obvious therapeutic effect and effective The effect of long time and reduction of occurrence rate

Active Publication Date: 2015-06-17
NANJING ANGGU PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to solve the defects of adverse reactions and short acting time or slow onset of existing drugs for treating male erectile dysfunction, the present invention provides a drug for treating ED with fast onset, long acting time and fewer side effects

Method used

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  • Pharmaceutical composition for treating male erectile dysfunction and application thereof
  • Pharmaceutical composition for treating male erectile dysfunction and application thereof
  • Pharmaceutical composition for treating male erectile dysfunction and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 Avanafil ginkgolide tablet

[0019]

[0020]

[0021] Preparation process: Weigh the prescribed amount of avanafil, ginkgolide, starch, sodium alginate and low-substituted hydroxypropyl cellulose and mix evenly. Another appropriate amount of 60% ethanol is added to the mixed powder, mixed evenly to make a soft material, granulated through a 16-mesh sieve, and dried below 60°C. After drying, use an 18-mesh sieve to carry out granulation, sieve out the fine powder in the dry granules, mix with the sieved magnesium stearate, and then mix with the dry granules evenly, and press into tablets to obtain the product.

Embodiment 2

[0022] Embodiment 2 Avanafil ginkgolide tablet

[0023]

[0024] Preparation process: Weigh the prescribed amount of avanafil, ginkgolide, starch, dextrin and low-substituted hydroxypropyl cellulose and mix evenly. Another appropriate amount of 60% ethanol is added to the mixed powder, mixed evenly to make a soft material, granulated through a 16-mesh sieve, and dried below 60°C. After drying, use an 18-mesh sieve to carry out granulation, sieve out the fine powder in the dry granules, mix with the sieved magnesium stearate, and then mix with the dry granules evenly, and press into tablets to obtain the product.

Embodiment 3

[0025] Embodiment 3 avanafil ginkgolide capsules

[0026]

[0027] Preparation process: pass the main drug and auxiliary materials in the prescription through a 100-mesh sieve, weigh avanafil, ginkgolide, microcrystalline cellulose, lactose, and micropowder silica gel, mix them evenly, and fill capsules to obtain the product.

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Abstract

The invention relates to a pharmaceutical composition for treating male erectile dysfunction and application thereof and belongs to the field of medicines. The invention provides a pharmaceutical composition with active ingredients containing avanafil by aiming at overcoming the defects that an existing medicine for treating the male erectile dysfunction has adverse effects and is short in action time or slowness for taking effect. The pharmaceutical composition can be used for obviously shortening an erection latent period and obviously prolonging an ejaculation latent period and has a good treatment effect on neuropathic ED.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating male erectile dysfunction and its application, in particular to a pharmaceutical composition containing avanafil for treating male erectile dysfunction and its application, and belongs to the field of medicine. Background technique [0002] Erectile dysfunction (ED) refers to the persistent (more than 3 months) inability of a man to achieve or maintain a penile erection with sufficient hardness to complete satisfactory sexual intercourse under sexual stimulation. According to statistics, 52% of men aged 40 to 70 have different degrees of ED. It is estimated that by 2025, there will be 322 million men in the world with ED problems. However, erectile dysfunction often involves multiple systems throughout the body, and the etiology is complex, including vascular, neurological, endocrine, psychological, senile and other factors, so the clinical efficacy is not ideal. [0003] There are thr...

Claims

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Application Information

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IPC IPC(8): A61K31/506A61P15/10A61K31/365
Inventor 程浩
Owner NANJING ANGGU PHARMA TECH
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