Multifunctional fiber with pH discoloration property, antibacterial property and drug-releasing property and preparation method thereof

Abstract

The invention provides multifunctional fiber with a pH discoloration property, an antibacterial property and a drug-releasing property and a preparation method thereof. The preparation method is characterized by comprising the following steps: polyacrylonitrile powder is dried and dehydrated, and then is filtered and separated by a filter screen; curcumin, vitamin E, the polyacrylonitrile powder obtained by separation in the step 1 and a solvent are mixed; the obtained mixed liquid is stirred so that polyacrylonitrile is expanded; polyacrylonitrile is heated to be dissolved to obtain a spinning solution; the obtained spinning solution is subjected to de-foaming and wet spinning; and the obtained nascent fiber is subjected to drying densification and heat setting treatment, thus obtaining the multifunctional fiber with pH discoloration property, antibacterial property and drug-releasing property. With the method provided by the invention, the prepared fiber has the advantages of even coloring and excellent color fastness. The fiber has the weaving mechanical property and has the pH response discoloration property. Because of a low spinning temperature, drug activities of curcumin and vitamin E can be maintained, so that the fiber also has antibacterial and drug sustained-release functions.

Description

technical field [0001] The invention relates to a multifunctional fiber with pH discoloration, antibacterial properties and drug release properties and a preparation method thereof, and belongs to the cross field of biomedicine and material processing technology. Background technique [0002] The drug-loaded fiber can be prepared by adding specific drugs into the spinning solution and spinning by blending. The new drug-loaded fiber spinning solution can be liquid, suspension, emulsion and melt liquid, and the drug is dissolved or dispersed in the spinning solution matrix in a certain form. After spinning, the drug is stably dispersed in the fiber polymer system, instead of just adhering or adsorbing on the surface of the fiber, it is easier to achieve sustained release through polymer decomposition or fiber pore diffusion. In recent years, in the field of biomedical textiles, a variety of new drug-loaded fibers with special therapeutic functions and auxiliary therapeutic fu...

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to overcome the shortcomings of uneven impregnation, poor washability, and short-term effect in the production of pH color-changing fabrics by the existing traditional dyeing and surface finishing processes, and to provide a pH color-changing, antibacterial fabric. The multi-functional fiber with property of property and drug release and preparation method thereof, adds appropriate amount of curcumin and vitamin E into the spinning solution for wet spinning, not only makes the fiber obtain the performance of pH-responsive discoloration, but also retains curcumin due to the low spinning temperature And the drug activity of vitamin E, so that the fiber has the function of antibacterial and drug sustained release

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