Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Eutectic mixtures in personal care compositions

A eutectic mixture, personal care technology, applied in cosmetic formulations, cosmetic formulations, pharmaceutical formulations, etc., can solve problems such as damage to texture

Active Publication Date: 2015-09-16
UNILEVER IP HLDG BV
View PDF11 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such recrystallization can cause undesired gelling of such personal care products, disrupting their texture

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Eutectic mixtures in personal care compositions
  • Eutectic mixtures in personal care compositions
  • Eutectic mixtures in personal care compositions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0097] Using the ingredients in Table 1 and the amounts described in Tables 2A and 2B, a mixture of BMDM, IPM, and (if present) 12-HSA was prepared as follows.

[0098]The three components BMDM, IPM and 12-HSA were weighed and then mixed by grinding in a mortar and pestle until a homogeneous clear mixture was obtained.

[0099] Table 1. Composition of the ternary eutectic mixture

[0100] Element purity CAS# supplier Melting point (°C) 12-HSA 95% 106-14-9 Alfa Aesar 81.5 BMDM (Parsol 1789?) 99.5% 70356-09-1 DSM 84.8 IPM 99% 110-27-0 Sigma 8.9

[0101] The melting points of these mixtures were measured and the results are shown in Tables 2A and 2B. It is clearly shown that the particular mixture has a lower melting temperature. The lowest measured melting point of about 5.6°C was determined for eutectic compositions of BMDM, IPM and 12-HSA at a weight ratio of 1:9 and a 12-HSA concentration of 3.5 wt% (for the total weight o...

Embodiment 2

[0107] A personal care composition (A2) comprising a preformed mixture of butylmethoxydibenzoylmethane, isopropyl myristate and 12-hydroxystearic acid according to Table 3A was prepared using the following protocol:

[0108] 1. Prepare Phase A by mixing the ingredients and heating the mixture to 70°C to dissolve the ingredients.

[0109] 2. Prepare phase B by mixing sodium polyacrylate and 1,3-butanediol and adding it to phase A. Rinse the beaker with glycerin and decante the glycerin into phase A. Repeat the same operation with water.

[0110] 3. Prepare Phase C by mixing ingredients at 75°C with hand stirring until phase is clear.

[0111] 4. Prepare Phase D by mixing the ingredients of the eutectic mixture (ie, BMDM, IPM, and 12-HSA) in a mortar and pestle until a clear liquid is obtained. Add this liquid to phase C.

[0112] 5. Mix the ingredients of phases E and F separately and add to the mixture obtained after step 4) at 75 °C with manual stirring.

[0113] 6. Add ...

Embodiment 3

[0121] Personal care compositions according to Table 3B were prepared using the following protocol. In A1, butylmethoxydibenzoylmethane, isopropyl myristate, and 12-hydroxystearic acid were added separately (ie not added as a pre-made eutectic mixture). A3 contains butylmethoxydibenzoylmethane and 12-hydroxystearic acid, but no isopropyl myristate.

[0122] 1. Prepare Phase A by mixing the ingredients and heating the mixture to 70°C to dissolve the ingredients.

[0123] 2. Prepare phase B by mixing sodium polyacrylate and 1,3-butanediol and adding it to phase A. Rinse the beaker with glycerin and decant to phase A. Repeat the same operation with water.

[0124] 3. Prepare Phase C by mixing ingredients at 75°C with hand stirring until phase is clear. For Al, 12-HSA and isopropyl myristate were added one by one to the dispersion as the last ingredients. In A3, 12-HSA was added to the dispersion as the last ingredient, this phase did not contain isopropyl myristate.

[0125...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
melting pointaaaaaaaaaa
melting pointaaaaaaaaaa
melting pointaaaaaaaaaa
Login to View More

Abstract

The invention relates to active eutectic mixtures of butyl methoxydibenzoylmethane, isopropyl myristate and optionally 12-hydroxystearic acid, personal care products comprising such active eutectic mixtures, a method for preparing such personal care compositions and a method of applying to human skin such personal care compositions.

Description

field of invention [0001] The present invention relates to eutectic mixtures of butylmethoxydibenzoylmethane, isopropyl myristate, and optionally 12-hydroxystearic acid; and personal care compositions comprising such eutectic mixtures. Background of the invention [0002] 12-Hydroxystearic acid (hereinafter "12-HSA") is reported to have various beneficial cosmetic effects on the skin. It is a known PPAR-alpha (peroxisome proliferator-activated receptor alpha subtype) activator, skin lightening agent and sebum secretion inhibitor. See for example US 6,423,325 to Alaluf et al, US 6,713,051 to Mayes et al, WO 2006 / 056283 (Hindustan Lever), US 2009 / 0317341 to Madison, US 6,197,343 to Minami et al, US2004 / 0043044 by Granger et al. [0003] Therefore, cosmetic products containing 12-HSA are highly desirable. [0004] JP 09-048962 describes the use of 12-HSA or a salt thereof as an active ingredient of a coagulation inhibitor to inhibit coagulation of liquid cleansers or liquid ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/35A61K8/365A61K8/37
Inventor E.克霍斯德S.G.舒姆姚银芳张启清
Owner UNILEVER IP HLDG BV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com