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Extract for specific complexing and decorporation or cleaning of rare-earth metals in transition elements and extraction method of extract

A rare earth metal and transition element technology, applied in the field of complex excretion-promoting drug preparation, can solve the problems of large toxic and side effects, short effective action time, low anti-radiation titer, etc., and achieve the effects of small toxic and side effects and fast metabolism

Inactive Publication Date: 2015-09-30
CHINA INST FOR RADIATION PROTECTION
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Problems solved by technology

[0002] At present, there are more than 500 effective anti-radiation stimulating drugs tested on mice at home and abroad, but mainly sodium carbonate, quinine, amino acids and aminoalkylphosphinic acid complexing agents, these chemically synthesized drugs Mainly, the specificity of excretion-promoting elements is not strong, the toxic and side effects are too large, and the effective time of action is short. The main reason is that some chemical drugs have low anti-radiation potency after clinical trials.

Method used

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  • Extract for specific complexing and decorporation or cleaning of rare-earth metals in transition elements and extraction method of extract

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Embodiment Construction

[0020] The present invention will be described in detail below in conjunction with the accompanying drawings and implementation process.

[0021] The medicine to be protected in the present invention is a traditional Chinese medicine, and its main component is tropolone. Tropolone has a complexing effect on the rare earth metals technetium, ruthenium, rhodium, and palladium in the transition elements in the human body, and can be used as a drug for promoting excretion of the rare earth metals technetium, ruthenium, rhodium, and palladium in the transition elements in the human body. Irradiated wound cleansing medication.

[0022] Such as figure 1 As shown, the extraction process and extraction method of extracting monotropolone compound from Chinese herbal medicine are as follows:

[0023] (1) The heartwood of arborvitae or mahogany is pulverized with a pulverizer to prepare wood powder that passes through a 2mm sieve;

[0024] (2) Boil the wood powder with a weak alkaline ...

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Abstract

The invention relates to a preparation technology for complexing and decorporation medicines, in particular to an extract for specific complexing and decorporation or cleaning of rare-earth metals in transition elements and an extraction method of the extract. The method comprises the following steps: with oriental arborvitae of cupressaceae and redwood heartwood as extraction materials, leaching with alkalescent water or leaching with alcohol, and recovering the leaching solvent, wherein the extracted components comprise tropolone, resin and volatile essential oil. The extract can be applied to complexing and decorporation medicines or illuminated wound cleaning medicines for personnel who are contaminated by radioactive rare-earth metals in the transition elements and other metals such as ruthenium, rhodium and palladium, and can also be applied to a complexing agent for cleaning and recovering radioactive experimental sites.

Description

technical field [0001] The invention relates to the preparation technology of complexation-expelling drugs, in particular to an extract used for specific complexation-promoting or cleaning of rare earth metals in transition elements and an extraction method thereof. Background technique [0002] At present, there are more than 500 effective anti-radiation stimulating drugs tested on mice at home and abroad, but mainly sodium carbonate, quinine, amino acids and aminoalkylphosphinic acid complexing agents, these chemically synthesized drugs The main reason is that the specificity of excretion-promoting elements is not strong, the toxic and side effects are too large, and the effective time is short. The main reason is that some chemical drugs have low anti-radiation potency after clinical trials. The excretion-promoting drugs for transition elements are even less. The present invention utilizes tropolone, a chemical component extracted from natural medicines, to specifically c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/14A61P39/04A61P17/02A62D3/33A62D101/43
Inventor 高芬芳马跃峰安艳
Owner CHINA INST FOR RADIATION PROTECTION
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