A kind of composition and preparation method for childbirth containing procaine
A technology of procaine and composition, which is applied in the field of composition for delivery and its preparation, can solve problems such as hypersensitivity and anaphylaxis, methemoglobin disease, etc., to prolong the action time, prevent pneumonia, eliminate inhibitory effect
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Embodiment 1
[0036] Embodiment 1: a kind of composition that is used for childbirth containing procaine, its dosage form is injection, by procaine 30mg, epinephrine 0.03mg, fentanyl 0.01mg, atropine 0.2 in every 100 milliliters of injections mg, sodium chloride 1mg, hydrochloric acid 1mg and the balance of water for injection.
[0037] The above-mentioned preparation method of the composition for childbirth containing procaine, comprises the steps:
[0038] 1) Dissolve procaine, fentanyl, atropine, and sodium chloride in water for injection, and stir to dissolve;
[0039] 2) Add epinephrine into hydrochloric acid, stir to dissolve;
[0040] 3) Mix the liquid medicine in step 1) and 2) evenly, and add an appropriate amount of hydrochloric acid to adjust the pH value to 3;
[0041] 4) Add water for injection to the full amount of the liquid medicine in step 3), add medicinal charcoal, stir for 5 minutes, and let stand for 10 minutes. Filter through titanium rod filter 0.45µm, 0.22µm cartrid...
Embodiment 2
[0043] Embodiment 2: a kind of composition that is used for childbirth containing procaine, its dosage form is injection, by procaine 40mg, epinephrine 0.07mg, fentanyl 0.05mg, atropine 0.8 in every 100 milliliters of injections mg, sodium chloride 5mg, hydrochloric acid 10mg and the balance of water for injection.
[0044] The preparation method of the composition for childbirth containing procaine of the present invention comprises the steps:
[0045] 1) Dissolve procaine, fentanyl, atropine, and sodium chloride in water for injection, and stir to dissolve;
[0046] 2) Add epinephrine into hydrochloric acid, stir to dissolve;
[0047] 3) Mix the liquid medicine in step 1) and 2) evenly, and add an appropriate amount of hydrochloric acid to adjust the pH value to 5;
[0048] 4) Add water for injection to the full amount of the liquid medicine in step 3), add medicinal charcoal, stir for 10 minutes, and let stand for 20 minutes. Filter through titanium rod filter 0.45µm, 0....
Embodiment 3
[0050] Embodiment 3: a kind of composition that is used for childbirth containing procaine, its dosage form is injection, in every 100 milliliters of injections, by procaine 33mg, epinephrine 0.04mg, fentanyl 0.02mg, atropine 0.4 mg, sodium chloride 2mg, hydrochloric acid 4mg and the balance of water for injection.
[0051] The preparation method of the composition for childbirth containing procaine of the present invention may further comprise the steps:
[0052] 1) Dissolve procaine, fentanyl, atropine, and sodium chloride in water for injection, and stir to dissolve;
[0053] 2) Add epinephrine into hydrochloric acid, stir to dissolve;
[0054] 3) Mix the liquid medicine in step 1) and 2) evenly, and add an appropriate amount of hydrochloric acid to adjust the pH value to 4;
[0055] 4) Add water for injection to the full amount of the liquid medicine in step 3), add medicinal charcoal, stir for 7 minutes, and let stand for 13 minutes. Filter through titanium rod filter ...
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