Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A method for constructing segmental individualized three-dimensional scaffold material for human urethra

A three-dimensional stent, segmental technology, applied in the medical field, can solve the problems of difficult to achieve precise control of micro-scale structure regulation

Active Publication Date: 2018-04-10
SHANGHAI SIXTH PEOPLES HOSPITAL +1
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the former cannot really achieve the so-called individualized urethra standard on the macro scale, while the latter can achieve individualized simulation on the macro scale, but it is difficult to achieve the goal of precise control on the micro scale structural regulation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A method for constructing segmental individualized three-dimensional scaffold material for human urethra
  • A method for constructing segmental individualized three-dimensional scaffold material for human urethra
  • A method for constructing segmental individualized three-dimensional scaffold material for human urethra

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] In step 1.1, the patient to be tested is placed in a supine position, and the penis-scrotum area and the external urethral orifice area are disinfected.

[0052] Stretch the penis in a weak state, and inject 10ml of tetracaine mucilage from the outer opening of the urethra to block the outer opening of the urethra and prevent the glue from overflowing.

[0053] Step 1.2, using Toshiba Aplio500 ultrasonic diagnostic instrument, probe model PLT-1204MV (center frequency 14MHz). Place the ultrasound probe at the penis-scrotum junction to observe the condition of the urethral lumen.

[0054] If the ultrasound finds that the urethral lumen is not fully opened, or the opening is not satisfactory. You can continue to inject tetracaine glue until the inner diameter of the urethra is greater than 8mm. If repeated operations fail to further open the urethral lumen, it is determined that there is stricture in this segment of the urethra.

[0055] The dynamic scanning mode is use...

Embodiment 2

[0066] In step 1.1, the patient to be tested is placed in a supine position, and the perineal area and the external opening of the urethra are disinfected.

[0067] Stretch the penis in a weak state, and inject 10ml of tetracaine mucilage from the outer opening of the urethra to block the outer opening of the urethra and prevent the glue from overflowing.

[0068] Step 1.2, using Toshiba Aplio500 ultrasonic diagnostic instrument, probe model PLT-1204MV (center frequency 14MHz). Place the ultrasound probe in the perineum to observe the condition of the urethral lumen.

[0069] If the ultrasound finds that the urethral lumen is not fully opened, or the opening is not satisfactory. You can continue to inject additional saline until the inner diameter of the urethra is greater than 8mm. If repeated operations fail to further open the urethral lumen, it is determined that there is stricture in this segment of the urethra.

[0070] The dynamic scanning mode is used to scan the ur...

Embodiment 3

[0083] In step 1.1, the patient to be tested is placed in a supine position, and the penis-scrotum area and the external urethral orifice area are disinfected.

[0084] Stretch the penis in a weak state, and inject 10ml of tetracaine mucilage from the outer opening of the urethra to block the outer opening of the urethra and prevent the glue from overflowing.

[0085] Step 1.2, using Toshiba Aplio500 ultrasonic diagnostic instrument, probe model PLT-1204MV (center frequency 14MHz). Place the ultrasound probe at the penoscrotal junction. Observe the condition of the urethral lumen.

[0086] If the ultrasound finds that the urethral lumen is not fully opened, or the opening is not satisfactory. You can continue to inject tetracaine glue until the inner diameter of the urethra is greater than 8mm. If repeated operations fail to further open the urethral lumen, it is determined that there is stricture in this segment of the urethra.

[0087] The dynamic scanning mode is used t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

The invention discloses a method for constructing a segmental individualized human urethral three-dimensional scaffold material, which comprises using three-dimensional ultrasound technology to obtain the overall imaging information of the patient's thin-layer penis; using a manual outline method to screen out the overall imaging information to be constructed Image area: Use 3D technology to perform 3D reconstruction and processing of the image area to be constructed, import it into a 3D printer for printing, and prepare a urethral model, and then construct a material-fillable urethral model after the urethral model is reversed by a silica gel inversion process. Silicone model: the filling material is placed in the silicone model for reorganization, and a three-dimensional scaffold material of human urethra with individual characteristics is constructed. The solid model constructed by the technical solution of the present invention fits the physiological and anatomical position structure of the normal human urethra, conforms to the individual characteristics of the patient, and enables the constructed material to have the advantage of being adjustable in macroscopic and microscopic multi-scales.

Description

technical field [0001] The invention belongs to the field of medical technology, and relates to a method for constructing medical human tissue scaffold materials, in particular to a method for constructing segmental individualization using three-dimensional ultrasonic imaging tools, three-dimensional printing technology combined with inverted film technology and biological material preparation technology A method for three-dimensional scaffolding materials of the human urethra. Background technique [0002] In the past ten years, the attention paid to the treatment of urethral stricture in complicated cases is showing a trend of continuous heating up. Although the current clinical gold standard for urethral repair and replacement surgery is still to use various autologous tissues such as penile flap, buccal mucosa, tongue mucosa and even colonic mucosa for reconstruction. However, the introduction of the concept of tissue engineering in this field has caused more and more i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/24A61L27/22A61L27/20A61L27/18A61L27/56B33Y10/00
Inventor 冯超李喆吕向国陈磊胡兵陈仕艳徐月敏王华平
Owner SHANGHAI SIXTH PEOPLES HOSPITAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com