40 results about "Urethral stricture" patented technology

The invention relates to a male urethra dilater with an endoscope, which comprises a base, a straight mirror canal, a bent mirror canal, a dilatation head, an optical fiber socket, a water injection port and an image interface, the dilatation head is a solid and transparent cone the end of which is spherical; a lens, an image transmission bar, a light transmitting bundle and a aqueduct are arranged in the straight mirror canal and the bent mirror canal, and a light cone is arranged in the optical fiber socket. The male urethra dilater solves the technical problems that the existing male urethra dilater is restricted in use when male urethra is narrow and visibility of the entire urethra can not be reached, and has the advantages of simple operation, real-time observation, clear image and convenient use.

Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.

Embodiments of the present invention provide a method of treating a stricture in a nonvascular body lumen such as urethral strictures, benign prostatic hyperplasia (BPH) strictures, ureteral strictures, esophageal strictures, sinus strictures, and biliary tract strictures. Embodiments of the present invention provide a method for treating at least one of benign prostatic hyperplasia (BPH), prostate cancer, asthma, and chronic obstructive pulmonary disease (COPD). The method can include delivering, for example, via drug coated balloon catheters, anti-inflammatory and anti-proliferative drugs (e.g., rapamycin, paclitaxel, and their analogues) and one or more additives.

A suturing method for anastomosis of live bodies and training bodies joins a duct having perimeter positions defined according to clock hour positions to an opening in a bladder using an articulating laparoscopic device having a gripper at a distal end with open and closed positions for loading a suture needle in either a forehand or backhand direction. The gripper has a yaw motion including left and right positions and a roll motion either clockwise or counterclockwise. The open and closed positions, yaw motion, and roll motion are under manual control of a user through manual controls at a proximal end of the articulating laparoscopic device. The perimeter positions include a 12-o'clock position proximal to the user and a 6-o'clock position distal of the user. The method includes driving a suture at about the 6-o'clock position through the bladder and then the duct wherein the suture needle is loaded forehand, the yaw is in a left position, and the roll is clockwise. Orientations and directions are provided for other suturing positions.

The invention relates to the minimally invasive therapy technology and a minimally invasive therapy instrument, in particular to a method and instrument for forming a targeted balloon of a living body catheter cavity, namely a minimally invasive surgery method and instrument for carrying out targeted rear urethra balloon dilatation forming on the rear narrowed urethra of the male, wherein the rear narrowed urethra might be caused by the BPH, a tumor, an inflammation and the like. The targeted dilatation balloon dilatation catheter is provided with at least one targeted dilatation balloon, wherein one cavity is used for draining or conveying body liquid or gases and another cavity is used for filling a targeted catheter cavity dilatation balloon. At least a row of protrusions for targeted dilatation forming or a protrusion for targeted dilatation forming is arranged on the surface of the targeted dilatation balloon in the direction of the long axis. The protrusions or the protrusion for targeted dilatation forming aligns with a zone or a part, needing targeted dilatation forming, of the catheter cavity and expands in a certain manner, at a certain speed and under the certain pressure to form the balloon. Thus, the targeted dilatation forming protrusion or protrusions form selective partial high intensity of pressure and high shearing force on the targeted forming zone of the catheter cavity and targeted dilatation forming of the catheter cavity is achieved.

A suturing method for anastomosis of live bodies and training bodies joins a duct having perimeter positions defined according to clock hour positions to an opening in a bladder using an articulating laparoscopic device having a gripper at a distal end with open and closed positions for loading a suture needle in either a forehand or backhand direction. The gripper has a yaw motion including left and right positions and a roll motion either clockwise or counterclockwise. The open and closed positions, yaw motion, and roll motion are under manual control of a user through manual controls at a proximal end of the articulating laparoscopic device. The perimeter positions include a 12-o'clock position proximal to the user and a 6-o'clock position distal of the user. The method includes driving a suture at about the 6-o'clock position through the bladder and then the duct wherein the suture needle is loaded forehand, the yaw is in a left position, and the roll is clockwise. Orientations and directions are provided for other suturing positions.

Embodiments of the present invention provide a method for treatment of nonvascular body lumen strictures such as benign prostatic hyperplasia (BPH), urethral strictures, ureteral strictures, prostate cancer, esophageal strictures, sinus strictures, biliary tract strictures, asthma and chronic obstructive pulmonary disease (COPD). The method involves delivering, preferably via drug coated balloon catheters, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues) and one or more additives.

The invention discloses a catheter coated with rapamycin. The outer surface of part catheter is coated with catheter. It is used for preventing disease recurrence for urine injured patient or urethral stricture patient.

The invention discloses a urethra catheter for expansion of a urethral canal and a manufacturing method thereof. The manufacturing method comprises the following steps of; (1) preparing a urethra catheter; (2) preparing a positioning device; and (3) preparing an expansion device. The invention also discloses a produced manufactured in the above method. The method is simple and can be realized easily, and the cost is low. The urethra catheter has a delicate design and reasonable structure. After the urethra catheter inserted into the urethral canal, the positioning device and the expansion device in a narrow state can be tightly attached to the outer wall of the urethra catheter, the outside diameter of the urethra catheter can be reduced effectively, and pains of patients can be eased; the urethra catheter can be effectively positioned in the bladder by the positioning device to facilitate positioning and expansion operations of the expansion device for a part to be expanded, an intermittent inflation or liquid filling method is adopted during expansion, the urethral canal can be expanded, urethral stricture can be treated, mucosal ischemic necrosis can be avoided, the surgical safety and effectiveness can be improved greatly, and the large-scale promotion and application can be facilitated.

The invention discloses a urethral expander, which comprises a front urethral expander and a back urethral expander, wherein the front urethral expander consists of a hollow probe body and a handle arranged on the probe body; the back urethral expander comprises a sheath body; the back end of the sheath body is provided with an inner hole; the front end of the sheath body is provided with a guidehole; and a cup rim is arranged in the guide hole, and is communicated with the inner hole. When the urethral expander is in use, during expansion, the front urethral expander and the back urethral expander break through a narrow part of a urethra and are converged on the urethra, and the pointed end of the front urethral expander is clamped into the cup rim of the back urethral expander, so thaturethra expansion operation is completed. The invention has the advantages: the front urethral expander is put into a front urethra and the front end of the front urethral expander is clamped into the cup rim at the front end of the back urethral expander to form a semicircular structure, and the front and back urethral expanders are combined and connected into a whole, so that normal position ofthe urethral expander can be judged easily, and damage to the urethra and the formation of a false passage are avoided.

The invention discloses a urethral calibrator expander formed by a spherical probe (1), a connection rod (2) and an expansion tube (4) orderly connected from left to right. The right end of the connection rod (2) is covered with a tapered expanding device (3); the top of the tapered expanding device (3) faces the ball probe (1) and the bottom faces the expanding tube (4); the interior of the tapered expanding device (3) is in a hollow-bowl structure; the length of the tapered expanding device (3) is shorter than the connection rod (2); and the diameter of the bottom surface of the tapered expanding device (3) is greater than the diameter of a cross section of the connection rod (2). The narrow part of the urethral stricture can be effectively probed; the diameter and the length of the narrow part can be measured; relative reference information is provided for urethrostenosis surgery treatment and surgical method; meanwhile, pains of a patient and damage to the urethral stricture due to the exchange of various types of urethral calibrator expander can be reduced as possible as can; a material drawing performance for urethral stricture inflammatory excreta and stones can be met; and inspection and clinical treatment guide can be facilitated.

The urethral dilator comprises a dilator body, wherein the dilator body is a double-layer hollow structure body composed of a hard structure inner layer and an expandable and contractable flexible structure outer layer, wherein the inner layer is a pipe body structure with two ends communicated with each other, the outer layer front end is connected with the inner layer front end to form a blunt cone head for sealing, the outer layer rear end is provided with an injection port, and a semi-closed cavity is formed between the inner and outer layers. The inner layer of the rigid tube structure can not only ensure the shape of the expander, but also realize the insertion of the guide wire; the flexible outer layer is a semi-closed cavity, which can be filled with liquid or gas through the injection port at the rear end, so that the main structure of the expander can be expanded to achieve the purpose of expanding the narrow, and the expander can be expanded with different diameters withoutchanging the expander. The whole structure is simple, which solves the problem that the existing dilator cannot handle multi-segment urethral stricture.

The invention provides a urethral dilator used together with a urethral probe. The dilator completely closely covers the urethral probe; the back end of the dilator is provided with a urethral probe insertion port, the back part of the dilator is provided with an air inlet, the middle section of the dilator is provided with an aerating channel connected with the air inlet, and the front end of the dilator is provided with an air cell connected with the aerating channel. The urethral dilator can be used together with the urethral probe with a corresponding size, high-pressure gas or high-pressure liquid can be charged in the inflatable air cell on the premise of detecting the narrow position of the urinary tract by the hard urethral probe to apply the horizontally acting force generated by the expansion of the air cell to the narrow position of the urinary tract, so that the urethral false passage caused when surrounding tissues are much easily damaged as the urethral probe is commonly forced to dilate the narrow position of the urinary tract is effectively avoided, and the effect of dilating the narrow position of the urinary tract is improved. The urethral dilator can be used together with the conventional urethral probe and conveniently produced and used, so that by using the urethral dilator, the occurrence of the iatrogenic urethral false passage is greatly lowered, and the pains in patients are relieved.

The invention relates to an ultrasonic controlled release prostate dilatation drug-delivery balloon system. The system comprises a balloon catheter, a dilatation balloon and an ultrasound probe. The dilatation balloon catheter has a four-chamber structure, and three chambers are used for balloon filling and the other chamber for drainage of urine. The compliant balloons at both ends are located atthe lower end of the bladder and urethra to secure the dilatation balloon system and reduce damage from displacement and friction. The drug-loaded balloon is used for dilatation of the narrow urethra, and the surface is designed with a spiral shape, a zigzag shape, a wave shape, and the like, and a specific surface area is increased to increase the drug loading. Drug loading can be realized through the microcapsules with different particle sizes, microcapsules can be stimulated by ultrasound with a certain intensity and frequency to release into the urethra mucosa and prostate to treat urethral stricture caused by prostatic hyperplasia. The small ultrasound probe can be used in vitro or in the rectum. The real-time contrast during the catheterization process accurately identifies the urethral stricture, so that the dilatation process is more intuitive and accurate. The ultrasonic probe can also control the intensity, frequency and time of the ultrasonic wave in real time, so that thedrug-loaded microcapsules on the surface of the dilatation drug-delivery balloon can be released at the target position, and the drug utilization rate and therapeutic effect are obtained.

A stenosis dilatation catheter is provided, including a catheter, a stenosis dilator is movably provided in the urine passage of the catheter, the stenosis dilation guide includes a tubular stenosis dilation guide body, at that front end of the narrow expansion guide body, the rear end of the guide portion is provided with an air bag, a through hole is arranged on the side wall of the narrow expansion guide inside the air bag, the posterior end of the stenosis dilation guide body is provided with an elastic bag body, the elastic bag body and the stenosis dilation guide body form a sealed spacefilled with gas or liquid inside, the front end of the urine passage is provided with an opening, the guide portion and the air sac are arranged outside the front end of the urine catheter through the opening of the front end of the urine catheter, and the elastic bag body is arranged outside the urine cavity. As that urethral stricture occur, the urethral stricture dilator is moved forward, thenthe elastic bag body is squeeze, the balloon is propped up, the urethral side wall is distracted, the urethral catheter continues to advance, the elastic bag body is loosened, and the operation is repeated, so that the urethral catheter is easy to be inserted.

The present invention is one rear urethral probe and one puncture needle for treating urethral stricture and urethral atresia. The rear urethral probe includes one sheath, one arc segment and one front straight segment connected successively, and has smooth hole. The puncture needle fitting the said rear urethral probe includes one needle with threads in the front part. During cryoprobe treatment of urethral stricture and urethral atresia, the puncture needle is first used in searching the weakest part, and the rear urethral probe is then used in puncturing. The present invention can facilitate the operation of treating urethral stricture and urethral atresia.

The invention discloses an olecranon type urethral dilator with an openable sheath. The olecranon type urethral dilator comprises a dilator body, a high-pressure ball capsule and the openable sheath. The upper end of the dilator body is provided with a finger pulp groove. The lower end of the dilator body is provided with an olecranon type bend. A guide-in hole penetrating through the two ends of the dilator body is formed in the dilator body. The high-pressure ball capsule is arranged on the dilator body and located on the upper portion of the olecranon type bend. The included angle between the tangential direction of the olecranon type bend and the length direction of the dilator body is 30-45 degrees. The openable sheath is arranged outside the dilator body. The olecranon type urethral dilator is provided with the openable sheath, the dilator body can be guided by a guide wire in the guide-in hole in the dilator body when placed in, the openable sheath can be placed into the bladder under the guide of the dilator body after the urethra is sequentially dilated, and a catheter is easily guided into the bladder. Operation is easy and convenient, hemorrhage during operation, injuries and other complications can be reduced, and urethral stricture surgery treatment difficulty and errors are reduced.

In clinical practice, the procedure of urinary catheterization may cause severe irritation to urethra and bladder. In addition, physiological and pathological stricture and curvature of human urethra will increase the difficulty of urinary catheterization and aggravate the injury of lower urinary tract during insertion. The injury of lower urinary tract may induce or aggravate lower urinary tract infection and further affect the lower urinary tract or even the systemic organ function. At present, clinical solutions to urethral stricture comprise: The use of a stronger tip or metal probe or guide wire increases the external force to push forward, resulting in severe contusion of the urethra intima and susceptibility to infection; another method is to coat the outer surface of the urinary catheter with lubricating oil or lubricant coating, but using it alone is almost ineffective for urethral stricture. The utility model provides a stricture-dilated urinary catheter, which can be used for filling the dilatable part of the catheter tip thin segment in a targeted manner during the insertion, and with the uniform coating of lubricating substances, thereby improve the success rate of the insertion and minimize the risk of injury and infection.

The invention provides a multistage urethral stricture dilatation type drainage tube with balloons. The multistage urethral stricture dilatation type drainage tube comprises drainage tubes and a support tube, wherein the drainage tubes include a drainage tube I, a drainage tube II, a drainage tube III and a drainage tube IV; the drainage tube I is internally provided with a channel I; the drainagetube II is attached to a head end balloon, and a channel II and a channel III are arranged inside the drainage tube II; a channel IV, a channel V, a channel VI, a channel VII and a channel VIII are arranged in the drainage tube III; the outer wall of the drainage tube III is sleeved with a balloon I, a balloon II and a balloon III; a channel IX, a channel X, a channel XI, a channel XII and a channel XIII are arranged in the drainage tube IV; a connector I, a connector II, a connector III, a connector IV and a connector V are arranged on the drainage tube IV; the tail end of the support tube is connected with the connector V; and the support tube is inserted into a channel in the connector V and penetrates out of the channel I. By adopting the scheme for urethral stricture dilatation and urination, the stricture dilatation range can be expanded, the replacement frequency of the drainage tube can be reduced, and the disease course can be shortened.

The invention discloses a fixator for promoting healing of urethral wounds and anastomotic stomas between a urethra and a bladder neck. The fixator comprises short trousers, a baseplate adhering to the front sides of the short trousers, elastic binding ropes which are connected between the short trousers and the baseplate, rams which are hinged to the front side of the baseplate, a catheter clamping buckle which is fixed to the front ends of the rams and a catheter which backward penetrates from the catheter clamping buckle. After operations, such as radical prostatectomy, electrovaporization of the prostate, urethral reunion operation, bladder cancer radical surgery (orthotopic neobladder) and urethral stricture operation, and when the urethra is injured to bleeding and the catheter needs to be pulled outwards, the fixator is used so that the connection between two broken ends of the urethra or the anastomotic stomas between the urethra and the bladder neck can be tighter, the wounds or the anastomotic stomas can be tighter, bleeding is reduced, and the fixator promotes healing of the wounds or the anastomotic stomas and can also be used for oppressing the urethra to stop bleeding by pulling the catheter when the urethra is injured.

The invention discloses a urethral catheter applicable to women. The urethral catheter comprises a hollow body pipeline made from a solid material provided with an inner surface and an outer surface and also comprises a guiding protective part which can make at least the portions, located in the urinary bladder and the urethra, of the urethral catheter during indwelling arranged in the part in a sleeved mode in use and a urethral catheter driving part in sleeved connection with a cylindrical body of the guiding protective part and provided with a rod-like body, wherein the body of the urethral catheter is a cylindrical. The shortcoming of traditional 'guide-free suspended indwelling' is eliminated in the safety mode of 'guided approaching and indwelling', the contamination of surrounding tissue of the external urethral orifice to the urethral catheter is thoroughly avoided, and the urethral inner membrane damage caused by urethrostenosis in the indwelling process can be avoided to the most degree.

The invention discloses a catheter for urethra dilation and a production method for the same and belongs to the technical field of medical appliances. The method comprises the steps of (1) preparation of the catheter, (2) preparation of a positioning device and (3) preparation of a dilation device. The invention also discloses the catheter for the urethra dilation. The method provided by the invention is simple, can be implemented easily and is low in cost. The product provided by the invention has clever design and a rational structure. When the catheter is inserted into a urethra, the positioning device and the dilation device are shrunk and can thus be closely adhered to the outer wall of the catheter, so that an outer diameter of the catheter is effectively reduced and a patient's pain can be relieved; by the positioning device, the catheter can be effectively positioned in a bladder, so that the dilation device can easily carry out positioning and dilation actions to parts in need of dilation; during the dilation, intermittent gas inflation or liquid filling is adopted, so that the urethra dilation and a urethral stricture treatment can be implemented; safety and effectiveness of operations are greatly enhanced; and extensive generation and application can be implemented.

The invention discloses a visual electronic mirror urethral dilator and an application method thereof. The visual electronic mirror urethral dilator includes a display screen, a metal mirror pin, a saccule and a visual urethroscope. The front end of the metal mirror pin is connected to the display screen, and a saccule pressurization hole and a water flushing hole are disposed on both sides of thefront end of the metal mirror pin; The diameter of the saccule is 4.5 mm, the inside of the saccule is provided with a hole having a diameter of 2 mm, the tail end of the metal mirror pin passes through the hole and extends out of the saccule, and the saccule communicates with the saccule pressurization hole; and the visual urethroscope is disposed on the tail end of the metal mirror pin, and thevisual urethoscope is connected to the display screen through a conducting wire. The visual electronic mirror urethral dilator is simple in structure, is reasonable in design, can guide the dilator saccule to pass through a urethra narrow section under supervision of a display device, and gradually pressurizes the dilator saccule to make the urethra narrow section incarceratedly dilate, and so, damage is small, bleeding is less, dilatation is complete, a false passage does not occur, and surrounding visceral organs are not damaged. The visual electronic mirror urethral dilator is simple and easy to learn, is easy for beginners to master and is safe to operate, and complications of urethral dilation are reduced.

The invention discloses a urethral dilator for urethral stricture and a use method of the urethral dilator. The urethral dilator for urethral stricture comprises a urethral probe, a medical metal guide wire, a fascia dilator, a thin sheath and a urinary catheter, the urethral probe is a hollow metal catheter, one end of the urethral probe is inclined upwards, a wire outlet is formed in the upper side of one inclined end of the urethral probe, the thin sheath is in sleeve connection with the fascia dilator with the corresponding model, one end of the thin sheath is provided with an outward turning portion sleeving the surface of the thin sheath, the outward turning portion is torn from the middle to two sides, and the outer diameter of the urinary catheter is smaller than the inner diameterof the thin sheath. The urethral dilator solves the problems that in practical application, the operative treatment period of urethral stricture is long, a patient has to withstand great pain withina period of time, and medical cost is high.

Glycerophosphate salts have been found to drastically improve the treatment of urogenital disorders such as urethral strictures and vaginal atrophy. Methods, devices and kits are described for treating urogenital disorders using a composition comprising an effective amount of a glycerophosphate salt.

The invention discloses a new use of chloroquine or a pharmaceutically acceptable salt thereof, wherein the new use is a use of chloroquine or the pharmaceutically acceptable salt thereof in preparation of a drug for treating and / or alleviating overactive bladder. The chloroquine can be commercialized chloroquine, the chloroquine pharmaceutically acceptable salt can be a chloroquine pharmaceutically acceptable water-soluble salt, and in addition, the drug with the chloroquine as an active ingredient can also be used for treating and / or alleviating overactive bladder. Experiments find out that the chloroquine can significantly improve abnormal urination caused by urethral obstruction, can significantly delay the abnormal bladder form caused by urethral obstruction and can be used for treating and / or alleviating overactive bladder caused by urethral stricture.

The invention discloses a false-path-free urethrostenosis orientation plasma electric knife. The electric knife comprises a cutting electrode, a circuit electrode and a conducting wire pipe, wherein a ceramic insulation pipe is arranged between the cutting electrode and the circuit electrode, an arc ceramic protection sleeve is arranged on one end of the ceramic insulation pipe, and the arc ceramic protection sleeve covers one side of the cutting electrode. The cutting electrode is insulated to normal tissues in the urethra of the human body to form an electrode orientation working surface, the damage of the cutting electrode on the normal tissue can be effectively avoided, the electric knife can more smoothly reach the focus tissue of the disease, a false path is prevented from forming in the urethra, and the risk of recurrence urethrostenosis can be lowered.