Drug for treating internal hemorrhoid due to damp-heat pouring downward syndrome

A damp-heat injection type and drug technology, applied in the field of traditional Chinese medicine, can solve problems such as not suitable for large-scale promotion, only suitable for external hemorrhoids, high risk, etc., and achieve the effect of improving bleeding time, relieving pain, and excellent comprehensive evaluation of curative effect

Inactive Publication Date: 2016-01-13
庄小侃
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Laser surgery is a more thorough treatment, but it is costly and risky, and it is only suitable for external hemorrhoids, and it is not suitable for large-scale promotion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0076] The present invention also provides a preparation method when the above-mentioned medicine is prepared into a suppository, which includes:

[0077] The first step is to take each of the raw materials and pulverize them into powders, mix them together, add water to extract 2 to 4 times, the amount of water added each time is 3 to 5 times the sum of the quality of the raw materials, and the extraction solution each time Merge, concentrate and filter the extract, the first extract with a relative density of 1.35 at 80°C, and the dregs for later use;

[0078] In the second step, the dregs of the first step are soaked in 60-90% ethanol with an alcohol concentration of 60-90% for 1 hour, extracted twice, each time for 2-4 hours, and the amount of ethanol added each time is 3-3% of the sum of the quality of each crude drug. 5 times, each combined extract, 80-160 mesh filtration, 6000-10000 rpm centrifugation, supernatant, ultrafiltration through an ultrafiltration column with ...

Embodiment 1

[0082] Embodiment 1 suppository 1

[0083] Take fried Scutellaria baicalensis 15g, Pulsatilla 15g, Coptis 20g, Phellodendron 20g, Qinpi 15g, raw rhubarb 15g, betel nut 15g, donkey-hide gelatin 15g, yanhusuo 15g, red peony 15g, fried Sophora japonica 10g, Nepeta charcoal 10g, Burnet charcoal 10g, Poria cocos 25g, 20g of Panax notoginseng powder, 20g of angelica, 10g of peach kernel, 20g of turmeric, 15g of gallnut, 10g of frankincense, 20g of myrrh, and 15g of raw licorice, respectively crushed into powder, mixed together, adding 1.5kg of water each time, extracting 3 time, each time the extracts are combined, the extracts are concentrated and filtered, the first extract with a relative density of 1.35 at 80°C, the dregs are soaked in 80% ethanol for 1 hour, and extracted twice, each time for 3 hours , the amount of ethanol added each time is 1.5kg, and each combined extract is filtered at 80-160 mesh, centrifuged at 10,000 rpm, and the supernatant is taken, and the ultrafiltra...

Embodiment 2

[0085] Embodiment 2 suppository 2

[0086] Take fried Scutellaria baicalensis 15g, Pulsatilla 15g, Coptis 15g, Phellodendron 20g, Qinpi 10g, raw rhubarb 15g, betel nut 10g, donkey-hide gelatin 15g, Corydalis 10g, red peony 15g, fried Sophora japonica 10g, Nepeta charcoal 10g, Burnet charcoal 10g, Poria cocos 20g, 15g of Panax notoginseng powder, 15g of angelica, 10g of peach kernel, 15g of turmeric, 15g of gallnut, 10g of frankincense, 15g of myrrh, and 15g of raw licorice, respectively crushed into powder, mixed together, adding 1.5kg of water each time, extracting 3 time, each time the extracts are combined, the extracts are concentrated and filtered, the first extract with a relative density of 1.35 at 80°C, the dregs are soaked in 80% ethanol for 1 hour, and extracted twice, each time for 3 hours , the amount of ethanol added each time is 1.5kg, and each combined extract is filtered at 80-160 mesh, centrifuged at 10,000 rpm, and the supernatant is taken, and the ultrafiltr...

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Abstract

The invention provides a drug for treating internal hemorrhoid due to damp-heat pouring downward syndrome. The drug is characterized by being prepared from crude drugs including scutellaria baicalensis, Chinese pulsatilla roots, coptis chinensis, cortex phellodendri, ash barks, raw rhubarb, areca nuts, donkey-hide gelatin, rhizoma corydalis, red paeony roots, fried flos sophorae, carbonized catnip, carbonized sanguisorba roots, tuckahoe, pseudo-ginseng powder, angelica sinensis, peach kernels, radix curcumae, Chinese galls, olibanum, myrrh and raw liquorice. The drug has the favorable curative effects of clearing away heat and dispelling wind, cooling blood for hemostasis as well as relieving swelling and pain; modern pharmacological researches prove that the drug has the remarkable effects of shortening the bleeding time, relieving pain and reducing inflammatory reaction effects through animal experiments; acute and long-term toxicological researches prove that the drug is safe and free of obvious toxic or side effect; and clinical researches prove that the comprehensive assessment for the curative effect of the drug is superior to that of a positive control drug of a traditional Chinese medicine, which sufficiently shows the advantage of the drug.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating damp-heat injection type internal hemorrhoids. Background technique [0002] Hemorrhoids are a common anal disease in clinical practice. It is caused by varicose plexus of the anorectal tail and anal mucosal venous plexus, and then forms one or more venous clusters. Hemorrhoids are a chronic anal disease. Clinically, there are generally three types of hemorrhoids, including internal hemorrhoids, external hemorrhoids and mixed hemorrhoids. The causes of hemorrhoids are more common. Patients have intestinal diseases, bad living habits, toilet habits and external environment. etc. may induce hemorrhoids, which will cause serious harm to the patient's health, and the prevalence of hemorrhoids will increase with age, and the probability of suffering from hemorrhoids will also increase rapidly. In clinical practice, the proportion of women ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/14A61K35/36A61K35/64
Inventor 庄小侃
Owner 庄小侃
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