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Folium callicarpae pedunculalae oral solution for inhibiting gastrointestinal bleeding and preparation method thereof

A Zizhucao oral liquid, gastrointestinal bleeding technology, applied in blood diseases, medical formulas, extracellular fluid diseases, etc., can solve problems such as low cure rate, difficult to obtain medicinal materials, and insignificant therapeutic effect, and achieve The effects of reducing the burden on patients, easy access to drug sources, and low cost of medicinal materials

Inactive Publication Date: 2014-10-29
付丽娜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The prior art, including the above-mentioned patent documents, still has defects such as inaccurate curative effect, insignificant therapeutic effect, and low cure rate in the treatment of gastrointestinal bleeding.
Moreover, some medicinal materials are not easy to obtain, and the cost is relatively high, causing greater economic pressure on patients

Method used

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  • Folium callicarpae pedunculalae oral solution for inhibiting gastrointestinal bleeding and preparation method thereof
  • Folium callicarpae pedunculalae oral solution for inhibiting gastrointestinal bleeding and preparation method thereof
  • Folium callicarpae pedunculalae oral solution for inhibiting gastrointestinal bleeding and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1 Preparation method of Zizhucao oral liquid for inhibiting gastrointestinal bleeding:

[0039] (1) Soak rhubarb and turmeric in a non-iron container for 1 day, put them in a casserole, add water and boil twice, the first time boils for 1 hour, the second time boils for 0.5 hours, and the two filtrates are combined. Concentrate to a thick paste, dry to obtain rhubarb water extract and turmeric water extract respectively;

[0040] (2) Put the Fructus Fructus Fructus and Psoralen Fructus respectively in a casserole, add water, cut them open with strong fire, turn to slow fire and boil for 20 minutes, let stand, filter, concentrate, and dry to obtain the water extract of Fructus Fructus Fructus Fructus Fructus and Psoralen Fructus respectively water extract;

[0041] (3) Make arborina chinensis into coarse powder, extract twice with water, boil for 1-2 hours each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir thoroughly, wash, a...

Embodiment 2

[0046] Example 2 Preparation method of Zizhucao oral liquid for inhibiting gastrointestinal bleeding:

[0047] (1) Soak rhubarb and turmeric in a non-iron container for 2 days, put them in a casserole, add water and boil twice, boil for 2 hours for the first time, and 1 hour for the second time, combine the two filtrates, Concentrate to a thick paste, dry to obtain rhubarb water extract and turmeric water extract respectively;

[0048] (2) Put the Fructus Fructus Fructus and Psoralen Fructus respectively in a casserole, add water, cut them open with strong fire, turn to slow fire and cook for 40 minutes, let stand, filter, concentrate, and dry to obtain the Fructus Fructus Fructus Water Extract and Psoralen Fructus respectively water extract;

[0049] (3) Make arborina chinensis into coarse powder, extract twice with water, boil for 1-2 hours each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir thoroughly, wash, and separate on a distributio...

Embodiment 3

[0054] Example 3 Preparation method of Zizhucao oral liquid for inhibiting gastrointestinal bleeding:

[0055] (1) Soak rhubarb and turmeric in a non-iron container for 1-2 days, put them in a casserole, add water and cook twice, the first time boils for 1.2 hours, the second time boils for 0.6 hours, and the filtrate Combined, concentrated to a thick paste, dried to obtain rhubarb aqueous extract and turmeric aqueous extract;

[0056] (2) Put the Fructus Fructus Fructus and Psoralen Fructus in a casserole, add water, cut them open with strong fire, turn to slow fire and cook for 25 minutes, let stand, filter, concentrate, and dry to obtain the aqueous extract of Fructus Fructus Fructus Fructus Fructus and Psoralen Fructus respectively water extract;

[0057] (3) Make arborina chinensis into coarse powder, extract twice with water, boil for 1 hour each time, combine the two filtrates, concentrate to a thick paste, add ethanol, stir well, wash, separate on a distribution fun...

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Abstract

The invention discloses a folium callicarpae pedunculalae oral solution for inhibiting gastrointestinal bleeding. Each 100ml of the oral solution comprises the following main components: 8g-15g of aqueous fructus aurantii extract, 6g-12g of aqueous folium callicarpae pedunculalae extract, 3g-8g of aqueous rheum officinale extract, 6g-15g of aqueous fructus psoraleae extract and 5g-10g of aqueous radix curcumae extract. In the oral solution disclosed by the invention, the raw traditional Chinese medicines are matched according to syndrome differentiation and assist and complement each other in function so as to effectively play the effects of relieving swelling and pain, replenishing qi to invigorate the spleen, stopping bleeding by generation of muscles, stop bleeding by astringency and stopping bleeding by cooling the blood, so the oral solution has a remarkable curative effect on gastrointestinal bleeding.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a Zizhucao oral liquid for inhibiting gastrointestinal bleeding and a preparation method thereof. Background technique [0002] Gastrointestinal bleeding refers to the bleeding caused by the gastrointestinal tract above the ligament of Trevor, including the esophagus, stomach, duodenum, or pancreaticobiliary. More than 90% of upper gastrointestinal bleeding is caused by peptic ulcer, erosive gastritis, burnt door tear and esophageal and gastric varices. Peptic ulcer bleeding can occur in ulcers in the duodenum, stomach, and surgical anastomotic sites. Patients may have no ulcer pain or dyspepsia, but bleeding is the symptom of peptic ulcer disease. Gastritis Erosive gastritis that leads to bleeding can be caused by drinking alcohol or taking non-group anti-inflammatory drugs (NSAIDS) such as aspirin and ibuprofen. Gastric mucosal erosion is also common in critically...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/08A61P7/04A61P1/00
Inventor 付丽娜
Owner 付丽娜
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