Areca nut cataplasm, preparation method and application thereof

A kind of technology of poultice and betel nut, which is applied in the field of betel nut poultice and its preparation, and achieves the effect of improving medicinal value

Active Publication Date: 2016-02-24
KANGMEI PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main reason is the lack of deep processing and scien

Method used

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  • Areca nut cataplasm, preparation method and application thereof
  • Areca nut cataplasm, preparation method and application thereof
  • Areca nut cataplasm, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0032] Example 1 Preparation of betel nut extract

[0033] The betel nut decoction pieces used in this embodiment are produced in Hainan Province, and the betel nut decoction pieces used for raw use can be purchased from Kangmei Pharmaceutical Co., Ltd.

[0034] Betel nut extract is taken as follows

[0035] Group 1: Areca nut extract

[0036] Take 5,000 grams of betel nut pieces, add 75% ethanol and reflux twice, add 10 times the amount of 75% ethanol based on the weight of the pieces for the first time, reflux for 1 hour, filter and separate the filtrate; add the second time by weight of the pieces 8 times the concentration is 75% ethanol, reflux for 0.5 hour, filter and separate the filtrate. The filtrates were combined, and the filtrate was concentrated under reduced pressure to a density of 1.05 g / mL for use.

[0037] Group 2: Areca Nut Extract

[0038] Take 5,000 grams of betel nut pieces, add 80% ethanol and reflux for two times, add 80% ethanol at 8 times the weight of the pie...

Example Embodiment

[0041] Example 2 Preparation of betel nut cataplasma

[0042] Take an appropriate amount of Carbomer (940) and swell it with water before use to form a 5% gel.

[0043] according to figure 1 with figure 2 The described process prepares betel nut cataplasm.

[0044] The materials used in this embodiment are as follows:

[0045] Group 4: Betel nut cataplasm

[0046] Frame material: 50 parts of sodium polyacrylate (ViscomateNP-700); (American International Specialty Products Company)

[0047] Crosslinking agent: 2 parts of aluminum glycolate; (American International Specialty Products Company)

[0048] 20 parts of propylene glycol; (Tianjin Fuyu Fine Chemical Co., Ltd.)

[0049] Excipients: Carbomer (940) 20 copies; (Beijing Haidianhui Fine Chemical Factory)

[0050] Adhesive: 40 parts of polyvinylpyrrolidone; (Tianjin Damao Chemical Reagent Factory)

[0051] Humectant: 300 parts of glycerin; (Tianjin Damao Chemical Reagent Factory)

[0052] Crosslinking regulator: 1.5 parts of tartaric acid; ...

Example Embodiment

[0073] Example 3 Quality inspection of betel nut cataplasma

[0074] 1) Agilent 1260 Infinity High Performance Liquid Chromatograph, Agilent Technologies, USA

[0075] 2) Chromatographic conditions and system suitability experiment Chromatographic column: DiamonsilC18 (4.6mm×200mm, 5μm); mobile phase: 0.1% triethylamine aqueous solution (pH adjusted to 6.5 with phosphoric acid)-[methanol-acetonitrile (20:30)] (73:27); flow rate 1.0ml / min; detection wavelength 215nm; injection volume 20μl. The number of theoretical plates should not be less than 4000 based on the arecoline peak.

[0076] 2) Preparation of reference substance solution Weigh accurately about 25.0325mg of arecoline hydrobromide reference substance, put it in a 25ml volumetric flask, add 0.001mol / l phosphoric acid solution to dissolve and dilute to the mark, shake well, and get it.

[0077] 3) Preparation of the standard curve. Precisely measure 200μl, 600μl, 1000μl, 2000μl, 6000μl and 8000μl of the above solution, add 0...

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Abstract

The invention provides areca nut cataplasm, a preparation method thereof and application thereof in preparing medicine for expelling parasites, resisting depression and refreshing. The areca nut cataplasm has the advantages that medicinal value of areca nut is increased, damage to the oral cavity caused by arecoline is avoided, concentration of blood and intracerebral medicine is improved, and effects, on expelling parasites, resisting depression and refreshing, of areca nut are enhanced.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine. Specifically, it relates to a betel nut cataplasm and its preparation method and application. Background technique [0002] Betel nut (Arecacatechu L) is a tropical plant widely cultivated in tropical regions, mainly cultivated in Hainan Province in my country. It is one of the main producing areas of betel nut in the world, and its planting area and output have reached a considerable number and scale. Betel nut is a plant of the palm family areca tree, and the utilization of its fruit (also known as betel nut) mainly includes medicinal and edible methods. Betel nut ranks first among the four major southern medicines. It is recorded in traditional Chinese medicine that it has the function of regulating qi and eliminating accumulation, and can treat symptoms such as food accumulation, stagnation of qi, abdominal pain and fullness, and constipation. Its seeds, peels, flowers, etc. can...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K9/70G01N30/02A61P33/02A61P33/10A61P25/24
CPCY02A50/30
Inventor 姜涛乐智勇陈华师许冬瑾马兴田
Owner KANGMEI PHARMA
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