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Uv compositions having low active concentrations and high in vivo spf

A technology of active substances and compositions, applied in the field of stable combination of UV active ingredients, can solve problems such as incompatibility

Inactive Publication Date: 2016-03-02
PROCTER & GAMBLE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Both are reported as SPF (Sun Protection Factor), but unfortunately the value from one pathway does not correspond to the value from the other

Method used

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  • Uv compositions having low active concentrations and high in vivo spf
  • Uv compositions having low active concentrations and high in vivo spf
  • Uv compositions having low active concentrations and high in vivo spf

Examples

Experimental program
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preparation example Construction

[0073] A preferred thickener for use in the present invention is an acrylate crosslinked silicone copolymer network (sometimes referred to as a "polyacrylate siloxane copolymer network") and its preparation is fully disclosed in 2008 In US Patent Publication 2008 / 0051497A1, Lu et al., published February 28, 2008. These copolymers contain the following reaction products:

[0074] a) M a m H b-h-k m PE h m E k D. c D. H d-i-l D. PE i D. E l TeT H f-j-m T PE j T E m Q g and

[0075] b) acrylates in stoichiometric or superstoichiometric amounts, wherein:

[0076] M=R 1 R 2 R 3 SiO 1 / 2 ;

[0077] m H =R 4 R 5 HSio 1 / 2 ;

[0078] m PE =R 4 R 5 (--

[0079] CH 2 CH(R 9 )(R 10 ) n O(R 11 ) o (C 2 h 4 O) p (C 3 h 6 O) q (C 4 h 8 O) r R 12 ) SiO 1 / 2 ;

[0080] m E =R 4 R 5 (--R 17 R 18 C--CR 16 Q s Q t R 15 (COC)R 13 R 14 ) SiO 1 / 2

[0081] D=R 6 R 7 SiO 2 / 2 ;and

[0082] D. H =R 8 HSio 2 / 2

[0083] D. PE =R 8 ...

example

[0157] The following are examples of compositions comprising UV actives.

[0158] sunscreen composition

[0159] The following are examples of sunscreen compositions using a combination of UV actives and stabilizers. Solastay S1 (ethylhexylmethoxycrine) from Hallstar is exemplified as a preferred stabilizer according to the invention. Also exemplified are superabsorbent polymers and silicone elastomers. The in vivo SPF for the examples below ranges from as low as 15 to over 50 SPF. The compositions in Examples 1 to 15 were prepared as follows. In a suitable vessel, combine the water phase ingredients and heat to 75°C. In a separate suitable vessel, the oil phase ingredients were combined and heated to 75°C. The oil phase is then added to the water phase, and the resulting emulsion is milled (eg, using rotor-stator milling). The thickener was then added to the emulsion, and while stirring, the emulsion was cooled to 45°C. At 45°C, the remaining additional ingredients w...

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Abstract

A UV composition that contains from about 0.2% to about 2% of a UV stabilizer which is an alpha-cyanodiphenylacrylate of the general formula: At least one of R1 or R2 is a C1-C8 alkyoxy radical, and one of R1 or R2 is a straight or branched chain C1-C30 alkoxy radical or any non-alkoxy radical, or hydrogen; and R3 is a straight or branched chain C1-C30 alkyl. Further, the UV composition comprises from about 1.5% to about 3.5% of a UV active which is a butyl methoxydibenzoylmethane, and from about 3% to about 9% of a UV active that is 2-Ethylhexyl-3-(4-methoxyphenyl)prop-2-enoate. A dermatologically acceptable carrier is also provided. Preferably, the weight ratio of alpha- cyanodiphenylacrylate to butyl methoxydibenzoylmethane is from about 1:2 to about 1:5.

Description

technical field [0001] The present invention relates to stable combinations of UV active ingredients that provide high in vivo SPF at low levels. Background technique [0002] Skin care compositions comprising different concentrations of UV actives are known. UV actives, while providing beneficial protection against harmful sun rays, do not feel good on the skin. Unfavorable organoleptic aspects of UV actives are also known. Thus, increasing UV actives may provide enhanced sun protection, but it results in a less pleasant product feel. [0003] Furthermore, added UV active substances are generally inactivated during storage or shortly after application to the skin. To provide the desired level of sun protection over time, excess UV actives are often added to skin care compositions, which exacerbates adverse sensory issues. Stabilizing UV actives against degradation over time is a key quality in formulating desirable UV skin care compositions that provide the necessary pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/35A61K8/37A61K8/40A61Q17/04
CPCA61K8/35A61K8/37A61K8/40A61K2800/52A61Q17/04A61K45/06
Inventor R·A·芬利R·J·佩列斯P·R·坦纳
Owner PROCTER & GAMBLE CO
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