Topical ointment for treating kinesia and producing method thereof
A motion sickness and ointment technology, which is applied in the field of medicines for the treatment of motion sickness, can solve the problems of application limitation, difficulty in guaranteeing the efficacy of medicine, and limitation on the area of the plaster.
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Embodiment 1
[0030] (1) Precisely weigh 2.72g of scopolamine hydrobromide and dissolve it in 22.48g of azone to make phase A;
[0031] (2) Weigh 36.6g of camphor and 36.6g of menthol, grind and dissolve in 36.6g of eucalyptus oil to make phase B;
[0032] (3) Add 110g of lanolin and 755g of white petrolatum in turn to phase A, stir well while adding, and gradually heat and stir at a temperature lower than 60°C to melt the lanolin and white petrolatum, then add phase B to make 1000g, Stir well and serve.
Embodiment 2
[0034] (1) Precisely weigh 3.68g of scopolamine hydrobromide and dissolve it in 20.32g of azone to make phase A;
[0035] (2) Weigh 27.0g of camphor and 27.0g of menthol, grind and dissolve in 27.0g of eucalyptus oil to make phase B;
[0036] (3) Add 105g of lanolin and 790g of white petrolatum in sequence to phase A, stir evenly while adding, and gradually heat and stir at a temperature lower than 60°C to melt the lanolin and white petrolatum, then add phase B to make 1000g, Stir well and serve.
Embodiment 3
[0038] (1) Precisely weigh 3.0 g of scopolamine hydrobromide and dissolve it in 21.0 g of azone to make phase A;
[0039] (2) Weigh 32.0g of camphor and 32.0g of menthol, grind and dissolve in 32.0g of eucalyptus oil to make phase B;
[0040] (3) Add 100g of lanolin and 780g of white petrolatum in turn to phase A, stir evenly while adding, and gradually heat and stir at a temperature lower than 60°C to melt the lanolin and white petrolatum, then add phase B to make 1000g, Stir well and serve.
[0041] The shape of the external ointment for treating motion sickness made by embodiment 1-3 is light yellow ointment, gas fragrance, has cool and refreshing stimulation.
[0042] Using thin-layer chromatography, ether, absolute ethanol, and petroleum ether were used as solvents, ether-dilute ethanol (1:1), cyclohexane-ethyl acetate (19:1), toluene-ethyl acetate (19:1) :1) as a developing agent to identify scopolamine hydrobromide, eucalyptus oil and menthol in the ointment; in the c...
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