Heparin sodium lotion and method for preparing same

The technology of heparin sodium lotion and heparin sodium is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, inorganic active ingredients, etc., and achieves the effects of convenient use, reasonable prescription compatibility and simple preparation method.

Inactive Publication Date: 2016-04-27
KAMP PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many disadvantages in the effectiveness, safety, aspect and other aspects of the commercially available medicines for treating burns and scalds

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] prescription:

[0021] Each 100 ml contains 0-25000 units of heparin sodium, 50 grams of silver sulfadiazine, 20 grams of sodium hyaluronate, 10 grams of zinc oxide, 15 ml of glycerin, 5 grams of menthol, and the balance is purified water.

[0022] Preparation:

[0023] Grind sodium heparin, silver sulfadiazine, zinc oxide, sodium hyaluronate, menthol, and glycerin into a paste, add a small amount of purified water to continue grinding, and finally add the remaining amount of purified water, stir well, and divide into packages to obtain the product.

Embodiment 2

[0025] prescription:

[0026] Each 100 ml contains 0-25000 units of heparin sodium, 40 grams of silver sulfadiazine, 20 grams of sodium hyaluronate, 10 grams of zinc oxide, 30 ml of glycerin, 10 grams of menthol, and the balance is purified water.

[0027] Preparation:

[0028] Grind sodium heparin, silver sulfadiazine, zinc oxide, sodium hyaluronate, menthol, and glycerin into a paste, add a small amount of purified water to continue grinding, and finally add the remaining amount of purified water, stir well, and divide into packages to obtain the product.

[0029] Clinical Efficacy Data:

[0030] 1. Sample information:

[0031] In clinical trials, 100 burn patients met the diagnostic criteria for Ⅰ-Ⅱ degree burns. Among the 100 patients, there were 55 males and 45 females; age: 15-64 years old, average 32 years old; burn site: 15 cases of head and face, 28 cases of chest and abdomen, 57 cases of extremities; burn area: 2%-15% , with an average of 12%; degree of burns: ...

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PUM

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Abstract

The invention discloses heparin sodium lotion and a method for preparing the same. The heparin sodium lotion comprises principle compositions and pharmaceutical excipients. The principle compositions include heparin and silver sulfadiazine, and the pharmaceutical excipients include sodium hyaluronate, zinc oxide, glycerin, menthol and purified water. The heparin sodium lotion and the method have the advantages that the method for preparing the heparin sodium lotion is simple, the heparin sodium lotion is convenient to use, and excellent curative effects of resisting inflammation, inhibiting germs and relieving pain can be realized by the heparin sodium lotion.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a heparin sodium medicinal lotion for treating burn wounds and a preparation method thereof. Background technique [0002] Heparin sodium is a commonly used clinical drug for anticoagulation and prevention of thrombosis. It is commonly used clinically to prevent and treat thrombosis or embolism diseases (such as myocardial infarction, thrombophlebitis, pulmonary embolism, etc.); disseminated intravascular coagulation (DIC) caused by various reasons; also used in hemodialysis, extracorporeal circulation, catheterization , microvascular surgery and other operations and anticoagulant treatment of certain blood samples or instruments. Heparin sodium has a strong anticoagulant effect, and is the drug of choice for preventing deep venous thrombosis and other thromboembolic diseases. , anti-allergic, anti-viral, anti-cancer and other biological functions. [0003] Burns are...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61P17/02A61K31/728A61K31/727A61K31/635A61K31/045
Inventor 曾培安曾灿丽吴健民贺莲张静刘娟
Owner KAMP PHARMA
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