Drug for treating urinary calculi and preparation method thereof

A technology for urinary stones and medicines, which is applied in the direction of urinary system diseases, medical formulas, drug combinations, etc., can solve the problems of unsatisfactory treatment effect, low cure rate, toxic and side effects, and achieve safety, non-toxic and side effects, quick results, The effect of reducing the degree of gallstones

Inactive Publication Date: 2016-06-22
QINGDAO YUANZHILIN AGRI SCI & TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In terms of drug treatment, there are various traditional Chinese medicines and western medicines used to treat calculi on the market, and there are generally disadvantages such as slow drug properties, long course of treatment, and low cure rate when taking them; and some patients need to take them for a long time. Toxic and side effects, unsatisfactory treatment effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Dispensing according to the raw materials and composition weight of the following active ingredients of the drug:

[0046] Radix: 20 parts; Mallow: 18 parts; Akebia: 10 parts; Curcuma: 14 parts; Turtle Shell: 20 parts;

[0047] Notoginseng powder: 15 parts; Myrrha: 10 parts; Raw Shouwu: 14 parts; Shepherd's purse flower: 22 parts; Alisma: 10 parts;

[0048] Gentian: 15 parts; Borax: 8 parts; Raw calamus: 12 parts; Licorice shoots: 15 parts;

[0049] Citrus aurantium: 10 parts; Qingpi: 6 parts; Honeysuckle: 9 parts; Eclipta: 11 parts.

Embodiment 2

[0051] Take the medicinal materials according to the weight ratio of Example 1, decoct for the first time and add 8-10 times of the total weight of the medicinal materials to decoct and extract, decoct for 1.5-2.5 hours, filter the medicinal liquid for use: the second time Add 6-8 times the amount of water, decoct for 1-1.2 hours, filter out the medicinal solution for later use; add 6-8 times the amount of water for the third time, decoct for 0.8-1.2 hours, and filter the medicinal solution for later use; combine Decoct the solution three times, filter and collect the filtrate; concentrate the filtrate to a relative density of 1-1.1 at 60°C; centrifuge at a speed of 3000r / min; spray dry at 60°C-80°C to obtain a dry extract;

[0052] Pulverize the prepared dry extract, add appropriate amount of sucrose and dextrin to mix, use ethanol as wetting agent, granulate, dry, and granulate to obtain granules;

Embodiment 3

[0054] Take the medicinal materials according to the weight ratio of Example 1, decoct for the first time and add 8-10 times of the total weight of the medicinal materials to decoct and extract, decoct for 1.5-2.5 hours, filter the medicinal liquid for use: the second time Add 6-8 times the amount of water, decoct for 1-1.2 hours, filter out the medicinal solution for later use; add 6-8 times the amount of water for the third time, decoct for 0.8-1.2 hours, and filter the medicinal solution for later use; combine Decoct the solution three times, filter and collect the filtrate; concentrate the filtrate to a relative density of 1-1.1 at 60°C; centrifuge at a speed of 3000r / min; spray dry at 60°C-80°C to obtain a dry extract;

[0055] Dry the obtained dry extract, pulverize it, and make a powder;

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PUM

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Abstract

The invention provides a drug for treating urinary calculi. The drug is prepared from, by weight, 20 parts of radish seeds, 18 parts of chingma abutilon seeds, 10 parts of akebia stems, 14 parts of curcuma zedoary, 20 parts of carapax trionycis, 15 parts of spina gleditsiae, 15 parts of radix notoginseng powder, 10 parts of processed myrrh, 14 parts of fresh radix polygoni multiflori, 22 parts of shepherd's purse flowers, 10 parts of rhizoma alismatis, 15 parts of gentian, 8 parts of borax, 12 parts of fresh rhizoma acori tatarinowii, 15 parts of ural licorice root tips, 10 parts of fructus aurantii, 6 parts of green tangerine peel, 9 parts of honeysuckle flowers and 11 parts of herbal ecliptae. According to the traditional Chinese medicine composition, the selected medicinal materials are under proper compatibility, and the drug conforms to the traditional Chinese medicine and modern medicine and pharmacology theories and has a remarkable effect on reducing the degree of calculi and obvious analgesia and diuresis effects. It is clinically verified that the traditional Chinese medicine composition achieves a good curative effect and is small in toxic and side effect, the effect is taken quickly, urinary calculi will not relapse after being cured, and clinical popularization value is achieved.

Description

technical field [0001] The invention belongs to the field of medical drugs, and in particular relates to a drug for treating urinary calculi and a preparation method thereof. Background technique [0002] Urinary calculus is a common disease of the urinary system. Stones can occur anywhere in the kidneys, bladder, ureters, and urethra. But kidney and ureteral stones are common. Clinical manifestations vary depending on the location of the stone. Urinary calculus is a common disease worldwide, and the incidence rate in our country is also relatively high. [0003] The typical manifestations of kidney and ureteral stones are renal colic and hematuria. Before the onset of colic caused by stones, the patient does not feel anything. Due to certain inducements, such as strenuous exercise, labor, long-distance driving, etc., sudden severe pain in one side of the waist. Colic, and radiation to the lower abdomen and perineum, accompanied by abdominal distension, nausea, vomiting,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P13/04A61P13/12A61K33/22A61K35/586
CPCA61K36/31A61K9/08A61K9/14A61K9/1623A61K9/1652A61K9/2059A61K33/22A61K35/586A61K36/185A61K36/258A61K36/28A61K36/328A61K36/355A61K36/483A61K36/484A61K36/515A61K36/704A61K36/752A61K36/884A61K36/888A61K36/9066A61K47/26A61K2300/00
Inventor 刘书元
Owner QINGDAO YUANZHILIN AGRI SCI & TECH DEV
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