Traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury and preparation method thereof

A technology of renal ischemia-reperfusion and composition, applied in the field of traditional Chinese medicine preparations, can solve the problems of aggravating kidney damage, aggravating cell metabolism disorder, etc., and achieves the effects of good retention, short drying time and low energy consumption

Active Publication Date: 2019-07-12
黄国东
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Restoration of renal blood flow after ischemia exacerbates cellular metabolic disturbances, leading to aggravated renal injury

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury and preparation method thereof
  • Traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury and preparation method thereof
  • Traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury, which is mainly made of the following raw materials in parts by weight: 50 parts of hydatid grass, 8 parts of Panax notoginseng, 12 parts of coix seed, 8 parts of rhubarb, 12 parts of astragalus and Licorice 4 parts.

[0031] A preparation method of a traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury, comprising the steps of:

[0032] Step 1: Collect fresh hydrangea from July to September every year, spread it on a tray with holes, and dry it with superheated steam until its water content is less than 12%, to obtain hydrangea;

[0033] Step 2. Weigh the above-mentioned parts by weight of Hydrangea chinensis, and crush it to 30 mesh to obtain Hydrangea powder; weigh the above-mentioned parts by weight of rhubarb, astragalus and licorice, mix and crush to 60 mesh, to obtain the first mixed powder ; Weighing the abo...

Embodiment 2

[0044] A traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury, which is mainly made of the following raw materials in parts by weight: 60 parts of hydatid grass, 10 parts of Panax notoginseng, 15 parts of coix seed, 10 parts of rhubarb, 15 parts of astragalus and 6 parts of licorice.

[0045] A preparation method of a traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury, comprising the steps of:

[0046] Step 1: Collect fresh hydrangea from July to September every year, spread it on a tray with holes, and dry it with superheated steam until its water content is less than 12%, to obtain hydrangea;

[0047] Step 2. Weigh the above weight portion of Hydrangea chinensis, and crush it to 40 mesh to obtain Hydrangea powder; weigh the above weight portion of rhubarb, astragalus and licorice, mix and crush to 70 mesh, to obtain the first mixed powder ; Weigh the Panax notoginseng and c...

Embodiment 3

[0058] A traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury, which is mainly made of the following raw materials in parts by weight: 70 parts of hydatid grass, 12 parts of Panax notoginseng, 18 parts of coix seed, 12 parts of rhubarb, 18 parts of astragalus and 8 parts of licorice.

[0059] A preparation method of a traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury, comprising the steps of:

[0060] Step 1: Collect fresh hydrangea from July to September every year, spread it on a tray with holes, and dry it with superheated steam until its water content is less than 12%, to obtain hydrangea;

[0061] Step 2: Take the above-mentioned parts by weight of Hydrangea chinensis, and pulverize it to 50 mesh to obtain Hydrangea powder; weigh the above-mentioned parts by weight of rhubarb, astragalus and licorice, mix and pulverize to 80 mesh, to obtain the first mixed powder ; Weig...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a Chinese medicinal composition for preventing and treating renal ischemia reperfusion injury. The Chinese medicinal composition is mainly prepared from the following raw materials in parts by weight: 50-70 parts of galium aparine, 8-12 parts of radix notoginseng, 12-18 parts of semen coicis, 8-12 parts of prepared rheum officinale, 12-18 parts of radix astragali and 4-8 parts of radix glycyrrhizae. A preparation method of the Chinese medicinal composition for preventing and treating renal ischemia reperfusion injury mainly comprises the following steps: drying the galium aparine; mixing the prepared rheum officinale, the radix astragali and the radix glycyrrhizae, smashing the mixture, and performing trapezoidal reflux extraction on the smashed mixture with ethanol; smashing the galium aparine, and performing ultrasonic wave-assisted water extraction and ethanol reflux extraction on the smashed galium aparine; performing superfine grinding on the radix notoginseng and the semen coicis, and performing ultrasonic wave-assisted alcohol extraction; combining and concentrating extraction solutions. The Chinese medicinal composition has the effects of clearing heat, promoting diuresis, promoting blood circulation to remove blood stasis, eliminating evil without injuring healthy energy and strengthening healthy energy without retaining evil, and has remarkable prevention and treatment effects on renal ischemia reperfusion injury.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations. More specifically, the present invention relates to a traditional Chinese medicine composition for preventing and treating renal ischemia-reperfusion injury and a preparation method thereof. Background technique [0002] Ischemia reperfusion injury (Ischemia reperfusion injury, IRI) is more commonly seen clinically in operations such as blood loss or toxic shock, intravascular coagulation, kidney transplantation, partial nephrectomy, and nephrolithotomy. Restoration of renal blood flow after ischemia exacerbates cellular metabolic disturbances, resulting in aggravated renal injury. Ischemia-reperfusion injury is an important part of ischemic acute kidney injury, a key link in the prevention and treatment of acute renal failure, and the main factor affecting the early functional recovery and long-term survival of the kidney in kidney transplantation; prevention and treatme...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P13/12
CPCA61K9/0095A61K36/258A61K36/481A61K36/484A61K36/53A61K36/708A61K36/8994A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 黄国东陈壮向少伟马晓露黄敏
Owner 黄国东
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap