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Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia

A technology for trigeminal neuralgia and inflammation of the liver, which is applied in the field of traditional Chinese medicine, can solve problems such as low effective rate, many complications, and difficult to cure, and achieve the effect of low treatment cost, no toxic side effects, and pain relief

Inactive Publication Date: 2016-07-27
陈红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine is quick to take effect, but the effective rate is low (60%-80%), and the recurrence rate is high
Closed treatment is also difficult to cure, and there are more complications

Method used

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  • Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia
  • Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia
  • Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Drugs for oral administration - preparation of capsules

[0044] Prescription: 20 parts of Erythrina chinensis, 12 parts of Ganfengcao, 6 parts of Siberian Grass, 10 parts of Gastrodia elata, 9 parts of Citron, 6 parts of Dipsacus, 15 parts of Akebia chinensis, 20 parts of Sunflower Flower Disc, 15 parts of Spirulina 6 parts, licorice.

[0045] Preparation method: Grind bitter grass, ganfengcao, Xixiancao, Gastrodia elata, citron, Dipsacus, akebia, sunflower flower disc, wheat bottle grass, and licorice into coarse powder, add water to soak for 3-4 hours, and fry Boil and extract twice, each time for 1.0-2.0 hours (start timing from boiling), combine the filtrate, add ethanol to make the alcohol content of the solution be 40%, after standing for 12 hours, discard the lower layer of sediment to obtain the supernatant, Concentrate under reduced pressure and dry, and make capsules according to the conventional technology of pharmacy, with a loading capacity of 0.3g per ca...

Embodiment 2

[0050] Drugs for oral administration - preparation of capsules

[0051] Prescription: 22 parts of Erythrina chinensis, 12 parts of Ganfengcao, 8 parts of Siberian Grass, 12 parts of Gastrodia elata, 12 parts of Citron, 6 parts of Dipsacus, 10 parts of Akebia, 18 parts of Sunflower Flower Disc, 13 parts of Spirulina 6 parts, licorice.

[0052] Preparation method: refer to the preparation operation of the capsule in Example 1.

[0053] Drugs for external use - preparation of ointments

[0054] Prescription: 5 parts of Asarum, 18 parts of Sanleng Gucao, 10 parts of Mint, 10 parts of Xu Changqing, and 8 parts of Vitex Vitex.

[0055] Preparation method: refer to the preparation operation of the ointment in Example 1.

Embodiment 3

[0057] Drugs for oral administration - preparation of capsules

[0058] Prescription: 22 parts of Erythrina chinensis, 12 parts of Ganfengcao, 7 parts of Siberian Grass, 8 parts of Gastrodia elata, 10 parts of citron, 8 parts of Dipsacus, 10 parts of Akebia, 20 parts of sunflower flower disc, 14 parts of syringa 7 parts, licorice.

[0059] Preparation method: refer to the preparation operation of the capsule in Example 1.

[0060] Drugs for external use - preparation of ointments

[0061] Prescription: 8 parts of Asarum, 20 parts of Sanleng Gucao, 10 parts of Mint, 12 parts of Xu Changqing, and 7 parts of Vitex Vitex.

[0062] Preparation method: refer to the preparation operation of the ointment in Example 1.

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Abstract

The invention discloses a pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia and a preparation method thereof. The pharmaceutical composition consists of an internal medicine and an external medicine, wherein the internal medicine is prepared from the medicinal raw materials of herb of twospot swertia, autumn zephyrlily herb, glandularstalk St. Paulswort herb, tall gastrodia tuber, citron fruit, Himalayan teasel root, all-grass of loureiro clematis, sunflower receptacle, all-grass of conical silene, and licorice root; and the external medicine is prepared from the medicinal raw materials of manchurian wildginger herb, all grass of highstalk razorsedge, peppermint, paniculate swallowwort root, and twig of negundo chastetree. By virtue of internal and external combined treatment, one one hand, the pharmaceutical composition is capable of smoothing liver to purge heat, calming liver to stop wind, activating meridians to stop pain, and regulating internal organs to achieve an effect of relieving pain, and on the other hand, by directly acting on acupoint meridians to diffuse the efficacy of medicines, the pharmaceutical composition can achieve the effects of relieving and alleviating pain for local qi and blood meridian obstruction caused by exogenous evils, can achieve a satisfactory clinical treatment effect more easily on the whole, and is less in treatment cost and does not have toxic or side effects in comparison with a conventional therapy.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating primary trigeminal neuralgia of liver-fire ascending inflammation type and a preparation method thereof. Background technique [0002] Trigeminal neuralgia is recurrent paroxysmal severe pain in the distribution area of ​​the trigeminal nerve. It is divided into two types: primary and secondary. affim. According to literature reports, 62% of the cases are due to the involvement of the first-order neurons of the trigeminal nerve, which can be seen in infectious diseases such as colds, tonsillitis, and maxillary sinusitis, or blood circulation disorders caused by arteriosclerosis and hypertension; 10% Most of the cases are due to the second-order neurons in the brainstem, that is, the trigeminal nucleus lesion, which is mostly caused by local blood circulation disorders in the brainstem; 12% of the cases are due to dysfu...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61K36/89A61P29/00A61P25/02
CPCA61K36/51A61K9/0014A61K9/0053A61K36/185A61K36/268A61K36/27A61K36/28A61K36/36A61K36/484A61K36/534A61K36/716A61K36/752A61K36/85A61K36/88A61K36/89A61K36/8988A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 陈红
Owner 陈红
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