Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia

A technology for trigeminal neuralgia and inflammation of the liver, which is applied in the field of traditional Chinese medicine, can solve problems such as low effective rate, many complications, and difficult to cure, and achieve the effect of low treatment cost, no toxic side effects, and pain relief

Inactive Publication Date: 2016-07-27
陈红
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AI-Extracted Technical Summary

Problems solved by technology

Western medicine is quick to take effect, but the effective rate is low (60%-80%), and the recu...
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Abstract

The invention discloses a pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia and a preparation method thereof. The pharmaceutical composition consists of an internal medicine and an external medicine, wherein the internal medicine is prepared from the medicinal raw materials of herb of twospot swertia, autumn zephyrlily herb, glandularstalk St. Paulswort herb, tall gastrodia tuber, citron fruit, Himalayan teasel root, all-grass of loureiro clematis, sunflower receptacle, all-grass of conical silene, and licorice root; and the external medicine is prepared from the medicinal raw materials of manchurian wildginger herb, all grass of highstalk razorsedge, peppermint, paniculate swallowwort root, and twig of negundo chastetree. By virtue of internal and external combined treatment, one one hand, the pharmaceutical composition is capable of smoothing liver to purge heat, calming liver to stop wind, activating meridians to stop pain, and regulating internal organs to achieve an effect of relieving pain, and on the other hand, by directly acting on acupoint meridians to diffuse the efficacy of medicines, the pharmaceutical composition can achieve the effects of relieving and alleviating pain for local qi and blood meridian obstruction caused by exogenous evils, can achieve a satisfactory clinical treatment effect more easily on the whole, and is less in treatment cost and does not have toxic or side effects in comparison with a conventional therapy.

Application Domain

Technology Topic

PeppermintsSwertia +13

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  • Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia
  • Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia
  • Pharmaceutical composition for treating liver fire flaming type primary trigeminal neuralgia

Examples

  • Experimental program(10)

Example Embodiment

[0042] Example 1
[0043] Oral medicine-preparation of capsules
[0044] Prescription: 20 parts of Great Sophora, 12 parts of Hepatica spp., 6 parts of Asparagus grass, 10 parts of Gastrodia, 9 parts of Citron, 6 parts of Dipsacus, 15 parts of Jinsi Mutong, 20 parts of Sunflower Flower Plate, 15 parts of Elysium Servings, 6 servings of licorice.
[0045] Preparation method: Take big bitter grass, liver wind grass, oxen grass, gastrodia, citron, Dipsacus, Jinsi Mutong, sunflower flower tray, siphon grass, licorice and crush into coarse powder, soak in water for 3-4 hours, and fry Boil and extract twice, 1.0-2.0 hours each time (from the time of boiling), combine the filtrate, add ethanol to make the solution alcohol content 40%, after standing for 12 hours, discard the lower sediment to obtain the supernatant, After concentrating under reduced pressure, it is dried and made into capsules according to the conventional techniques of pharmacy. Each capsule contains 0.3g, equivalent to 0.6g of crude drug.
[0046] External medicine-preparation of ointment
[0047] Prescription: 6 parts of Asarum, 16 parts of San Leng Ajugae Herb, 9 parts of Mint, 12 parts of Xu Changqing, 10 parts of Huang Jingzhi.
[0048] Preparation method: Take Asarum, Sanleng Ajuga, Xu Changqing, Huang Jingzhi, and mint into particles with an average particle size of 30-80 μm, then add 3-7 times the amount of 60% ethanol aqueous solution, and use ultrasonic extraction. The extraction conditions include: The ultrasonic power is 150-160W, the extraction temperature is 35-40℃, and the extraction time is 20-40min; after ultrasonic extraction, take the filtrate and concentrate under reduced pressure to obtain the extract; melt the petroleum jelly and boil, and add the extract at a constant speed under stirring In white petrolatum, encapsulate after sterilization to obtain ointment.

Example Embodiment

[0049] Example 2
[0050] Oral medicine-preparation of capsules
[0051] Prescriptions: 22 parts of Sophora vulgaris, 12 parts of Hepatica spp., 8 parts of Asparagus grass, 12 parts of Gastrodia, 12 parts of Citron, 6 parts of Dipsacus, 10 parts of Jinsimutong, 18 parts of Sunflower Flower Plate, 13 Servings, 6 servings of licorice.
[0052] Preparation method: Refer to the preparation operation of the capsule in Example 1.
[0053] External medicine-preparation of ointment
[0054] Prescription: 5 parts of Asarum, 18 parts of Sanleng Ajuga, 10 parts of Mint, 10 parts of Xu Changqing, 8 parts of Huang Jingzhi.
[0055] Preparation method: Refer to the preparation operation of Example 1 ointment.

Example Embodiment

[0056] Example 3
[0057] Oral medicine-preparation of capsules
[0058] Prescription: 22 parts of Sophora vulgaris, 12 parts of Hepatica spp., 7 parts of Asparagus grass, 8 parts of Gastrodia, 10 parts of Citron, 8 parts of Dipsacus, 10 parts of Jinsi Mutong, 20 parts of Sunflower Flower Plate, 14 7 servings of licorice.
[0059] Preparation method: Refer to the preparation operation of the capsule in Example 1.
[0060] External medicine-preparation of ointment
[0061] Prescription: 8 parts of Asarum, 20 parts of San Leng Ajuga, 10 parts of Mint, 12 parts of Xu Changqing, 7 parts of Huang Jingzhi.
[0062] Preparation method: Refer to the preparation operation of Example 1 ointment.
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Description & Claims & Application Information

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