A kind of traditional Chinese medicine composition, its fermented medicinal liquid prepared by it, preparation method and application

Abstract

The invention discloses a traditional Chinese medicine composition, fermented medicine liquor prepared from the traditional Chinese medicine composition, a preparation method and application. The traditional Chinese medicine composition is prepared from, by weight, 160-480 parts of kudzuvine roots, 80-320 parts of radix salvia miltiorrhiza, 120-400 parts of radix paeoniae alba, 120-400 parts of milkvetch roots, 40-240 parts of rhizoma curcumae longae, 60-280 parts of rhizoma atractylodis macrocephalae, 40-240 parts of semen brassicae, 60-280 parts of fructus crataegi, 60-280 parts of radix bupleuri, 60-280 parts of flos chrysanthemi, 40-240 parts of rhizoma gastrodiae, 60-280 parts of rhizome panacis japonica, 60-280 parts of rhizoma cyperi and 40-240 parts of herba salviae chinensis. Every 1,000 parts by weight of the fermented medicine liquor is prepared by adding and fermenting, by weight, 10-50 parts of saccharomyces cerevisiae, 10-50 parts of bacillus aceticus, 10-50 parts of lactobacillus and the balance traditional Chinese medicine decoction. Experiments show that the fermented medicine liquor has the obvious effect on oxidative stress injuries of cerebral microvascular endothelial cells and can significantly inhibit cerebral microvascular endothelial cell apoptosis and aging which are induced by hydrogen peroxide. Clinical experiments show that the fermented medicine liquor prepared from the traditional Chinese medicine composition can effectively treat ischemic encephalopathy, is safe and effective in treatment, has no adverse influence on the liver and kidney functions of a patient, can be taken for a long term and is worthy of clinical application and popularization.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, a fermented liquid prepared therefrom, and a preparation method and application thereof, and is particularly suitable for the treatment of ischemic encephalopathy. Background technique [0002] Ischemic encephalopathy (ischemic encephalopathy): Refers to brain damage caused by hypotension, cardiac arrest, blood loss, asphyxia and other reasons. The clinical encephalopathy caused by cerebral ischemia includes ischemic stroke, vascular dementia, headache, dizziness, depression, tinnitus and insomnia, etc., and has the characteristics of high morbidity, disability, and mortality. It is one of the three major diseases leading to human death, second only to heart disease and cancer. [0003] The main causes of ischemic encephalopathy are: ① stenosis or occlusion of intracranial and external arteries; ② cerebral artery embolism...

AI Technical Summary

Problems solved by technology

Although some therapeutic drugs have been developed on the market, due to the diversity and complexity of ischemic encephalopathy, although these drugs have shown certain curative effects in the treatment, they all work through a single mechanism, and there are always some shortcomings.

Images