Oxidation-resistant astaxanthin mask and preparation method thereof

An astaxanthin and antioxidant technology, applied in cosmetic preparations, cosmetics, pharmaceutical formulations, etc., can solve problems such as rough skin, dullness and dullness, slow down skin aging, promote cell metabolism, and repair damaged epidermis cells. Effect

Inactive Publication Date: 2016-08-24
李建东
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The main purpose of the present invention is to provide an astaxanthin anti-oxid

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  • Oxidation-resistant astaxanthin mask and preparation method thereof

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preparation example Construction

[0018] The embodiment of the present invention provides an astaxanthin anti-oxidation facial mask, the ingredients of which are calculated in parts by weight: 5-15 parts of glycerin, 5-10 parts of honey, 5-15 parts of aloe extract, 2-10 parts of lemon oil 5-10 parts of arbutin, 2-5 parts of astaxanthin, 4-10 parts of hydroxypropyl-β-cyclodextrin, 2-5 parts of ethanol, 0.01-0.1 parts of methylparaben, 30 parts of distilled water ~45 parts The present invention also provides a kind of preparation method of astaxanthin anti-oxidation mask, comprising the following steps:

[0019] Step S101, dissolving astaxanthin and hydroxypropyl-β-cyclodextrin in dichloromethane and methanol respectively, and then fully mixing the above-mentioned substances under a nitrogen atmosphere.

[0020] Step S102, the above mixture is ultrasonically treated and vacuum-dried to prepare an astaxanthin / hydroxypropyl-β-cyclodextrin inclusion compound, and then redispersed in distilled water, filtered, and f...

Embodiment 1

[0025] Step 1: Accurately weigh 3mg of astaxanthin and dissolve in 3mL of dichloromethane; accurately weigh 6mg of hydroxypropyl-β-cyclodextrin and dissolve in 12mL of methanol. The materials were mixed well under nitrogen atmosphere.

[0026] Step 2: The mixture obtained in step 1 was sonicated at 500W, the sonication interval was 2s, the sonication time was 3s, and the total sonication time was 5min, to obtain astaxanthin / hydroxypropyl-β-cyclodextrin inclusion compound. Then placed in a vacuum oven at 25°C for 24h. The dried clathrate powder was redispersed in 5 mL of distilled water, stirred evenly to dissolve, and then filtered to remove impurities. Finally, the filtered solution was placed in a freeze dryer for 48 hours to obtain a pure astaxanthin / hydroxypropyl-β-cyclodextrin inclusion compound.

[0027] Step 3: Accurately weigh 35mg of distilled water into a beaker, then add 15mg of glycerin, 9mg of honey, 14mg of aloe extract, 8mg of lemon oil, 5mg of arbutin, 3mg of...

Embodiment 2

[0031] Step 1: Accurately weigh 4 mg of astaxanthin, dissolve in 4 mL of dichloromethane; accurately weigh 8 mg of hydroxypropyl-β-cyclodextrin, and dissolve in 16 mL of methanol. The materials were mixed well under nitrogen atmosphere.

[0032] Step 2: The mixture obtained in step 1 was sonicated at 500W, the sonication interval was 2s, the sonication time was 3s, and the total sonication time was 5min, to obtain astaxanthin / hydroxypropyl-β-cyclodextrin inclusion compound. Then place it in a vacuum oven at 25°C for 24 hours, redisperse the dried clathrate powder in 5 mL of distilled water, stir evenly to dissolve, and then filter to remove impurities. Finally, the filtered solution was placed in a freeze dryer for 48 hours to obtain a pure astaxanthin / hydroxypropyl-β-cyclodextrin inclusion compound.

[0033] Step 3: Accurately weigh 40mg of distilled water into a beaker, then add 10mg of glycerin, 8mg of honey, 10mg of aloe extract, 5mg of lemon oil, 5mg of arbutin, 5mg of e...

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Abstract

The invention discloses an astaxanthin mask having an oxidation-resistant effect. The astaxanthin mask is characterized by being prepared from, by weight, 5-15 parts of glycerol, 5-10 parts of honey, 5-15 parts of aloe vera extracting liquid, 2-10 parts of lemon oil, 5-10 parts of arbutin, 2-5 parts of astaxanthin, 4-10 parts of hydroxypropyl-beta-cyclodextrin, 2-5 parts of ethyl alcohol, 0.01-0.1 part of methylparaben and 30-45 parts of distilled water. The astaxanthin is entrapped in the hydroxypropyl-beta-cyclodextrin, so that the solubility of the astaxanthin in mask essence is improved. The astaxanthin mask has the very good oxidation-resistant effect, can effectively remove facial oxygen free radicals and promote cell metabolism, and makes the skin rejuvenated. In addition, the astaxanthin mask also has the effects of whitening, moisturizing, minimizing pores and the like, and keeps the skin exquisite, moisturized and smooth.

Description

technical field [0001] The invention belongs to the technical field of daily skin care products, and in particular relates to an astaxanthin anti-oxidation mask and a preparation method thereof. Background technique [0002] Astaxanthin is a terpene-like unsaturated compound belonging to the xanthophyll-β-carotene family. It widely exists in the biological world, especially in the feathers of shrimp, crab, fish, algae, yeast and birds. Astaxanthin is a natural antioxidant, which can effectively remove oxygen free radicals in cells and prevent oxidative damage to tissues, cells, and DNA. It is called "super vitamin E". Its antioxidant capacity is 1000 times that of vitamin E, and it is coenzyme Q 10 800 times. At the same time, astaxanthin also has physiological activities such as anti-radiation, anti-tumor and prevention of cardiovascular and cerebrovascular diseases. Therefore, astaxanthin has important application value in the field of cosmetics. [0003] With the gro...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61K8/35A61K8/60A61K8/73A61K8/92A61K8/97A61K8/34A61Q19/08
CPCA61K8/345A61K8/35A61K8/602A61K8/738A61K8/922A61K8/97A61K8/988A61Q19/08
Inventor 李建东贝维亚王苗苗陈亮
Owner 李建东
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