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Maternal-fetal blood group incompatibility adsorption therapy device

A blood type incompatibility, therapeutic device technology, applied in suction devices, other medical devices, blood circulation treatment, etc., to achieve the effect of enhancing effect, increasing uniformity and surface area

Active Publication Date: 2019-01-22
ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But so far there is no report on the design of the treatment of blood group incompatibility hemolytic disease according to the above mechanism

Method used

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  • Maternal-fetal blood group incompatibility adsorption therapy device
  • Maternal-fetal blood group incompatibility adsorption therapy device
  • Maternal-fetal blood group incompatibility adsorption therapy device

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Embodiment Construction

[0012] figure 1 It is a schematic diagram of the application of the adsorption therapeutic apparatus for maternal-fetal blood group incompatibility proposed according to the present invention.

[0013] figure 2 It is the internal structure diagram of the plasma separator proposed according to the present invention.

[0014] image 3 is the internal structure diagram of the adsorber proposed according to the present invention

[0015] figure 1 Among them, one end of the arterial blood line tube (1) is connected with the arterial blood vessel, and the other end is connected with the plasma separator (4) through the heparin pump (2) and the blood pump (3), and the plasma separator (4) is connected through the plasma pump (6) ) and the circulation pipeline (7) are connected with two parallel adsorbers (8) and adsorbers (9), and then connected with the circulation pipeline (10) and the venous pipeline (5) in turn, and the venous pipeline (5) The other end is connected to the ...

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Abstract

The invention relates to an adsorption herapeutic apparatus for maternal-fetal blood group incompatibility, relating to the medical field. The apparatus is characterized by comprising following steps: utilizing PB of 25 and 35 mmol / L as lysate, fully washing Rh positive O-type erythrocytes and cleaning them with normal saline to make ghost cells with dialysis of ferrohemoglobin and antigen performance capable of effectively absorbing Rh antibodies, utilizing 0.9%, 1.0%, 1.1%, 1.2% and 1.3% of agarose which is melt at 100 DEG C and kept in 56 DEG C to make adsorbents of 95% of ghost cell concentration, orderly taking 55-65ml according to ghost cell concentration from high to low to be added into a cylindrical container made by material with high biocompatibility so that an absorber enabling adsorbents from a sample inlet end to a sample outlet end to form uniform distribution of ghost cells and agarose concentration from low to high, using the above to clear Rh anti-bodies in plasmas filtered by the absorber and macromolecule disease-causing substances generated by destroyed erythrocyte such that the treatment purpose of preventing Rh anti-bodies of pregnant women from entering fetus blood and lightening condition is achieved.

Description

technical field [0001] The invention relates to an adsorption therapeutic apparatus for maternal-fetal blood group incompatibility in the medical field, which is mainly used for removing anti-fetal red blood cell antibodies and red blood cell lysates in plasma of pregnant women with maternal-fetal blood group incompatibility. Background technique [0002] The fetus inherits half of the genetic components of the father and half of the mother, and the fetal red blood cells can carry antigens from the father, showing that the blood type of the fetus is different from that of the mother. When the fetal red blood cells enter the mother's blood circulation, the mother's immune system is induced to produce antibodies, and the antibodies pass through the placenta and enter the fetal blood circulation system, combining with fetal red blood cells, causing fetal red blood cells to be destroyed, resulting in maternal-fetal blood group incompatibility hemolytic disease in fetuses and newb...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M1/36C12N5/078
CPCA61M1/362A61M1/3621A61M1/3633A61M1/3689A61M2202/0413A61M2202/0429A61M2205/02A61M2210/12C12N5/0634A61M2202/0021A61M2202/0064
Inventor 翁炳焕李兰娟
Owner ATTACHED OBSTETRICS & GYNECOLOGY OSPITAL MEDICALCOLLEGE ZHEJIANG UNIV
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