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Micro simply supported beam apparatus for weighing mass of DNA molecules

A technology of DNA molecules and simply supported beams, applied in the field of detection and weighing of organic macromolecules, can solve problems such as difficult to measure the mass accurately, and achieve the effect of high measurement accuracy

Inactive Publication Date: 2016-11-16
CHANGZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, DNA molecules are smaller than macroscopic objects, and its mass is difficult to measure accurately. Therefore, it is of practical value to design a device that can quickly and accurately detect the mass of DNA molecules

Method used

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  • Micro simply supported beam apparatus for weighing mass of DNA molecules
  • Micro simply supported beam apparatus for weighing mass of DNA molecules

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Embodiment Construction

[0012] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0013] see figure 1 and figure 2 As shown, a micro-simply-supported beam device for weighing the molecular mass of DNA of the present invention includes a fixed hinge 11, a movable hinge 12, and a composite micro-simply-supported beam whose two ends are respectively installed on the fixed hinge 11 and the movable hinge 12. The beam, the DNA molecular module 3 to be weighed, and the micro-strain sensor 4 installed on the bottom surface of the middle part of the composite micro simply supported beam; the composite micro simply supported beam includes an upper stack 21, a lower stack 22, and a connecting upper stack 21 and the non-slip surface 20 of the lower stack 22; the middle part of the upper stack 21 has a DNA pit 23, and the DNA pit 23 can be placed with a DNA molecular module 3; the inspection accuracy of the micro-strain senso...

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Abstract

The invention discloses a micro simply supported beam apparatus for weighing a mass of DNA molecules and belongs to the field of organic macro-molecule mass detection and weighing. The apparatus comprises a fixed hinge, a movable hinge, a composite simply supported beam whose two ends are respectively arranged on the fixed hinge and the movable hinge, a DNA molecule module to be weighed, and a micro strain sensor arranged at the bottom surface of the central portion of the composite simply supported beam, wherein the composite simply supported beam comprises an upper lamination, lower lamination and a slip-free surface connecting the upper lamination with the lower lamination. The micro simply supported beam apparatus is remarkable in bending deformation and can accurately measure the mass of the DNA molecules.

Description

technical field [0001] The invention mainly relates to the field of detection and weighing of organic macromolecular mass, in particular to a micro simply supported beam device for weighing DNA molecular mass. Background technique [0002] It is of great significance to quickly and accurately measure the quality of DNA molecules, because DNA molecules are the main component of chromosomes and also the main genetic material. The infection of various human diseases can be reflected in the corresponding DNA molecular structure and quality. However, DNA molecules are smaller than macroscopic objects, and its mass is difficult to measure accurately. Therefore, it is of practical value to design a device that can quickly and accurately detect the mass of DNA molecules. Contents of the invention [0003] The technical problem to be solved in the present invention is: aiming at the technical problems existing in the prior art, the present invention provides a micro simply support...

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Application Information

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IPC IPC(8): G01G3/12G01N5/00
CPCG01G3/12G01N5/00
Inventor 班书昊李晓艳蒋学东何云松席仁强徐然谭邹卿
Owner CHANGZHOU UNIV