Visual fatigue alleviating pharmaceutical combination preparation and preparation method thereof

A technology of eye fatigue and composition, which is applied in the field of medicine, can solve the problems of different powers of eye fatigue and other problems, and achieve the effect of improving eye pain, high content of active ingredients, and refined formula

Inactive Publication Date: 2017-01-04
ZHEJIANG ASEN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the prescriptions published by these two patent applications all contain the same three main ingredients as the present invention, they contain other ingredients, and the prepared dosage forms have different effects on relieving visual fatigue.

Method used

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  • Visual fatigue alleviating pharmaceutical combination preparation and preparation method thereof
  • Visual fatigue alleviating pharmaceutical combination preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Party:

[0087] Capsule core: bilberry extract 142g, lutein 77g, β-carotene 19g, corn oil 255g, beeswax 15g;

[0088] Capsule skin: 140g gelatin, 56g glycerin, 133g purified water, 0.5g titanium dioxide, 1.2g monascus red, 1.0g caramel color;

[0089] Preparation:

[0090] In step a, take the bilberry extract and pass it through an 80-mesh sieve, and set aside; take beeswax and corn oil, heat to 70°C to melt the beeswax, stir and mix well to obtain a mixed material, put it at room temperature, and set aside; take the lingonberry extract, leaf yellow Add β-carotene and β-carotene to the mixture, stir and mix well, pass through a colloid mill to grind into a fine slurry, leave it to vacuumize -0.06~-0.08Mpa until there are no bubbles, and set aside;

[0091] Step b, when the purified water is heated to 60°C, add gelatin, glycerin, titanium dioxide, monascus red, caramel color, cover and seal, start the stirring paddle to stir, and heat to 70°C, stir to make it a uniform...

Embodiment 2

[0094] Party:

[0095] Capsule core: bilberry extract 130g, lutein 68g, β-carotene 12g, corn oil 267g, beeswax 14g;

[0096] Capsule skin: 140g gelatin, 56g glycerin, 133g purified water, 0.5g titanium dioxide, 1.2g monascus red, 1.0g caramel color;

[0097] Preparation:

[0098] Step a, take the bilberry extract and pass it through a 100-mesh sieve, and set aside; take beeswax and corn oil, heat to 70°C to melt the beeswax, stir and mix well to obtain the mixed material, put it at room temperature, and set aside; take the lingonberry extract, leaf yellow Add β-carotene and β-carotene to the mixture, stir and mix well, pass through a colloid mill to grind into a fine slurry, leave it to vacuumize -0.06~-0.08Mpa until there are no bubbles, and set aside;

[0099] Step b, when the purified water is heated to 60°C, add gelatin, glycerin, titanium dioxide, monascus red, and caramel color, cover and seal, start the stirring paddle to stir, and heat to 70°C, stir to make it a unif...

Embodiment 3

[0102] Capsule core: bilberry extract 93g, lutein 38g, β-carotene 5g, corn oil 360g, beeswax 8g;

[0103] Capsule skin gelatin 140g, glycerin 56g, purified water 133g, titanium dioxide 0.5g, monascus red 1.2g, caramel color 1.0g;

[0104] Preparation method: with embodiment 1.

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PUM

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Abstract

The present invention provides a visual fatigue alleviating pharmaceutical combination preparation and a preparation method thereof, wherein the visual fatigue alleviating pharmaceutical combination preparation comprises a capsule skin and a capsule core, and is characterized in that the capsule core is prepared from the following raw materials by weight: 80-200 parts of a vaccinium extract, 20-100 parts of lutein, 5-30 parts of beta-carotene, 200-400 parts of vegetable oil, and 5-20 parts of beeswax. The visual fatigue alleviating pharmaceutical combination preparation of the present invention has advantages of refined prescription, high effective component content and effective improvement of clinical symptoms such as eye pain, eye swelling, photophobia, blurred vision, dry eye and the like, and provides effects superior to the composition in the prior art.

Description

technical field [0001] The invention relates to a pharmaceutical composition preparation and a preparation method thereof, in particular to a pharmaceutical composition preparation for relieving visual fatigue and a preparation method thereof, belonging to the field of medicine. Background technique [0002] Visual fatigue generally refers to the syndrome of subjective symptoms produced when working with the eyes, mainly manifested as visual impairment, such as blurred vision, ghosting, overlapping words, and jumping words when using the eyes at close range; It takes a moment to gradually see clearly. Eye symptoms include eye sleepiness, photophobia, heavy eyelids, difficulty opening eyes, soreness or pain around the eyeballs and orbits, tearing, foreign body sensation, dry eyes, and twitching eyelids. [0003] In recent years, with the acceleration of the pace of work, study, and life, the load on the eyes has increased, and the number of patients with visual fatigue has g...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/45A61K9/48A61P27/10A61K31/047A61K31/015
Inventor 邓金明吴海英钟若曦泮江武
Owner ZHEJIANG ASEN PHARMA
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