A nanotube-based fluorescent labeling carrier and its preparation method

Abstract

The invention discloses a nanotube-based fluorescence marked carrier and a preparation method thereof. The fluorescence marked carrier comprises a nanotube inner wall, a quantum structure and a nanotube outer wall. The size of the nanotube structure is designed according to the characteristics of a simulated carrying object, and the size of the nanotube structure is regulated and controlled accurately by controlling the growth condition; in the fixed-temperature annealing process, a nanowire in a core-shell structure is guaranteed to be decomposed completely and the quantum structure limited between the nanotube inner wall and the nanotube outer wall is not damaged; the fluorescence marked part of the nanotube adopts a semiconductor quantum structure, has high fluorescence intensity, long duration time and stable photochemical property, is insusceptible to photobleaching and realizes high-efficiency radiative recombination; furthermore, continuous broad spectrum excitation can be adopted, the absorption coefficient is big, fluorescence emission peak is narrow, wavelength trailing is avoided, and the distinguishing degree is high; the nanotube structure can realize fluorescence marked carrying of the carrying object in the tube and also can perform the traditional wrapping or combined type fluorescence marked carrying.

Description

technical field [0001] The invention relates to a method for preparing a fluorescent labeling carrier, in particular to a method for preparing a nanotube-based fluorescent labeling carrier. Background technique [0002] Fluorescent labeling technology originated in the 1940s and was first used to label antibodies to detect corresponding antigens. With the advancement of science and technology and the development of biomedicine, materials science and other fields, targeted detection and targeted therapy at the cell scale or molecular and atomic scales have become a major issue in many disciplines and fields such as medicine, biology, chemistry and materials science. As one of the research goals of the research, the labelable and non-destructive delivery of drugs and reagents is a key issue for the realization of precision medicine and precise detection. The traditional fluorescent labeling method mainly uses chemical reagents that have fluorescent properties or can produce f...

AI Technical Summary

Problems solved by technology

[0003] Existing nanotubes are mainly obtained by chemical synthesis methods, and the size (diameter, length and wall thickness) of nanotubes is difficult to precisely control

In addition, due to the limitations of materials and structures, existing nanotube materials have technical bottlenecks such as non-luminescence, low luminous efficiency, or non-adjustable luminous wavelength.

The above technical difficulties make it difficult to prepare nanotubes for specific wavelengths and specific sizes

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