A kind of compound medicine with promoting immune function and preparation method thereof

An immune function and compound technology, which is applied in the field of compound drugs with immune function and its preparation, can solve the problems of low immunity, aggravated liver and kidney metabolic load, easy drug resistance, etc., and achieves simple process and high extraction rate High and enhance the body's immunity

Active Publication Date: 2020-12-08
LANZHOU UNIVERSITY
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AI Technical Summary

Problems solved by technology

[0002] With the gradual increase of people's living pressure and the gradual deterioration of living environment, the vast majority of people are in a sub-health state, which is mainly manifested as low immunity and weak defense against various viruses and bacteria, and long-term use of antibiotic chemical synthetic drugs , prone to drug resistance, is not conducive to human health
[0003] At present, although many types of immune enhancers have appeared on the market, the active substances of these products are either traditional Chinese medicine compositions with complex components, and long-term consumption will increase the metabolic load on the liver and kidneys; or they are compounds with a single component. Its ability to improve human immune function is limited, and long-term consumption is prone to drug resistance

Method used

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  • A kind of compound medicine with promoting immune function and preparation method thereof
  • A kind of compound medicine with promoting immune function and preparation method thereof
  • A kind of compound medicine with promoting immune function and preparation method thereof

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preparation example Construction

[0025] This embodiment also provides a preparation method of a compound drug with an immune-promoting function, which includes:

[0026] S1: Mix the raw materials in parts by weight, and extract the mixture of raw materials by solvent extraction to obtain a medicinal solution.

[0027] Further, the solvent extraction method includes any one of decoction method, percolation method, heating reflux method, and microwave extraction method. The solvent used in the extraction is water or ethanol, or a mixture of water and alcohol. When the heating and reflux method is used for extraction, preferably, the mixture of raw materials is refluxed at 60-80°C for 1-3 times for 1-3 hours each time, and then the obtained extracts are combined to obtain a drug solution.

[0028] The solvent extraction method is a decoction method, and the decoction method includes: soaking the mixture of raw materials in water for 1-2 hours, heating and boiling to obtain the extract; decocting 2-3 times in to...

Embodiment 1

[0037] This embodiment provides a kind of compound medicine that has the function of promoting immunity, and the crude drug of this compound medicine comprises:

[0038] Codonopsis 300g, hawthorn 300g, wolfberry 150g.

[0039] The preparation method of this compound medicine is:

[0040] Mix the above-mentioned Codonopsis pilosula, hawthorn and wolfberry, soak them in water for 1.5 hours, heat and boil to obtain an extract; decoct 3 times in total, each time is 1.5 hours, and the amount of water in each decoction is respectively 12 times, 10 times and 10 times the total mass of Lycium barbarum; then the obtained extracts are combined to obtain a medicinal solution.

[0041] Then the liquid was concentrated under reduced pressure at 70°C to a relative density of 0.18g / mL to obtain a concentrated liquid, which was then centrifuged to obtain a supernatant, and then the supernatant was mixed with steviol glycosides and potassium sorbate to obtain 400 mL of Oral solution.

Embodiment 2

[0043] This embodiment provides a kind of compound medicine that has the function of promoting immunity, and the crude drug of this compound medicine comprises:

[0044] Codonopsis 500g, hawthorn 500g, wolfberry 300g.

[0045] The preparation method of this compound medicine is:

[0046] Dried Codonopsis pilosula, hawthorn and wolfberry were dried and crushed to 4-20 meshes, mixed, soaked in water for 1 hour, heated and boiled to obtain the extract; decocted for 2 times, each decocting time was 2 hours, each time decocting The amount of water is 12 times of the total mass of Codonopsis pilosula, hawthorn and wolfberry; then the obtained extracts are combined to obtain a medicinal solution.

[0047] Then the liquid was concentrated under reduced pressure at 80°C to a relative density of 0.2g / mL to obtain a concentrated liquid, which was then centrifuged to obtain a supernatant, and then the supernatant was mixed with steviol glycosides and potassium sorbate to obtain 700 mL of ...

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Abstract

The invention provides a compound medicine with a function of promoting immunity and a preparation method thereof and belongs to the field of medicine preparations. The compound medicine comprises the following crude drugs in parts by weight: 3-5 parts of codonopsis pilosula, 3-5 parts of hawthorns and 1-3 parts of wolfberries. The compound medicine has the functions of generating blood, enhancing immunity of the body and reducing the blood pressure and can be used for improving the sub-health status of hypoimmunity of the body and disordered qi and blood, yin and yang and viscera. The preparation method for the compound medicine comprises the following steps: mixing the crude drugs in parts by weight; adopting a solvent extraction method for extracting the mixture of the crude drugs; and preparing the obtained liquid medicine into different forms of drugs. According to the preparation method, the solvent extraction method is adopted for extracting the crude drugs; the extraction ratio of the effective constituents in the crude drugs is high; the process is simple; and the method is suitable for large-scale production.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a compound medicine with the function of promoting immunity and a preparation method thereof. Background technique [0002] With the gradual increase of people's living pressure and the gradual deterioration of living environment, the vast majority of people are in a sub-health state, which is mainly manifested as low immunity and weak defense against various viruses and bacteria, and long-term use of antibiotic chemical synthetic drugs , prone to drug resistance, is not conducive to human health. [0003] At present, although many types of immune enhancers have appeared on the market, the active substances of these products are either traditional Chinese medicine compositions with complex components, and long-term consumption will increase the metabolic load on the liver and kidneys; or they are compounds with a single component. Its ability to improve human immune fu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P37/04A61P7/06A61P9/12
CPCA61K36/344A61K36/734A61K36/815A61K2236/15A61K2236/17A61K2236/331A61K2236/39A61K2300/00
Inventor 胡芳弟苟于强马玉玲白瑞斌孙伯禄
Owner LANZHOU UNIVERSITY
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