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Method and system for online monitoring content of creatinine in dialysate of hemodialysis

A technology of dialysis fluid and monitoring system, which is applied in measuring devices, analyzing materials, and analyzing materials through optical means. It can solve undiscovered problems, reduce human error and system error, shorten detection time, and prevent medical accidents. Effect

Active Publication Date: 2017-07-04
SHANGHAI UNIV OF MEDICINE & HEALTH SCI +1
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Problems solved by technology

However, the literature search did not find its application in the field of hemodialysis online monitoring

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  • Method and system for online monitoring content of creatinine in dialysate of hemodialysis
  • Method and system for online monitoring content of creatinine in dialysate of hemodialysis

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Embodiment Construction

[0036] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0037] A method for on-line monitoring of creatinine content in hemodialysate, the method comprising the steps of:

[0038] 1) Prepare hemodialysate samples with different creatinine contents, and the number of samples meets the requirements for establishing a sample inspection model;

[0039] 2) Using a near-infrared spectrometer to collect the spectrum of the dialysate sample;

[0040] 3) Establish a quantitative identification model for creatinine content in hemodialysis fluid based on near-infrared spectroscopy;

[0041] 4) Use the on-line monitoring probe to collect near-infrared spectrum of the dialysate at the outlet of the hemodialyzer, and perform a quantitative identification model for the creatinine content in the dialysate at the dialysate outlet of the collected near-infrared spectrum with the creatinine content in the dialysate e...

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Abstract

The invention relates to a method and system for online monitoring the content of creatinine in dialysate of hemodialysis. According to the method, a dialysate sample examination model is established by adopting near-infrared spectroscopy, the change of content of creatinine in dialysate is online monitored, on the basis of the change rule of creatinine in dialysate of hemodialysis, the creatinine content can be monitored so as to prevent and avoid accidents in hemodialysis; scientific references are provided for the treatment of patients with uremia, and the kidney disease treatment level is improved.

Description

technical field [0001] The invention relates to an online monitoring method and system for creatinine content in hemodialysis fluid, in particular to an online monitoring method and system for creatinine content in hemodialysis fluid using near-infrared spectrum detection. Background technique [0002] At present, blood purification is widely required in clinical treatment. Taking dialysis treatment of kidney disease as an example, there are about 2 million patients with end-stage renal disease in my country, 400,000 of whom are receiving hemodialysis treatment, which is increasing at a rate of more than 10% every year. Patients have a great demand for dialysis treatment. [0003] Hemodialysis uses the principle of semi-permeable membrane to introduce the patient's blood and dialysate into the inner and outer sides of the dialyzer at the same time. With the help of the solute gradient, osmotic gradient and diffusivity on both sides of the membrane, through diffusion, convect...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/359G01N21/3577
CPCG01N21/3577G01N21/359
Inventor 黄钢王海波杨培强徐军胡兆燕
Owner SHANGHAI UNIV OF MEDICINE & HEALTH SCI
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