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Online monitoring method and system for content of urea nitrogen and creatinine in hemodialysis liquid

A technology of urea nitrogen creatinine and dialysate dialysis fluid is applied in the field of online monitoring of urea nitrogen creatinine content in hemodialysis dialysate, which can solve problems such as undiscovered, and achieve the reduction of human error and system error, rapid non-destructive testing, and short testing time. Effect

Active Publication Date: 2017-07-28
SHANGHAI UNIV OF MEDICINE & HEALTH SCI +1
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Problems solved by technology

However, the literature search did not find its application in the field of hemodialysis online monitoring

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  • Online monitoring method and system for content of urea nitrogen and creatinine in hemodialysis liquid
  • Online monitoring method and system for content of urea nitrogen and creatinine in hemodialysis liquid

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Embodiment Construction

[0037] The present invention will be further described below in conjunction with the drawings and specific embodiments.

[0038] An online monitoring method for the content of urea nitrogen and creatinine in hemodialysis dialysis solution includes the following steps:

[0039] 1) Prepare hemodialysis samples with different urea nitrogen content and creatinine content, and the number of samples meets the requirements for establishing a sample inspection model;

[0040] 2) Use near-infrared spectrometer to collect spectrum of hemodialysis fluid samples with urea nitrogen content and creatinine content;

[0041] 3) Establish a quantitative identification model of urea nitrogen content and creatinine content in hemodialysis dialysate based on near-infrared spectroscopy;

[0042] 4) Use the online monitoring probe to collect the near-infrared spectrum of the dialysate at the outlet of the hemodialysis dialyzer, and combine the collected near-infrared spectra of the urea nitrogen content and ...

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Abstract

The invention relates to an online monitoring method and an online monitoring system for the content of urea nitrogen and creatinine in a hemodialysis liquid. A dialysate sample test model is built by adopting a near infrared spectrometer, the content changes of the urea nitrogen and the creatinine in the hemodialysis liquid are monitored online and a hemodialysis accident is monitored, prevented and avoided according to the content changes of the urea nitrogen and the creatinine in the hemodialysis liquid, thereby providing a scientific basis for treatment of uremia patients and achieving the target of improving the kidney disease treatment level.

Description

Technical field [0001] The invention relates to an online monitoring method and system for the content of urea nitrogen and creatinine in a hemodialysis dialysis solution, in particular to an online monitoring method and system for the content of urea nitrogen and creatinine in the hemodialysis dialysis solution using near infrared spectroscopy. Background technique [0002] Currently, blood purification is widely needed in clinical treatment. Take dialysis treatment for kidney disease as an example. There are about 2 million end-stage renal disease patients in my country, 400,000 are receiving hemodialysis treatment, which is increasing at a rate of more than 10% every year, and patients have a great demand for dialysis treatment. [0003] Hemodialysis therapy uses the principle of a semi-permeable membrane to introduce the patient’s blood and dialysate into the inside and outside of the dialyzer at the same time. With the help of solute gradients, osmotic gradients and dispersion...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/359G01N21/3577
CPCG01N21/3577G01N21/359
Inventor 黄钢王海波杨培强徐军胡兆燕
Owner SHANGHAI UNIV OF MEDICINE & HEALTH SCI
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