Vitamin ADE microemulsion injecta for veterinary use and preparation method of vitamin ADE microemulsion injecta

Abstract

The invention belongs to the field of veterinary drug preparations, particularly belongs to the technical field of fat-soluble vitamin injection and relates to vitamin ADE microemulsion injecta for veterinary use and a preparation method of the vitamin ADE microemulsion injecta. The vitamin ADE microemulsion injecta for the veterinary use is prepared from the following raw materials in parts by weight: 5 to 10 parts of vitamin A palmitate, 0.1 to 1 part of vitamin D 3 oil, 20 to 50 parts of vitamin E acetate, 0.5 to 1 part of BHA (Butylated Hydroxyanisole), 0.5 to 1 part of BHT (Butylated Hydroxytoluene), 1 to 2 parts of phenylcarbinol, 2 to 10 parts of Tween 80, 10 to 30 parts of absolute ethyl alcohol and 10 to 60 parts of soybean oil for injection. The invention also provides the preparation method of the injecta. According to the preparation method of the vitamin ADE microemulsion injecta, disclosed by the invention, vitamin A, vitamin D and vitamin E are compounded for use; the latest international recommended dose of vitamin is used as the basis of the content of a main drug, grease is selected as a solvent according to the solubility property of the vitamin and is compounded with a certain amount of a surfactant and a cosurfactant, and thus a clear vitamin ADE injecta is obtained; the hydrophilicity and the dispersibility of the product are increased, rapid absorption of an organism is facilitated and the bioavailability is improved.

Description

technical field [0001] The invention belongs to the field of veterinary drug preparations, in particular to the technical field of fat-soluble vitamin injections, and relates to veterinary vitamin ADE microemulsion injections and a preparation method thereof. Background technique [0002] Although vitamins are not energy substances, nor are they the raw materials of tissues or organs, they play an important role in the normal progress of substance metabolism in the body, the transformation of energy and the maintenance of physiological functions. Vitamin A, vitamin D, and vitamin E are all fat-soluble vitamins. Vitamin A can not only maintain normal vision, maintain the integrity of epithelial cells and promote normal bone development, improve immunity, inhibit tumors, but also contribute to the normal metabolism of the body. Vitamin D is an essential nutrient for maintaining the life of higher animals and one of the most important regulators of calcium and phosphorus metab...

AI Technical Summary

Problems solved by technology

The prescription ingredients of multivitamin drugs are complicated, and there are direct or indirect interactions between the components, and the stability is poor

Images