Tooth remineralization toothpaste and preparation method thereof

A remineralization and toothpaste technology, applied in the field of oral care, can solve the problems of reducing the excitability of nerve fiber endings, not inducing enamel remineralization, and not sealing dentine tubules, so as to improve dental caries, promote deposition, and eliminate allergies The effect of symptoms

Inactive Publication Date: 2017-09-15
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, compared with the effect of fluoride, strontium chloride cannot induce the remineralization of tooth enamel, and it can only play a "palliative, not a permanent" effect on dentin hypersensitivity
However, other types of desensitizers, such as potassium nitrate-containing compositions, can only reduce the excitability of nerve fiber endings and relieve pain in a short period of time, but do not fundamentally seal the exposed dentinal tubules and prevent tooth decay. Enamel demineralization

Method used

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  • Tooth remineralization toothpaste and preparation method thereof
  • Tooth remineralization toothpaste and preparation method thereof
  • Tooth remineralization toothpaste and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0031] The present embodiment provides a toothpaste for tooth remineralization, comprising the following raw material components in percentage by weight: 3% of wollastonite microspheres with a diameter of 2.0 μm, 20% of silicon dioxide, 0.5% of polysorbate 20, and 20% of glycerin , sodium carboxymethylcellulose 1%, and the rest is distilled water.

[0032] The preparation method of above-mentioned toothpaste comprises the following steps:

[0033] Step 1, adding sodium carboxymethyl cellulose to glycerin, stirring and mixing evenly to obtain mixture A;

[0034] Step 2, dissolve wollastonite microspheres and polysorbate 20 in distilled water, stir and mix evenly to obtain mixture B; wherein, the diameter of wollastonite microspheres is 2.0 μm, and proceed as follows: take natural wollastonite , respectively with deionized water and absolute ethanol under the condition of 3000rpm centrifugal washing 3 times, placed in a 60 ° C oven to dry, using a corundum mortar to grind natur...

Embodiment 2

[0037] The present embodiment provides a toothpaste for tooth remineralization, comprising the following raw material components in percentage by weight: 5% of wollastonite microspheres with a diameter of 2.0 μm, 20% of silicon dioxide, 0.5% of polysorbate 20, and 20% of glycerin , sodium carboxymethylcellulose 1%, and the rest is distilled water.

[0038] The preparation method of above-mentioned toothpaste comprises the following steps:

[0039] Step 1, adding sodium carboxymethyl cellulose to glycerin, stirring and mixing evenly to obtain mixture A;

[0040] Step 2, dissolving wollastonite microspheres and polysorbate 20 in distilled water, stirring and mixing uniformly to obtain mixture B; wherein, the diameter of wollastonite microspheres is 2.0 μm, and its preparation method is the same as in Example 1;

[0041] Step 3: mix mixture A and mixture B uniformly, add silicon dioxide, stir to obtain a uniform colloid, vacuum degass, and sterilize to obtain.

Embodiment 3

[0043] The present embodiment provides a tooth remineralization toothpaste, which comprises the following raw material components in percentage by weight: 4% of wollastonite microspheres with a diameter of 2.0 μm, 40% of silicon dioxide, 2% of Polyoxamer407, 40% of glycerin, carboxymethyl Base cellulose sodium 3%, the rest is distilled water.

[0044] The preparation method of above-mentioned toothpaste comprises the following steps:

[0045] Step 1, adding sodium carboxymethylcellulose into glycerin, stirring and mixing evenly to obtain mixture A;

[0046] Step 2, dissolving wollastonite microspheres and polysorbate 20 in distilled water, stirring and mixing uniformly to obtain mixture B; wherein, the diameter of wollastonite microspheres is 2.0 μm, and its preparation method is the same as in Example 1;

[0047] Step 3: mix mixture A and mixture B uniformly, add silicon dioxide, stir to obtain a uniform colloid, vacuum degass, and sterilize to obtain.

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Abstract

The invention belongs to the technical field of oral cavity nursing and particularly relates to tooth remineralization toothpaste. The tooth remineralization toothpaste contains the following raw material components in percentage by weight: 3%-5% of wollastonite, 20%-60% of an abrasive, 0.5%-2% of a cleaning agent, 20%-40% of a wetting agent, 1%-5% of an adhesive and the balance of water. A preparation method of the tooth remineralization toothpaste comprises the following steps: firstly adding the adhesive into the wetting agent, and uniformly stirring and mixing, so as to obtain a mixture A; dissolving the wollastonite and the cleaning agent into water, and uniformly stirring and mixing, so as to obtain a mixture B; and uniformly mixing the mixture A with the mixture B, adding the adhesive, and uniformly stirring, so as to obtain the tooth remineralization toothpaste. The tooth remineralization toothpaste simultaneously has the efficacies of blocking dentinal tubules and inducing remineralization of enamel, so that decayed teeth can be effectively improved, and the hypersensitive dentin symptom can be fundamentally eliminated.

Description

technical field [0001] The invention relates to the technical field of oral care, in particular to a tooth remineralization toothpaste and a preparation method thereof. Background technique [0002] Teeth are important chewing organs of human beings, and they have the function of assisting pronunciation and maintaining a beautiful appearance. The main body of the tooth is the dentin structure, which contains many regularly arranged dentin tubules, and there are nerve fibers in the tubes, which can sense external stimuli. The enamel covering the outside of the dentin is the hardest calcified tissue in the human body. It mainly contains inorganic salts such as calcium phosphate. This tissue can effectively block external stimuli such as cold, heat, and acid, and play a role in protecting teeth. When dental caries occurs or due to other factors (such as enamel hypoplasia, severe unilateral tooth wear, etc.), the enamel is destroyed and the dentin is exposed. The nerve fibers i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/25A61Q11/00A61K33/06A61P1/02A61P37/08
CPCA61K8/25A61K33/06A61K2800/28A61K2800/412A61Q11/00
Inventor 孔亮刘富伟许珊珊秦东泽梁建飞郝英胡奥郭威孝蒋威张凯李云鹏
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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