Nano-liposome sunscreen emulsion and preparation method thereof

A technology of nano-liposome and sunscreen lotion, which can be used in pharmaceutical formulations, cosmetic preparations, toiletry preparations, etc., which can solve problems such as inconvenient use and safety risks, and achieve improved skin conditions, good stability, and bioavailability Improved effect

Active Publication Date: 2017-09-15
ZHEJIANG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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  • Nano-liposome sunscreen emulsion and preparation method thereof
  • Nano-liposome sunscreen emulsion and preparation method thereof
  • Nano-liposome sunscreen emulsion and preparation method thereof

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Embodiment 1

[0041] (1) Take fresh and dried Sophora japonica and crush it to a powder with an average particle size of 60 mesh, add 20 times of ethanol to heat and reflux for extraction for 2 hours, filter while it is hot to remove solid impurities to obtain a filtrate, and the filtrate is concentrated to the original volume by a rotary evaporator The crude product was obtained by cooling and crystallization. The crude product was re-dissolved in 5 times (w / v) hot ethanol (50°C), centrifuged at 8000r / min for 10 minutes at high speed, the supernatant was taken, concentrated and crystallized by rotary evaporation, and repeated 3 times to obtain the refined Sophora japonica extract. Take Scutellaria baicalensis root and grind it to an average particle size of 30 mesh, add 0.05wt% neutral cellulase (150,000 u / g, Ningxia Hersbit Biotechnology Co., Ltd.) and 10 times the volume of water according to the mass of the raw material, and heat to 50°C to enzymatically Solution 1.5h. Filter the filt...

Embodiment 2

[0047] (1) Take fresh and dried Sophora japonica and crush it to a powder with an average particle size of 60 mesh, add 20 times of ethanol to heat and reflux for extraction for 2 hours, filter while it is hot to remove solid impurities to obtain a filtrate, and the filtrate is concentrated to the original volume by a rotary evaporator The crude product was obtained by cooling and crystallization. The crude product was re-dissolved in 5 times (w / v) hot ethanol (50°C), centrifuged at 8000r / min for 10 minutes at high speed, the supernatant was taken, concentrated and crystallized by rotary evaporation, and repeated 3 times to obtain the refined Sophora japonica extract. Take Scutellaria baicalensis root and grind it to an average particle size of 30 mesh, add 0.05wt% neutral cellulase (150,000 u / g, Ningxia Hersbit Biotechnology Co., Ltd.) and 10 times the volume of water according to the mass of the raw material, and heat to 50°C to enzymatically Solution 1.5h. Filter the filt...

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Abstract

The invention discloses nano-liposome sunscreen emulsion and a preparation method thereof. The nano-liposome sunscreen emulsion is prepared from, in weight percentage, 1-3wt% of cosmetic substrates, 1-3wt% of moisturizing factor base materials, 10-20wt% of moisturizers, 2-5wt% of compound extracts of sophora flower bud and Baikal skullcap roots, 10-20wt% of lipids, 1-3wt% of seaweed extracts, 0.01-0.1wt% of antioxidants and 5-10wt% of solubilizing agents and the rest deionized water. The nano-liposome sunscreen emulsion has good sunscreen effect and stability.

Description

(1) Technical field: [0001] The invention belongs to the field of chemical and daily chemical products, and relates to a sunscreen lotion, in particular to a nano liposome sunscreen lotion and a preparation method thereof. (2) Technical background: [0002] Sunlight is composed of continuous electromagnetic waves, which are divided into ultraviolet region, visible region and infrared region. The sunburn caused by skin exposure to sunlight radiation is mainly caused by ultraviolet rays (UV). Erythema often occurs when the skin is sunburned, and when it is severe, it is accompanied by phenomena such as edema, blisters, and peeling. The penetrability of UV rays to the skin varies, leading to different biological effects, and short-wave germicidal ultraviolet light (UVC), although having the highest energy, is mostly absorbed by stratospheric ozone. What really cause skin sunburn are long-wave dark spot effect ultraviolet (UVA) and medium-wave erythema effect ultraviolet (UVB)....

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/9706A61K8/14A61K8/73A61Q17/04
CPCA61K8/14A61K8/73A61K8/97A61K2800/413A61K2800/81A61K2800/82A61Q17/04
Inventor 邵平严志鹏邱镪张皓雅蒋丽刚
Owner ZHEJIANG UNIV OF TECH
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