Flaky triangular silver nanoparticle antibacterial suspension as well as preparation method and application thereof

Abstract

The invention discloses flaky triangular silver nanoparticle antibacterial suspension as well as a preparation method and application thereof. According to the preparation method, silver nitrate is mainly used as a silver source, a surfactant, hydrogen peroxide and a reducing agent are sequentially added into the silver source, and the flaky triangular silver nanoparticle antibacterial suspension is prepared by using a one-step synthesis method. The method is simple, mild, environment-friendly, free from seed crystal, less in time consumption, low in energy consumption and easy in realization of large-scale production, and can be used for rapidly synthesizing flaky triangular silver nanoparticles (Ag-Tri) only by means of a one-step reaction. The flaky triangular silver nanoparticles synthesized by the method are small in size and good in dispersion degree, can be absorbed by bacteria and release silver ions, thus achieving effects of restraining and killing the bacteria and further being used as an antibacterial agent in antibacterial treatment. Furthermore, when the antibacterial suspension is irradiated by 808nm near infrared light, the conversion between light and heat can be realized by means of a surface plasma resonance effect, so that a photothermal effect occurs, and the structures of the bacteria are damaged; the flaky triangular silver nanoparticle antibacterial suspension has higher photothermal conversion efficiency, thus being used for antibacterial photothermal therapy (PTT) and being capable of effectively curing traumatic infection.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to a flaky triangular silver nanoparticle antibacterial suspension and a preparation method and application thereof. Background technique [0002] In life, there are all kinds of harmful bacteria, which bring various diseases to people. With the improvement of people's living standards, more and more attention has been paid to health and hygiene, and antibacterial materials and their products have increasingly attracted people's attention. Silver has strong antibacterial ability and broad-spectrum bactericidal effect, and it will not accumulate in the human body to cause toxicity. It has been used as an antibacterial active material long ago. The antibacterial agent with silver as the antibacterial active ingredient is an ideal safe and environment-friendly antibacterial agent. [0003] The bactericidal performance of traditional silver antibacterial agents is main...

AI Technical Summary

Problems solved by technology

The physical method has high requirements on instruments and equipment, and the production cost is expensive

Chemical methods often use hydrazine hydrate, formaldehyde, polyols, organic amines, etc. as reducing agents. Although these reducing agents have high activity, they are harmful to the environment, and the prepared nano-silver is prone to agglomeration

And a single external treatment method limits its curative effect

[0013] The results of searching domestic and foreign literature and patents on photothermal antibacterial treatment nano-platforms show that there is no report on the green preparation method and application of photothermal antibacterial treatment based on flake triangular silver nanoparticle suspension.

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