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Dentifrice composition

A dentifrice and composition technology, applied in the field of dentifrice compositions containing aluminum lactate, can solve the problems of aluminum metallic taste, poor stability, no mention, etc., achieve metallic taste suppression, excellent effect, Effect of pH drop inhibition

Inactive Publication Date: 2017-09-26
LION CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Aluminum lactate has the effect of narrowing and blocking dentinal tubules. Although it is effective for the prevention or treatment of dentin hypersensitivity, adding aluminum lactate to oral compositions will cause a decrease in pH over time. Demineralization of teeth or peeling of oral mucosa due to acidity has the problem of poor stability, and also has the problem of producing a metallic taste unique to aluminum
[0003] Regarding such problems, in Patent Document 1 (Japanese Patent Application Laid-Open No. 10-231237 ), it is proposed to prevent cloudiness and sedimentation and improve stability by adding sugar alcohol to a liquid oral composition containing aluminum lactate. Scheme, in Patent Document 2 (Japanese Patent Laid-Open No. 2013-119520), it is proposed to add anionic surfactants, specific water-soluble polymers to dentifrice compositions containing potassium nitrate and / or aluminum lactate Substance, propylene glycol alginate, a technical solution to improve storage stability (liquid separation stability) while ensuring sufficient foaming, but these patent documents do not mention pH changes over time

Method used

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  • Dentifrice composition
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Examples

Experimental program
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Embodiment

[0072] The following examples, comparative examples, and formulation examples are given to describe the present invention in detail, but the present invention is not limited to the following examples. In addition, in the following examples, % represents mass % unless otherwise specified.

[0073] [Example, comparative example]

[0074] The dentifrice composition (toothpaste) of the composition shown in Tables 1-3 was prepared by the usual method, and it evaluated by the following method. The results are recorded in Tables 1-3 together.

[0075] In addition, the pH of the dentifrice composition was adjusted to 7.0 at 25°C.

[0076]

[0077] (1) Evaluation method of dentinal tubule sealing effect

[0078] Based on the method of Pashley et al. (J.Dent.Res.57,187-193,1987), the liquid permeability of the dentinal tubules was measured, and the degree of sealing of the dentinal tubules by each dentifrice composition was evaluated .

[0079]Dentin blocks were excised from huma...

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Abstract

Provided is a dentifrice composition that exhibits an excellent effect of sealing dentinal fine tubules, effectively suppresses a lowering of pH, shows a controlled lowering of pH with the passage of time, gives a suppressed metallic taste and a good feeling in use and is appropriately usable for inhibiting dentinal hyperesthesia, the dentifrice composition comprising: (A) 0.01-5 mass% of aluminum lactate; (B) 0.01-5 mass% of a fused phosphate; and (C) 0.1-3 mass% of an alpha-olein sulfonic acid. Also provided is a method for suppressing a lowering of pH and expression of a metallic taste in the dentifrice composition. The method comprises blending a dentifrice composition containing 0.01-5 mass% of the component (A) with 0.01-5 mass% of the component (B) and 0.1-3 mass% of the component (C).

Description

technical field [0001] The present invention relates to an aluminum lactate-containing aluminum lactate suitable for suppressing hyperesthesia, which exhibits a high dentinal tubule sealing effect and is excellent in suppressing pH drop, suppresses pH drop over time, suppresses metallic taste, and has a good feeling of use. dentifrice composition. Background technique [0002] Aluminum lactate has the effect of narrowing and blocking dentinal tubules. Although it is effective for the prevention or treatment of dentin hypersensitivity, adding aluminum lactate to oral compositions will cause a decrease in pH over time. Demineralization of teeth and peeling of oral mucosa due to acidity have the problem of poor stability, and there is also a problem of a metallic taste peculiar to aluminum. [0003] Regarding such problems, in Patent Document 1 (Japanese Patent Application Laid-Open No. 10-231237 ), it is proposed to prevent cloudiness and sedimentation and improve stability b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/365A61K8/24A61K8/46A61Q11/00
CPCA61K8/24A61K8/365A61K8/46A61Q11/00A61K8/26
Inventor 深泽哲
Owner LION CORP
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