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Traditional Chinese medicinal preparation having wind and cold dispelling, muscle and tendon relaxing and blood circulation activating effects, and preparation method thereof

A technology for relaxing tendons and activating collaterals, dispelling wind and dispelling cold, applied to traditional Chinese medicine preparations for relaxing tendons and collaterals and its preparation, medicine and preparation thereof, in the field of dispelling wind and dispelling cold, can solve problems such as inability to satisfy, and achieve no production equipment and production cost. Low, low energy consumption effect

Inactive Publication Date: 2017-09-29
广西大海阳光药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

None of the above extraction methods can meet the requirement that the impurities in the extract of traditional Chinese medicine should be as little as possible during the preparation of dispersible tablets, so as to ensure the content of active ingredients in the preparation and the requirements of drug efficacy.

Method used

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  • Traditional Chinese medicinal preparation having wind and cold dispelling, muscle and tendon relaxing and blood circulation activating effects, and preparation method thereof
  • Traditional Chinese medicinal preparation having wind and cold dispelling, muscle and tendon relaxing and blood circulation activating effects, and preparation method thereof
  • Traditional Chinese medicinal preparation having wind and cold dispelling, muscle and tendon relaxing and blood circulation activating effects, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] A method for preparing a dispersible tablet from a traditional Chinese medicine preparation for expelling wind and cold, relaxing tendons and activating collaterals, comprising the steps of:

[0081] T1. Take the following components respectively: hydroxypropyl methylcellulose, pregelatinized starch, crospovidone, sodium lauryl sulfate, micropowder silica gel, pulverize through a 100-mesh sieve, and set aside;

[0082] T2. Weigh the components according to the following parts by weight: 600g of Aconitum japonica, 900g of Aconitum japonica, 1300g of Fangji, 600g of Fangfeng, 600g of Dipsacus, 600g of Achyranthes bidentata, 600g of cassia twig, 600g of clematis, 1300g of geranium, seaweed Sodium phosphate 500g, hydroxypropyl methylcellulose 200g, pregelatinized starch 700g, crospovidone 300g, sodium lauryl sulfate 100g, micronized silica gel 40g;

[0083] T3. Preparation of medicinal material extract dry paste powder: take the weighed medicinal materials and break them in...

Embodiment 2

[0089] A method for preparing a dispersible tablet from a traditional Chinese medicine preparation for expelling wind and cold, relaxing tendons and activating collaterals, comprising the steps of:

[0090] T1. Take the following components respectively: hydroxypropyl methylcellulose, pregelatinized starch, crospovidone, sodium lauryl sulfate, micropowder silica gel, pulverize through a 100-mesh sieve, and set aside;

[0091] T2. Weigh the components according to the following parts by weight: 800g of Aconitum japonica, 1100g of Aconitum japonica, 1500g of Fangji, 800g of Fangfeng, 800g of Dipsacus, 800g of Achyranthes bidentata, 800g of cassia twig, 800g of clematis, 1500g of geranium, seaweed 1000g of sodium lauryl sulfate, 400g of hydroxypropyl methylcellulose, 1500g of pregelatinized starch, 600g of crospovidone, 200g of sodium lauryl sulfate, and 60g of micronized silica gel;

[0092] T3. Preparation of medicinal material extract dry paste powder: take the weighed medicin...

Embodiment 3

[0098] A method for preparing a dispersible tablet from a traditional Chinese medicine preparation for expelling wind and cold, relaxing tendons and activating collaterals, comprising the steps of:

[0099] T1. Take the following components respectively: hydroxypropyl methylcellulose, pregelatinized starch, crospovidone, sodium lauryl sulfate, micropowder silica gel, pulverize through a 100-mesh sieve, and set aside;

[0100] T2. Weigh the components according to the following parts by weight: 680g of Zhichuan Aconitum, 1020g of Zhicaowu, 1360g of Fangji, 680g of Fangfeng, 680g of Dipsacus, 680g of Achyranthes bidentata, 680g of Guizhi, 680g of Clematis, 1360g of Geranium, seaweed 750g sodium phosphate, 300g hydroxypropyl methylcellulose, 1100g pregelatinized starch, 450g crospovidone, 150g sodium lauryl sulfate, 50g micronized silica gel;

[0101] T3. Preparation of medicinal material extract dry paste powder: take the weighed medicinal materials and break them into 9 mesh co...

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Abstract

The invention discloses a traditional Chinese medicinal preparation having wind and cold dispelling, muscle and tendon relaxing and blood circulation activating effects, and a preparation method thereof. The preparation comprises, by weight, 60-80 parts of Radix Aconiti Preparata, 90-110 parts of Radix Aconiti Kusnezoffii Preparata, 130-150 parts of Radix Stephaniae Tetrandrae, 60-80 parts of Divaricate Saposhnikovia Root, 60-80 parts of Himalayan Teasel Root, 60-80 parts of Achyranthes bidentata, 60-80 parts of cassia twig, 60-80 parts of Radix Clematidis, 130-150 parts of Geranium wilfordii Maxim., 50-100 parts of sodium alginate, 20-40 parts of hydroxypropyl methyl cellulose, 70-150 parts of pregelatinized starch, 30-60 parts of crospovidone, 10-20 parts of sodium dodecyl sulfate and 4-6 parts of aerosol. The preparation is processed to prepare a dispersing tablet. The preparation method is carried out to extract medicinal materials in order to prepare dry paste powder, the dry paste powder is processed to prepare a clathrate, and the clathrate is processed to the prepare the dispersing tablet. The above product obviously improves the dissolvability of insoluble medicines in the dry paste powder of the medicinal material extract, shortens the disintegration time and increases the bioavailability. The preparation method has the advantages of simple process, low production cost, low energy consumption, and easiness in realization of industrial production.

Description

technical field [0001] The invention belongs to the field of medicines, and relates to a medicine and a preparation method thereof, in particular to a traditional Chinese medicine preparation for expelling wind and cold, relaxing tendons and activating collaterals and a preparation method thereof. Background technique [0002] Fengshiling Tablets are recorded in the third volume of the Ministry of Health's Drug Standards for Traditional Chinese Medicine Prescriptions, and the standard number is WS 3 -B-0518-91, the prescription is: Zhichuanwu, Zhicaowu, Fangji, Guizhi, Dipsacus, Achyranthes bidentata, Fangfeng, Clematis, Geranium, in sugar-coated tablets. It has the functions of expelling wind and cold, relaxing tendons and activating collaterals, and is clinically used to treat wind-cold-damp arthralgia, joint pain, numbness of hands and feet, and soreness of waist and legs. [0003] Due to the existing preparation technology and other reasons, the sugar-coated tablets of ...

Claims

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Application Information

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IPC IPC(8): A61K36/716A61K9/20A61K47/69A61K47/61A61K47/36A61K47/38A61P29/00
CPCA61K9/2027A61K9/2054A61K9/2059A61K36/185A61K36/21A61K36/238A61K36/54A61K36/59A61K36/714A61K36/716A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 黄大权邓春霞唐新
Owner 广西大海阳光药业有限公司
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