Resveratrol-cyclodextrin inclusion compound gel and preparation method and application thereof

A technology of cyclodextrin inclusion complex and resveratrol, applied in the field of beauty and skin care, can solve problems such as dryness of the final product, and achieve the effects of diluting fine lines, strengthening hydration, and increasing uniformity

Inactive Publication Date: 2017-11-24
李剑峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Resveratrol is a natural antioxidant that exists in plants. Its anti-oxidation mechanism is mainly to scavenge or inhibit the generation of free radicals, inhibit lipid peroxidation, and regulate the activity of antioxidant-related enzymes. Therefore, using resveratrol Alcohol can be used to prepare facial masks and other beauty and skin care products, but its insoluble characteristics in water determine the limitations of direct application to gel-type masks and eye masks. If it is directly mixed into gel-type masks and eye masks in powder form, the final product will be dry and astringent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 proposes a resveratrol-cyclodextrin inclusion complex gel, comprising the following raw materials in parts by weight: 4 parts of resveratrol, 40 parts of hydroxypropyl-β-cyclodextrin, Zou Bo 1 part of carrageenan carrageenan powder, 1 part of macroalgae extract powder, 1 part of sodium hyaluronate, 60 parts of water, 1 part of butanediol, 1 part of betaine, 1 part of allantoin, polyethylene glycol- 1 part of 40 hydrogenated castor oil, 1 part of polyethylene glycol-60 hydrogenated castor oil, 1 part of titanium dioxide, 1 part of zinc oxide, 1 part of calcium chloride, and 2 parts of essence, 1 part of P. 1 part; wherein, the mass percentage of the resveratrol in the gel is 1.2%.

[0023] The preparation method of the described resveratrol-cyclodextrin inclusion complex gel comprises the following steps:

[0024] (1) First, add the Zoupo carrageenan powder and macroalgae extract powder to 10 parts of the water and stir, then heat it to 95°C and keep the tempe...

Embodiment 2

[0029] Example 2 proposes a resveratrol-cyclodextrin inclusion complex gel, comprising the following raw materials in parts by weight: 0.3 parts of resveratrol, 3 parts of piroxicam-β-cyclodextrin, Zou Bojiao Fork carrageenan powder 5 parts, macroalgae extract powder 5 parts, sodium hyaluronate 6 parts, water 40 parts, butanediol 3 parts, betaine 2 parts, allantoin 2 parts, polyethylene glycol-40 5 parts of hydrogenated castor oil, 5 parts of polyethylene glycol-60 hydrogenated castor oil, 3 parts of titanium dioxide, 3 parts of zinc oxide, 2 parts of calcium chloride and 4 parts of essence, 3 parts of P. 3 parts; wherein, the mass percentage of the resveratrol in the gel is 0.09%.

[0030] The preparation method of the described resveratrol-cyclodextrin inclusion complex gel comprises the following steps:

[0031] (1) First add the Zoubo carrageenan carrageenan powder and macroalgae extract powder to 20 parts of the water and stir, then heat it to 85° C. and keep the tempera...

Embodiment 3

[0036] Example 3 proposes a resveratrol-cyclodextrin inclusion complex gel, comprising the following raw materials by weight: 2 parts of resveratrol, 21 parts of sulfobutyl-β-cyclodextrin, Zou Bo 3 parts of carrageenan carrageenan powder, 3 parts of macroalgae extract powder, 3.5 parts of sodium hyaluronate, 50 parts of water, 2 parts of butanediol, 1.5 parts of betaine, 1.5 parts of allantoin, polyethylene glycol-40 35 parts of hydrogenated castor oil, 3 parts of polyethylene glycol-60 hydrogenated castor oil, 2 parts of titanium dioxide, 2 parts of zinc oxide, 1.5 parts of calcium chloride and 3 parts of essence, 2 parts of E. 2 parts; wherein, the mass percentage of the resveratrol in the gel is 0.65%.

[0037] The preparation method of the described resveratrol-cyclodextrin inclusion complex gel comprises the following steps:

[0038] (1) First, add the Zoupo carrageenan powder and macroalgae extract powder to 15 parts of the water and stir, then heat it to 90°C and keep ...

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PUM

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Abstract

The invention relates to a resveratrol-cyclodextrin inclusion compound gel and a preparation method and application thereof. The gel is prepared from the following raw materials in parts by weight: 0.3-4 parts of resveratrol, 3-40 parts of cyclodextrin, 1-5 parts of chondrus crispus carrageenan powder, 1-5 parts of kelp extract powder, 1-5 parts of sodium hyaluronate and 40-60 parts of water, wherein the resveratrol accounts for 0.09-1.2wt% of the gel. According to the resveratrol-cyclodextrin inclusion compound gel disclosed by the invention, the resveratrol is entrapped in the cyclodextrin, the evenness of the cyclodextrin in the gel is increased, and the skin feeling of a gel type cosmetic product which contains the resveratrol is improved. The resveratrol-cyclodextrin inclusion compound gel disclosed by the invention has a good oxidation resistance effect, has efficacy on smoothening wrinkles, reducing thin wrinkles and accelerating damaged skin to be repaired and also has the functions of strengthening water supplementation, face oxygen radicals can be effectively removed, and the metabolism of cells can be accelerated.

Description

technical field [0001] The invention relates to the technical field of beauty and skin care, in particular to a resveratrol-cyclodextrin inclusion complex gel and a preparation method and application thereof. Background technique [0002] Resveratrol is a polyphenolic compound mainly derived from peanuts, grapes, knotweed, mulberries and other plants. Resveratrol is a natural polyphenol with strong biological properties, also known as stilbene. It is a chemopreventive agent for tumors, and it is also useful for reducing platelet aggregation, preventing and treating atherosclerosis, cardiovascular and cerebrovascular diseases. of chemopreventive agents. Resveratrol is a natural antioxidant existing in plants, and its anti-oxidant mechanism is mainly to scavenge or inhibit the generation of free radicals, inhibit lipid peroxidation, and regulate the activity of antioxidant-related enzymes. Alcohol can be used to prepare facial masks and other beauty and skin care products, b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9711A61K8/9706A61K8/04A61K8/34A61K8/73A61Q19/00A61Q19/08
Inventor 房巍
Owner 李剑峰
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