Externally applied Chinese medicinal composition for relieving eye fatigue

A technology of composition and traditional Chinese medicine, applied in the directions of drug combination, drug delivery, active ingredients of hydroxyl compounds, etc., can solve problems such as intolerance and irritation

Inactive Publication Date: 2017-12-26
陕西新视明医药生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] People often relieve and treat eye fatigue by eye drops, but the way of direct contact with the cornea may cause some people intolerance and ...

Method used

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  • Externally applied Chinese medicinal composition for relieving eye fatigue
  • Externally applied Chinese medicinal composition for relieving eye fatigue
  • Externally applied Chinese medicinal composition for relieving eye fatigue

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 533g wild chrysanthemum, 333g salvia, 400g cork, 30g coptis, 39g pearl powder, 3g menthol, 1.5g borneol;

[0022] Preparation method: the above seven medicines, take wild chrysanthemum, salvia, phellodendri and coptis coptidis, decocted twice with water, filter, concentrate the filtrate to a relative density of 1.05-1.10 (40℃), cool to room temperature, add appropriate amount of ethanol to make the alcohol content reach 50%, refrigerated at 4°C, let stand for 12 hours, filter, and recover the ethanol to obtain the extract extract for use; take pearl powder, add 25% lactic acid, stir well, stir once every half an hour, and hydrolyze at 65°C for 2 times. Filter for 3 hours each time, and the filtrate is a pearl hydrolysate for later use; Beta cyclodextrin for borneol and menthol (borneol, menthol: β-CD=1: 8, β-CD(g): water (ml) =1:10, use a colloid mill to grind for 15min) for inclusion, make beta cyclodextrin inclusion compound, dry for later use; combine the above clear oi...

Embodiment 2

[0025] 510g wild chrysanthemum, 360g salvia, 380g cork, 33g coptis, 37g pearl powder, 3.3g menthol, 1.4g borneol;

[0026] Preparation method: the above seven herbs, take wild chrysanthemum, salvia, phellodendron, and coptis and reflux for 2 to 3 times with 50% ethanol, filter, combine the extracts, and recover the ethanol to obtain the extract extract for use; pearl powder hydrolyzate and inclusion compound The preparation of the substance is the same as in Example 1; the above extract extract is mixed with the pearl hydrolyzate and beta cyclodextrin inclusion compound, and coated on the non-woven fabric to make an eye patch.

Embodiment 3

[0028] 550g wild chrysanthemum, 320g salvia, 430g cork, 28g coptis, 42g pearl powder, 2.5g menthol, 1.6g borneol;

[0029] Preparation method: the above seven medicines, take wild chrysanthemum, salvia, phellodendron, and coptis and ultrasonically extract 2 to 3 times with 70% ethanol, combine the extracts, filter, concentrate the filtrate, centrifuge at 3000r / min for 15min, take the supernatant, and concentrate Prepare the extract for use; the preparation of the pearl powder hydrolyzate and the inclusion compound is the same as in Example 1; the above extract is mixed with the pearl hydrolyzate and beta cyclodextrin inclusion compound, and coated on a non-woven fabric to make Eye patch.

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PUM

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Abstract

The invention relates to an externally applied Chinese medicinal composition for relieving eye fatigue. The composition comprises the following bulk drugs: wild chrysanthemum, Salvia miltiorrhiza, phellodendron, Coptis chinensis, pearl powder, menthol, and borneol. The Chinese medicinal composition provided by the invention has a total improvement rate on eye fatigue up to 91.67%, which is significantly higher than the 33.33% of a placebo group, and has a significant mitigation effect on eye dryness, scorching hot feel, frequent blinking, eye itching, non-sustainable reading, heavy eyes, eye stinging, reflex headache, diplopia, double vision, easy line skip, phengophobia, lacrimation, acid and swollen symptoms.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for external use to relieve eye fatigue, and belongs to the field of traditional Chinese medicine health care. Background technique [0002] Eye fatigue is a common disease in ophthalmology. The dry eyes, astringent eyes, sore eyes, blurred vision and even decreased vision caused by it directly affect people's work and life. Eye fatigue is mainly caused by people looking at the computer or TV screen for a long time, reducing the number of blinks and reducing the secretion of tears. At the same time, the flashing screen strongly stimulates the eyes. It can cause pain in the neck, shoulders, head and other parts of the person. Kind of eye disease. [0003] People often use eye drops to relieve and treat eye fatigue. However, direct contact with the cornea may cause some people intolerance and even irritation due to the irritating ingredients in the eye drops. Massage methods can also relieve ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P27/02A61K35/618A61K31/045
CPCA61K9/0014A61K31/045A61K35/618A61K36/287A61K36/534A61K36/537A61K36/718A61K36/756A61K2300/00
Inventor 张超峰
Owner 陕西新视明医药生物科技有限公司
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