Oral traditional Chinese medicine granule for treating early swelling pain of children traumatic fracture and preparation method

A technology of traditional Chinese medicine granules and trauma, which is applied in the directions of pharmaceutical formulations, non-central analgesics, medical preparations with non-active ingredients, etc.

Inactive Publication Date: 2018-01-16
LUOYANG ORTHOPEDIC TRAUMATOLOGICAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, there are few kinds of medicines specifically for children, so the emergence of oral Chinese medicine granules for orthopedics and traumatology children with definite curative effect, economical safety, and convenient use will be very popular in clinical practice.

Method used

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  • Oral traditional Chinese medicine granule for treating early swelling pain of children traumatic fracture and preparation method
  • Oral traditional Chinese medicine granule for treating early swelling pain of children traumatic fracture and preparation method
  • Oral traditional Chinese medicine granule for treating early swelling pain of children traumatic fracture and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Composition and consumption of the pharmaceutical raw material of granule described in the present invention are as follows by weight percentage:

[0082] Danshen 18, saffron 7, Eupatorium 7, Cyperus 9, Alisma 9, licorice 2, woody fragrance 6, hematoxylin 6, dextrin 16, sucrose powder 18.

[0083] The preparation method of granule of the present invention is as follows:

[0084] 1. Soak Rhizoma Rhizoma Rhizoma Cyperi and half the amount of Danshen in 6 times the amount of 75% ethanol for 48 hours, reflux extraction for 1 hour, filter, and recover ethanol under reduced pressure at 60°C to make a thick extract with a relative density of about 1.1, dry and pulverize for later use;

[0085] 2. Wash Eupatorium, saffron, Alisma, licorice, half the amount of salvia miltiorrhiza, woody incense, and sumac seven herbs with water, add 10 times the amount of water to decoct for 2 hours, filter out the liquid medicine, and add 8 Double the amount of water to cook for 1 hour. Filte...

Embodiment 2

[0088] Composition and consumption of the pharmaceutical raw material of granule described in the present invention are as follows by weight percentage:

[0089] Salvia 20, saffron 8, Eupatorium 8, Cyperus 9, Alisma 8, licorice 3, woody 7, sumac 7, dextrin 16, sucrose powder 14.

[0090] The preparation method of granule of the present invention is as follows:

[0091] 1. Soak Rhizoma Rhizoma Rhizoma Cyperi and half the amount of Danshen in 6 times the amount of 75% ethanol for 48 hours, reflux extraction for 1 hour, filter, and recover ethanol under reduced pressure at 60°C to make a thick extract with a relative density of about 1.1, dry and pulverize for later use;

[0092] 2. Wash Eupatorium, saffron, Alisma, licorice, half the amount of salvia miltiorrhiza, woody incense, and sumac seven herbs with water, add 10 times the amount of water to decoct for 2 hours, filter out the liquid medicine, and add 8 Double the amount of water to cook for 1 hour. Filter out the medicin...

Embodiment 3

[0095] Salvia miltiorrhiza 19, saffron 7, Eupatorium 8, Cyperus 9, Alisma 10, licorice 4, woody 7 parts, sumac 6 parts, dextrin 15, sucrose powder 15.

[0096] The preparation method of granule of the present invention is as follows:

[0097] 1. Soak Rhizoma Rhizoma Rhizoma Cyperi and half the amount of Danshen in 6 times the amount of 75% ethanol for 48 hours, reflux extraction for 1 hour, filter, and recover ethanol under reduced pressure at 60°C to make a thick extract with a relative density of about 1.1, dry and pulverize for later use;

[0098] 2. Wash Eupatorium, saffron, Alisma, licorice, half the amount of salvia miltiorrhiza, woody incense, and sumac seven herbs with water, add 10 times the amount of water to decoct for 2 hours, filter out the liquid medicine, and add 8 Double the amount of water to cook for 1 hour. Filter out the medicinal solution, discard the medicinal residues, combine the two filtrates, and concentrate until the relative density measured at 80°...

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Abstract

The invention discloses an oral traditional Chinese medicine granule for treating early swelling pain of children traumatic fracture and a preparation method. The oral traditional Chinese medicine granule is prepared from the following raw materials in percentage by weight: 15 to 25 parts of radix salviae miltiorrhizae, 1 to 10 parts of saffron crocus, 2 to 10 parts of herba lycopi, 3 to 15 partsof rhizoma cyperi, 2 to 15 parts of rhizoma alismatis, 1 to 4 parts of liquorice root, 2 to 10 parts of radix aucklandiae, 2 to 10 parts of lignum sappan, 10 to 30 parts of powdered sugar, and 10 to 30 parts of dextrin. The preparation method comprises the following steps of a, adding the rhizoma cyperi and half of the radix salviae miltiorrhizae into 6 times of 75% ethyl alcohol, soaking, refluxing and extracting, filtering, and relieving pressure, so as to obtain thick ointment; b, adding water into the herba lycopi, the saffron crocus, the rhizoma alismatis, the liquorice root, half of theradix salviae miltiorrhizae, the radix aucklandiae and the lignum sappan, decocting, filtering to obtain medicine liquor, continuing to add water to decoct, filtering to obtain medicine liquor, removing medicine residues, combining filtrates, and concentrating; c, screening the powdered sugar by a No.5 screen, and drying the dextrin at low temperature; preparing the filtrate, the thick ointment, the powdered sugar and the dextrin into dry particles, and subpackaging, wherein the weight of each bag is 9g. The oral traditional Chinese medicine granule has the functions of resisting inflammation,relieving pain, activating blood circulation and removing blood stasis.

Description

technical field [0001] The invention relates to an oral Chinese medicine granule and its preparation, and mainly provides an oral Chinese medicine granule and a preparation method for treating early swelling and pain of trauma fracture in children. Background technique [0002] Fracture in children is a common frequently-occurring disease in clinic. Swelling and pain are one of the most common clinical symptoms in the early stage of fracture injury in children. Western medicine treatment of post-fracture swelling and pain mainly includes detumescence, anti-exudation drugs, analgesic drugs and other measures, but it often causes severe gastrointestinal reactions and liver disease. Kidney damage. Compared with western medicine, traditional Chinese medicine has the advantages of multiple targets and less side effects, and it has advantages in syndrome differentiation and treatment. Looking at domestic and foreign literature in recent years, it is found that there are many tre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K9/16A61K47/36A61P19/08A61P29/00
Inventor 赵朝锋王昭杜天信张天健
Owner LUOYANG ORTHOPEDIC TRAUMATOLOGICAL HOSPITAL
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