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Pipetting devices for pipetting small liquid volumes

A device, liquid technology, used in the field of pipetting equipment for pipetting small liquid volumes, which can solve problems such as pollution

Active Publication Date: 2021-07-13
HAMILTON BONADUZ AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is a certain risk of contamination from such system fluids, since sometimes it cannot be ruled out that part of the system fluid, ie the liquid-like piston, enters the dosing liquid to be aspirated

Method used

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  • Pipetting devices for pipetting small liquid volumes
  • Pipetting devices for pipetting small liquid volumes
  • Pipetting devices for pipetting small liquid volumes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0105] exist figure 1 a to figure 1 In c, a pipetting device according to the invention is indicated generally at 10 . The pipetting device comprises a pipetting channel 12 which is formed by a cylinder which extends along a channel path K which is formed as a rectilinear channel axis. A piston 14 is accommodated movably along a channel path K in the pipetting channel 12 .

[0106] Piston 14 includes two end caps 16 (for reasons of overview only on figure 1There are reference numerals below in ), between which a plurality of permanent magnets 18 (in this example three permanent magnets 18 ) are housed. In order to achieve a magnetic field with good selectivity along the channel path K, the permanent magnets 18 are polarized along the channel axis K and arranged in pairs with identical poles facing each other. This arrangement results in a magnetic field starting from the piston 14 which is as homogeneous as possible around the channel axis K, i.e. substantially rotationall...

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PUM

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Abstract

A pipetting device (10) for pipetting a metering liquid (32) has a pipetting channel (12) extending along a channel path (K) in which the A piston (14) designed as a solid body is accommodated in order to change the pressure of a working gas (34) wetted on the metering side (14a) facing the metering liquid by movement along the channel path (K) Piston (14). The pipetting device (10) also includes a movement drive (20) for the piston (14), by means of which movement of the piston (14) can be driven along the channel path (K). Likewise, the pipetting device (10) comprises a control device (24) for controlling the movement drive (20). According to the invention it is proposed that the control device (24) is configured to operate the movement drive (20) in order to aspirate a predetermined single metered volume (36) of less than 5 μl, so that the piston (14) moves in the aspiration direction (P), And here its end face (14a) on the metering side sweeps a suction volume that is not less than 1.4 times larger than the single metering volume (36), and the piston (14) then moves along the direction of suction (P) Movement in the opposite anti-aspiration direction (G), and here its metering-side end face (14a) sweeps the anti-aspiration volume, wherein the control device (24) for driving the piston (14) in the aspiration direction (P) ) between the start of the control signal and the end of the control signal for driving the piston (14) in the reverse suction direction (G), elapsed by no more than 50 ms, preferably no more than 30 ms.

Description

technical field [0001] The invention relates to a pipetting device for pipetting metered liquids, wherein pipetting includes drawing and dispensing metered liquids, said pipetting device having a pipetting channel extending along a channel path, in said pipetting channel along The piston, which is formed as a solid body at least in sections, is movably accommodated along the channel path in order to change the pressure of a working gas which wets the piston on the metering side facing the metering liquid by moving along the channel path. , wherein the pipetting device comprises a motion drive for the piston, by means of which the piston can be driven to move along the channel path, wherein the pipetting device has a control device for controlling the motion drive, the control device being configured to use The result is that the motion drive is operated in dispensing mode such that the piston first moves along the channel path in a dispensing direction which increases the pres...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01L3/02
CPCB01L3/0227B01L3/0237B01L2200/14B01L2400/0478G01N35/1065
Inventor 汉斯彼得·罗默弗里多林·吉塞尔
Owner HAMILTON BONADUZ AG