A kind of ginseng polysaccharide preparation and preparation method thereof

A technology of ginseng polysaccharide and preparation, applied in the field of ginseng polysaccharide preparation and preparation thereof, can solve the problems of not using red ginseng polysaccharide components, environmental pollution, cost waste and the like, and achieves improvement of intestinal immunity, cost reduction and low cost Effect

Inactive Publication Date: 2021-05-28
SICHUAN AGRI UNIV
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Shenmai injection has a broad market in my country, but Shenmai injection is extracted by 90% ethanol, and its main components are ginsenoside Rg1, ginsenoside Re, ginsenoside Rb1, ophiopogon saponin D, ophiopogon saponin D′, The 7 ingredients of methyl radix dihydroflavone A and methyl radix dihydroflavone did not utilize the polysaccharide components in red ginseng and radix radix, and the direct discharge of production waste from Shenmai injection not only polluted the environment, It also leads to a direct waste of cost

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of ginseng polysaccharide preparation and preparation method thereof
  • A kind of ginseng polysaccharide preparation and preparation method thereof
  • A kind of ginseng polysaccharide preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0025] The invention discloses a preparation method of ginseng polysaccharide preparation, which comprises the following steps:

[0026] Step 1. Ethanol removal of impurities: Red ginseng and Ophiopogon japonicus were soaked in ethanol with a volume fraction of 70%-90% respectively, and then heated and refluxed for extraction. Red ginseng was extracted 6 times, and Ophiopogon japonicus was extracted twice, each time using 3 times the amount of 70% Reflux extraction with -90% ethanol for 1.5h-2.5h; recover the extraction residue and dry it in a desiccator to prepare red ginseng medicinal residue and Ophiopogon japonicus medicinal residue;

[0027] Step 2. Water extraction and concentration: mix red ginseng medicinal residue and Ophiopogon japonicus medicinal residue at a ratio of 1:1 (w / w), and extract distilled water at a material-to-liquid ratio of 1:20-1:40 at a temperature of 60-100°C Twice, 0.5-1.5h each time, combine the concentrated solution to 1 / 20 of the volume of the ...

Embodiment 1

[0031] A preparation method of Shenmai polysaccharide preparation, comprising the following steps:

[0032] Step 1. Ethanol removal of impurities: soak 100g of red ginseng and 100g of Radix Ophiopogon japonicus in 90% (V / V) ethanol respectively, then heat and reflux for extraction, extract 6 times of red ginseng and 2 times of Radix Ophiopogon japonicus, each time using 3 times the amount of 90% Ethanol reflux extraction for 2 hours; recover the extraction residue and dry it in a desiccator;

[0033] Step 2. Water extraction and concentration: Mix the residues of the two medicinal materials in a ratio of 1:1 (w / w), that is, distilled water is extracted twice at a material-to-liquid ratio of 1:30 at a temperature of 90°C, each time for 1 hour, and the concentrated solution is combined to 1 / 20 of the volume of the original extract, filtered for later use;

[0034] Step 3. Alcohol precipitation: After concentration, add 4 times the amount of absolute ethanol (V / V), let stand ove...

Embodiment 2

[0037] A preparation method of Shenmai polysaccharide preparation, comprising the following steps:

[0038] Step 1. Ethanol removal of impurities: Red ginseng and Ophiopogon japonicus were soaked in ethanol with a volume fraction of 70% respectively, and then heated and refluxed for extraction. Red ginseng was extracted 6 times, and Ophiopogon japonicus was extracted twice, each time with 3 times the amount of 70% ethanol for reflux extraction 2.5 hours; recover the extraction residue, dry in a drier, and prepare red ginseng medicinal residue and Ophiopogon japonicus medicinal residue;

[0039] Step 2. Water extraction and concentration: mix red ginseng medicinal residue and Ophiopogon japonicus medicinal residue at a ratio of 1:1 (w / w), and extract distilled water twice at a material-to-liquid ratio of 1:20 at a temperature of 100°C, each time at 0.5 h, merge the concentrate to 1 / 20 of the volume of the original extract, and filter for subsequent use;

[0040] Step 3. Alcoho...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a ginseng-mai polysaccharide preparation and a preparation method thereof. The preparation method comprises the following steps: respectively adding red ginseng and Radix Ophiopogon japonicus into ethanol for impregnation, then heating and refluxing for extraction, recovering the extraction residue, drying in a desiccator, and preparing Red ginseng medicinal residue and Ophiopogon japonicus medicinal residue; mixing red ginseng medicinal residue and Ophiopogon japonicus medicinal residue, adding distilled water for extraction, and extracting twice; combining the extracts, concentrating and filtering them to prepare a concentrate; Add absolute ethanol to the mixture, let it stand overnight, centrifuge to collect the precipitate, wash it with absolute ethanol and acetone in turn, and then centrifuge; place the precipitate in a freeze-drying equipment, vacuum freeze-dry it, and grind it to obtain Shenmai polysaccharide powder . The preparation process of the polysaccharide preparation is simple, the cost is low, the extraction residue of Shenmai injection is reused, and the polysaccharide preparation has a good immune enhancing effect.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a Shenmai polysaccharide preparation and a preparation method thereof. Background technique [0002] Ginseng is the dry root of Panax genus Araliaceae. It is a perennial herb that likes shade and coolness. It is mainly distributed in Heilongjiang, Jilin, Liaoning and other provinces and deep mountains in the north of Hebei Province. Now it is mostly cultivated artificially. Red ginseng is the dried root and root lotus of ginseng after steaming, and it is a cooked product of ginseng. It is sweet in taste, slightly bitter, and warm in nature. It returns to the spleen, lung, and heart meridian. Red ginseng polysaccharide is one of the important components of red ginseng. Studies have shown that red ginseng polysaccharide has certain free radical scavenging and antioxidant effects in vitro. Modern pharmacological research has found that red ginseng a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): C08B37/00A61K36/8968A61K9/14A61P37/04A61K31/715
CPCA61K9/14A61K31/715A61K36/258A61K36/8968A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 邹元锋陈兴福殷中琼朱忠铠付羽萍贾仁勇李丽霞宋旭
Owner SICHUAN AGRI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap