A polydimethylsiloxane three-dimensional microfluidic channel surface hydrophobic structure forming process

Abstract

The invention provides a polydimethylsiloxane three-dimensional micro-channel surface hydrophobic structure forming process, which is mainly used in micro-droplet manipulation of micro-fluidic chips to solve the problems of fluid adhesion and two-phase fusion on the inner wall of micro-channels. The specific method is: (1) using UV-LIGA technology to make a polydimethylsiloxane microfluidic chip with a microchannel; (2) applying a pulling force on both sides of the chip along the direction of the channel; A metal wire with a diameter smaller than the width of the microchannel is embedded in the flow channel of the polydimethylsiloxane chip in an elastic deformation state; (4) the laser beam penetrates the polydimethylsiloxane material and acts on the surface of the metal wire; (5) Turn off the laser and remove the pulling force in a certain order; compared with the prior art, the nanosecond laser used in the present invention has low cost, high production efficiency, controllable hydrophobic area size and hydrophobic position, and the hydrophobic structure is a regular wavy wrinkle structure. The structure size can be tuned at the micro-nano scale.

Description

technical field [0001] The invention relates to the field of microfluidic chip production, in particular to a polydimethylsiloxane three-dimensional microfluidic channel surface hydrophobic structure forming process. Background technique [0002] The microfluidic chip is a miniaturized and integrated portable analysis device. The size of the flow channel is in the order of microns, and the analysis dose is measured in microliters. In some respects, the microfluidic channels in microfluidic chips need to undergo surface hydrophobic or hydrophilic modification to meet the actual application requirements. For example, in the application of micro-droplet manipulation, the superhydrophobic modification of the inner surface of the pipeline can greatly reduce the transport resistance of the flow channel, change the transport direction of the micro-droplet sample to be operated at will, and even cross one platform to another The platform performs three-dimensional operations. This...

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Problems solved by technology

However, the cost of the femtosecond laser required by this method is extremely high, and the surface of the prepared superhydrophobic structure is very rough, and the processing efficiency is low.

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