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Pharmaceutical composition for treating superficial dermatomycosis

A fungal skin disease and drug technology, applied in the field of medicine, can solve problems such as the influence of body organs, toxic and side effects, and limited effects, and achieve the effects of strong sterilization effect, good antibacterial effect, and improved fungicidal effect.

Inactive Publication Date: 2018-08-28
湖南三五二环保科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Anti-deep fungal infection drugs include flucytosine, amphotericin B, nystatin, erythromycin, mepamycin (mepatroxine, clotrimazine), fluconazole (diflucan, manifene) , Yilikang), itraconazole (Spiranox), etc., if anti-deep drugs such as flucytosine are directly applied to the affected area of ​​fungal skin diseases, the effect is very limited, such as injection of anti-deep drugs such as flucytosine, Toxic and side effects, causing bad effects on body organs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1, a kind of medicine for the treatment of fungal skin disease, its weight ratio is: Soaking agent: 3 parts of sulfur, 1 part of potassium permanganate, 1 part of acetic acid, 5 parts of ginger, 5 parts of garlic, 3 parts of table salt; Ointment: 2 parts of chitosan nano-microcapsules loaded with 5-fluorouracil, 9 parts of petrolatum.

Embodiment 2

[0035] Embodiment 2, a kind of medicine for the treatment of fungal skin disease, its weight ratio is; Soaking agent: 1 part of sulfur, 0.5 part of potassium permanganate, 1 part of acetic acid, 3 parts of ginger, 3 parts of garlic, 2 parts of table salt; Ointment: 1 part of chitosan nano-microcapsules loaded with 5-fluorouracil, 9 parts of petrolatum.

Embodiment 3

[0036]Embodiment 3, a kind of medicine for the treatment of fungal skin disease, its weight ratio is: soaking agent: 1 part of sulfur, 1 part of potassium permanganate, 1 part of acetic acid, 5 parts of ginger, 3 parts of garlic, 2 parts of table salt; Cream: 2 parts of chitosan nano-capsules loaded with 5-fluorouracil, 11 parts of petrolatum.

[0037] Typical case 1: Wu, 43 years old, female, obese, suffering from jock itch. At the beginning, she felt itchy, and then she often scratched with her hands, and then found erythema, the skin of the affected area was damaged, with clear edges and raised erythema, which gradually expanded , there is shedding on it, which gradually turns from red to brown, and it is often scratched with hands. As a result, the center of the lesion gradually heals automatically, develops to the surrounding, and causes multiple places. The edge inflammation of the erythema is more obvious, and there may be rashes, blisters, and scabs on it. The skin, ev...

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Abstract

The invention relates to a pharmaceutical composition for treating superficial dermatomycosis. The pharmaceutical composition comprises a soaking agent and paste. The soaking agent is prepared from, in parts by weight, 1-3 parts of sulfur, 0.5-1 part of potassium permanganate, 1-2 parts of acetic acid, 3-5 parts of ginger, 3-5 parts of garlic and 1-3 parts of salt. The paste is prepared from, in parts by weight, 1-2 parts of chitosan nano-microcapsules with 5-fluorouracil and 9-11 parts of vaseline. The pharmaceutical composition has the advantages that every 100g of the soaking agent is blended with 1L of warm water with the temperature of 35-45 DEG C, a clean towel is soaked in the soaking agent and put on wounds for hot compress, horny layers of the wound skin are softened, and sterilization and disinfection are realized; the ginger can promote angiectasis to enable pores of bodies to expand, and the garlic is a natural botany broad spectrum antibiotic; after hot compress, the prepared paste is applied to the wounds; the 5-fluorouracil of the nano-drug in the paste can enter tissues of the wounds easily in a local environment, so that fungi are killed deeply, and side effects and proneness to relapse are avoided.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular to medicines for treating superficial fungal skin diseases. Background technique [0002] Fungal infection can be divided into two types: superficial fungal infection and deep fungal infection. Superficial infection is caused by ringworm invading the skin, hair, nails and other body parts. Symptoms: the damage is mostly limited to one side, and the number of small blisters varies at the beginning. After the blister fluid dries up, the scale gradually expands. Over time, the skin at the desquamation area is rough and thickened, the skin lines are wide and deep, and it loses its normal luster and flexibility. Sex, touch with a sense of coarse sand. The fungus only invades the surface, cuticles, hair and deck. Fungal dermatosis refers to hand, foot, onychomycosis. The superficial fungal infection between the fingers (toes) and the skin of the palm and plantar is called tinea manuum...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K31/513A61K9/06A61K47/06A61K47/36A61P17/00A61P31/10A61K31/19A61K33/04A61K33/14A61K33/32
CPCA61K9/0004A61K9/0014A61K9/06A61K31/19A61K31/513A61K33/04A61K33/14A61K33/32A61K36/8962A61K36/9068A61K47/06A61K47/36A61K2300/00
Inventor 谢耀明
Owner 湖南三五二环保科技有限公司
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