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Fujie bacteriostatic spray as well as preparation method and application thereof

A spray and gynecological technology, applied in local antibacterial agents, pharmaceutical formulations, aerosol delivery, etc., can solve problems such as tissue hyperplasia, vaginal skin and mucous membrane damage, prevent reinfection, repair mucous membranes, and be easy to operate Effect

Inactive Publication Date: 2018-10-19
博凯药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] One of the objectives of the present invention is to provide an antibacterial spray for women's cleansing, to improve the existing gynecological antibacterial drugs mostly made of acidic disinfectants, long-term use will cause damage to vaginal skin and mucous membranes, and even cause tissue proliferating technical problems

Method used

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  • Fujie bacteriostatic spray as well as preparation method and application thereof
  • Fujie bacteriostatic spray as well as preparation method and application thereof
  • Fujie bacteriostatic spray as well as preparation method and application thereof

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preparation example Construction

[0072] According to the second aspect of the present invention, the present invention provides a preparation method of Fujie antibacterial spray, comprising the steps of: extracting Chinese medicine extract, fucoidan oligosaccharide, borneol, chlorhexidine acetate, optional auxiliary materials and The water is evenly mixed to prepare the Fujie Antibacterial Spray.

[0073] The preparation method of the Fujie bacteriostatic spray provided by the invention has simple process and convenient operation, can be applied to large-scale industrial production, and can improve production efficiency.

[0074] In a preferred embodiment of the present invention, the preparation method of the Chinese medicine extract comprises the steps of: extracting Centella asiatica, Cnidium chinensis, Phellodendron Phellodendron, Sophora flavescens, Scutellaria baicalensis, rhubarb and neem bark with water, filtering to take the filtrate, concentrating , dried to obtain the Chinese medicine extract.

[...

Embodiment 1

[0080] This embodiment provides a Fujie antibacterial spray, each 100g spray includes 0.2g of Chinese medicine extract, 1g of fucoidan oligosaccharide, 0.5g of borneol, 0.3g of chlorhexidine acetate, 5g of lauryl hydroxysulfobetaine, Disodium laureth sulfosuccinate 5g, sodium cocoamphoacetate 5g, Tween 80 2g and sodium benzoate 0.25g, the balance is water, wherein the traditional Chinese medicine extract is calculated in parts by mass as follows Prepared by extracting raw materials: 15 parts of Centella asiatica, 10 parts of Cnidium chinensis, 20 parts of Cortex Phellodendri, 10 parts of Sophora flavescens, 20 parts of Scutellaria baicalensis, 10 parts of rhubarb and 15 parts of neem bark.

Embodiment 2

[0082] This embodiment provides a Fujie antibacterial spray, each 100g spray includes 1g of Chinese medicine extract, 0.2g of fucoidan oligosaccharide, 0.5g of borneol, 0.05g of chlorhexidine acetate, 5g of lauryl hydroxysulfobetaine, Disodium laureth sulfosuccinate 5g, sodium cocoamphoacetate 5g, Tween 80 2g and sodium benzoate 0.25g, the balance is water, wherein the traditional Chinese medicine extract is calculated in parts by mass as follows Prepared by extracting raw materials: 15 parts of Centella asiatica, 20 parts of Fructus Cnidii, 10 parts of Cortex Phellodendri, 20 parts of Sophora flavescens, 10 parts of Scutellaria baicalensis, 15 parts of rhubarb and 10 parts of neem bark.

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Abstract

The invention provides a Fujie bacteriostatic spray as well as a preparation method and application thereof and relates to the technical field of gynecological drugs. In the Fujie bacteriostatic spray, the spray per 100g is prepared from 0.2-1g of traditional Chinese medicine extract, 0.2-1g of brown algae oligosaccharides, 0.5-2g of borneol, 0.05-0.3g of chlorhexidine acetate and the balance of water. The traditional Chinese medicine extract is mainly extracted from asiatic pennywort herb, fructus cnidii, cortex phellodendri, radix sophorae flavescentis, radix scutellariae, radix et rhizoma rhei and cortex meliae, and the technical problem that most of the existing gynecological bacteriostatic drugs are prepared with acid disinfectants, can cause damages on vagina skin and mucosa after being used for a long time and even causes tissue proliferation. The Fujie bacteriostatic spray provided by the invention can effectively inhibit growth and propagation of staphylococcus aureus, candidaalbicans and escherichia coli, can repair the mucosa, prevents reinfection with microorganisms, can maintain normal flora and acid-base balance of a vagina at the same time and promotes female reproductive health.

Description

technical field [0001] The invention relates to the technical field of gynecological medicines, in particular to a fujie antibacterial spray and its preparation method and application. Background technique [0002] Due to the particularity of female reproductive organs, gynecological inflammation has become a common and frequently-occurring disease in adult women. Its clinical manifestations are diverse, the etiology is complex, and it is often accompanied by a variety of serious complications, which have a great impact on women's life and work. [0003] At present, there are many kinds of antibacterial drugs used in gynecology, but most of the antibacterial drugs are products made of acidic disinfectants with a certain concentration requirement. Long-term use of such drugs will cause damage to vaginal skin and mucous membranes, and even cause tissue hyperplasia. [0004] In view of this, the present invention is proposed. Contents of the invention [0005] One of the obj...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/12A61P15/00A61P31/02A61P15/02A61K31/045A61K31/702A61K31/155
CPCA61K9/0014A61K9/0034A61K9/12A61K31/045A61K31/155A61K31/702A61K36/23A61K36/234A61K36/489A61K36/539A61K36/58A61K36/708A61K36/756A61P15/00A61P15/02A61P31/02A61K2300/00Y02A50/30
Inventor 刘洪生胡晓娟张荣培李跃克
Owner 博凯药业有限公司
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