A rectification tower for reflux improved 2-cyanopyrazine

Abstract

The invention relates to a refluxing improved rectifying tower for 2-cyanopyrazine. The refluxing improved rectifying tower comprises a tower body provided with an extraction hole, a plurality of pieces of tower plates and a refluxing system, wherein the refluxing system comprises an extraction pipe connected with the extraction hole, a heat exchanger connected with the extraction pipe and a refluxing main pipe connected with the heat exchanger; each tower plate comprises a hollow shell body, a plurality of sieve holes which are formed in the shell body and penetrate through the shell body, and a plurality of spraying holes which are formed in a non-sieve-hole region of the bottom surface of the shell body; a refluxing auxiliary pipe, which is communicated with the inner part of the shellbody and extends out of the tower body, is arranged on a side face of each tower plate; each refluxing auxiliary pipe is communicated with the refluxing main pipe and an auxiliary pipe valve is arranged on a pipe body; each sieve hole is internally provided with a sealing circular ring which is coaxial with the sieve hole and is fixedly connected with the shell body; a main pipe valve is arrangedat the tail end of the refluxing main pipe. According to the refluxing improved rectifying tower for the 2-cyanopyrazine, the characteristic that positions of the different tower plates correspond todifferent separation efficiency can be sufficiently utilized, so that the purification effect of single-time refluxing is remarkably improved and the refluxing time needed for reaching the effect is effectively shortened, and furthermore, the whole efficiency of refluxing operation is greatly improved.

Description

technical field

[0001] The invention relates to the field of rectification equipment, in particular to a rectification tower for 2-cyanopyrazine with improved reflux. Background technique

[0002] 2-cyanopyrazine is an important chemical raw material and intermediate, which has a wide range of uses in the fields of spices and medicine. Especially in medicine, 2-cyanopyrazine can prepare anti-tuberculosis drug pyrazinamide. Among them, regarding its preparation method, Tianjin University discloses that propylene glycol and ethylenediamine are used as raw materials to obtain 2-cyanopyrazine through two reactions; Shanghai Petrochemical Research Institute discloses that 2-methylpyrazine is used as raw material, and ammonia Synthesis of 2-cyanopyrazine by oxidation technique; etc. In the preparation process of 2-cyanopyrazine, in addition to the reaction control steps, the distillation purification process is also closely related to the product purity and yield.

[0003] As a...

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