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Method for extracting noni general flavones

An extraction method and technology of total flavonoids are applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., to achieve the effects of reducing production costs, being environmentally friendly, and being simple to operate.

Inactive Publication Date: 2018-11-16
杭州耕香跨境电子商务有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The mechanical force-assisted extraction technology is expected to completely replace the traditional extraction technology, but there is no report on the extraction of noni total flavonoids using this technology

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Put 1g of dry Noni medicinal material with a moisture content of 10% into a ball mill together with 0.5g of sodium carbonate, and ball mill for 25min; take out the ball mill powder, add 10mL of ethanol-water (40%) solution, and ultrasonically extract 3 times at 50°C for 40min. The extract was collected, and an appropriate amount of the extract was taken to determine the total flavonoid content according to the aluminum nitrate color method, and the extraction rate was 26.05 mg / g.

Embodiment 2

[0031] Put 1g of dry Noni medicinal material with a moisture content of 10% into a ball mill together with 0.5g of sodium carbonate, and ball mill for 25min; take out the ball mill powder, add 10mL of ethanol-water (40%) solution, and ultrasonically extract 3 times at 50°C for 50min. The extract was collected, and an appropriate amount of the extract was taken to determine the total flavonoid content according to the aluminum nitrate color method, and the extraction rate was 28.74 mg / g.

Embodiment 3

[0033] Put 1g of dried Noni medicinal material with a moisture content of 10% into a ball mill together with 0.4g of sodium hydroxide, and ball mill for 30min; take out the ball mill powder, add 10mL of ethanol-water (40%) solution, ultrasonicate at 50°C for 50min, and extract 3 times , collect the extract, take an appropriate amount of the extract to measure the total flavonoid content according to the aluminum nitrate color method, and the extraction rate is 30.21mg / g.

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PUM

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Abstract

The invention discloses a method for extracting noni general flavones. The noni general flavones are extracted from noni by adopting mechanochemistry and ultrasonic-assisted extraction technologies. The basic principle is that the cell walls of noni are broken under the action of high-energy mechanical force, flavones and other active materials are released out, polysaccharides and other impurities and solid-phase reagents form specific complexes so as to be removed, and by adopting the ultrasonic-assisted extraction, the extraction rate of the noni general flavones is improved.

Description

technical field [0001] The invention relates to the technical field of extraction of natural medicines, in particular to a method for extracting noni total flavonoids. Background technique [0002] Noni is Morinda citrifolia L., a plant of the genus Morinda of Rubiaceae, also known as Morinda citrifolia L. A perennial evergreen broad-leaved shrub or small tree growing in tropical and subtropical regions. In foreign countries, it is also known as Indian mulberry, mengkudu, pain relief tree, cheese fruit, etc. The roots, stems, leaves, skins, flowers and fruits of Noni all have medicinal value. Polynesian aborigines have used it as folk medicine for more than 2,000 years. Modern pharmacological studies have shown that Noni has antioxidant, antibacterial, and antitumor properties. , anti-diabetes, anti-inflammatory analgesic, liver protection, cardiovascular protection, immune regulation and other effects. As more and more medicinal value and health care functions are confir...

Claims

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Application Information

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IPC IPC(8): A61K36/746
CPCA61K36/746A61K2236/15A61K2236/333A61K2236/39A61K2236/51A61K2236/53
Inventor 王平陆雨
Owner 杭州耕香跨境电子商务有限公司
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