Wormwood plaster and preparation method thereof

A technology of wormwood ointment and mugwort leaves, which is applied in ointment delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problems of rough surface, scar canceration, and hard texture, so as to improve compatibility and prevent scars Generates and enhances the effect of stability and stress resistance

Active Publication Date: 2018-11-27
GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It will appear itching, tingling and grow continuously, the thickness can reach several millimeters or several centimeters, the surface is rough, the texture is hard, inelastic, and ulceration can also occur due to friction, pulling or grasping. Timely treatment can lead to scar cancer and other hazards. Currently, there is no definite treatment drug

Method used

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  • Wormwood plaster and preparation method thereof
  • Wormwood plaster and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1, the preparation of Folium Artemisiae Argyi essential oil

[0040] a Get 2kg of Artemisia argyi leaves of natural drying, pulverize, pass 80 orders, get coarse powder;

[0041] b Put the coarse powder obtained in step a into a supercritical extraction device, adjust the temperature of the extraction device to 50 ° C, and feed CO 2 , adjust the pressure inside the extractor to 25MPa, adjust the CO 2 The flow rate of the method is 20kg / h, and the extraction time is 80min, to obtain the thick substance of Folium Artemisiae Argyi;

[0042] c. Add the crude Artemisia argyi leaf material obtained in step b into a molecular distillation device, and pour liquid nitrogen into the cold well. The conditions of the molecular distillation device are set as follows: the jacket temperature is set to 70°C, and the feed rate is 130ml / h , the temperature of the evaporation layer is 80°C, the temperature of the condensation layer is 45°C, and the pressure is less than 0.1Pa, ...

Embodiment 2

[0043] Embodiment 2, the preparation of Folium Artemisiae Argyi extract

[0044] A get 2kg of naturally dried Artemisia argyi, pulverize, pass 80 orders, get coarse powder;

[0045] B put the coarse powder obtained in step A into a supercritical extraction device, adjust the temperature of the extraction device to 40°C, and feed CO 2 , adjust the pressure inside the extractor to 16MPa, adjust the CO 2 The flow rate of the method is 20kg / h, and the extraction time is 80min, to obtain the thick substance of Folium Artemisiae Argyi;

[0046] C. Put the crude Artemisia argyi leaf material obtained in step B into the molecular distillation device, and pour liquid nitrogen into the cold well. The conditions of the molecular distillation device are set as follows: set the jacket temperature to 80°C, and the feed rate to 130ml / h , the temperature of the evaporation layer is 120°C, the temperature of the condensation layer is 60°C, and the pressure is less than 0.1Pa, then pour the t...

Embodiment 3

[0047] Embodiment 3, a kind of wormwood ointment

[0048] Described wormwood ointment is made up of following components and parts by weight thereof:

[0049] 0.5 part of Folium Artemisiae essential oil, 5 parts of Folium Artemisiae extract, 0.2 part of paeonol, 0.4 part of batyl alcohol, 2 parts of menthol and 70 parts of petrolatum; Thing is the Folium Artemisiae Argyi extract that embodiment 2 makes.

[0050] Preparation

[0051] S1 Mix vaseline and batyl alcohol, heat in a water bath to 75°C, stir until completely dissolved, and cool to 65°C to obtain a mixture I;

[0052] S2 Add Artemisia argyi extract, paeonol and menthol to the mixed solution I obtained in step S1 at a temperature of 65° C., stir until completely dissolved, and cool to 55° C. to obtain mixed solution II;

[0053] S3 Add Artemisia argyi essential oil to the mixed liquid II obtained in step S2 at a temperature of 55°C, stir evenly, fill while it is hot, and cool to obtain.

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Abstract

The invention belongs to the technical field of Chinese medicine preparations, in particular to a wormwood plaster and a preparation process thereof. The wormwood plaster mainly comprises folium artemisiae argyi essential oil, folium artemisiae argyi extract, paeonol, shark liver alcohol, mentholum and vaseline. The wormwood plaster has the advantages of sterilizing, diminishing inflammation, preventing skin from being invaded by bacteria, relieving skin pruritus and skin inflammation, and repairing damaged skin. Meanwhile, the wormwood plaster also has the effect of preventing melanin production, promoting normal repair of skin soft tissue, and preventing skin tissue fibrosis reaction, thereby preventing the occurrence of scars, the plaster especially has significant therapeutic effect onpathological scars. The plaster is an ideal pharmaceutical preparation with the functions of sterilization, diminishing inflammation and scar removal.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a wormwood ointment and a preparation method thereof. Background technique [0002] Artemisia argyi is a perennial herbal medicinal plant belonging to the Compositae plant Artemisia argyi Levl.etVant. It is resistant to cold and drought, has a strong ability to adapt to soil climate, and grows vigorously in fertile and moist soil. It is generally 45-120cm high, the stem is erect, cylindrical and has obvious ribs, and most of the base is lignified. Artemisia argyi is the dried leaf of wormwood. Traditional Chinese medicine classifies it as a medicinal material for dispelling cold. Zhang Zhongjing's "Synopsis of the Golden Chamber" and "Treatise on Febrile Diseases" respectively included Baiye Decoction and Jiaoai Decoction, which use moxa as medicine. is still widely used. [0003] With the development of society, especially the incr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/282A61K9/06A61P17/02A61P17/00A61P17/04A61K31/12A61K31/045
CPCA61K9/0014A61K9/06A61K31/045A61K31/12A61K36/282A61K47/06A61K2236/37A61P17/00A61P17/02A61P17/04A61K2300/00
Inventor 王一飞马婧曹薇
Owner GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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