Preparation method of skincare chloasma dispeling capsule
A technology for capsules and freckle removal, which is applied in the field of preparation of beauty-preserving and freckle-removing capsules, can solve the problems of less obvious curative effect, increased irritation, slow onset of retinoic acid, etc., and achieves the effects of shortening the onset time and improving the effective treatment efficiency.
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Embodiment 1
[0045] Weigh each component according to the following formula:
[0046]
[0047] Prepare as follows:
[0048] 1) Rhodiola, Radix Polygoni Multiflori and Angelica were reflux extracted three times with 70% ethanol aqueous solution (volume), the first time was extracted with ethanol with 6 times the volume of the medicinal material for 3 hours, and the second time with ethanol with 4 times the volume of the medicinal material for 2 hours , for the third time, extract with ethanol that is 4 times the volume of the medicinal material for 1 hour, combine the extracts, filter, recover the ethanol, and use the obtained solution for later use;
[0049] 2) Process safflower and Rhododendron by steam distillation, take 80g of dried safflower and 200g of Rhododendron, pulverize them with a common pulverizer and pass through a 50-mesh sieve, then mix them evenly, and extract 5 by boiling with 6 times the volume of water hours, using n-hexane to extract the water extract to obtain an ...
Embodiment 2
[0064] Embodiment 2, the capsules prepared respectively in Example 1 and Comparative Example 1 are used clinically, and its curative effect on the original disease is compared
[0065] In order to compare the curative effect of Jingzhu Jingtian Quban Capsule prepared by the present invention and Jingzhu Today Quban Capsule prepared by the original method, Beijing Jingzhu Traditional Chinese Medicine Hospital included 120 patients with chloasma, and were randomly divided into A group and B group, each 60 cases. Wherein Group A was treated with Jingzhu Jingtian Quban Capsule prepared by the present invention (Example 1), and Group B was treated with Jingzhu Jingtian Quban Capsule prepared by the original method (Comparative Example 1). Both groups were given 2 times a day, 4 capsules each time, 3 months as a course of treatment.
[0066] The curative effect judging standard is: the integral is calculated by the sum of the skin lesion area and the skin color score. Lesion area ...
Embodiment 3
[0074] Embodiment 3, using the capsules prepared respectively in Example 1 and Comparative Example 1 for clinical use, and comparing their curative effects against new indications
[0075] Beijing Jingzhu Hospital of Traditional Chinese Medicine used the Jingzhu Jingtian Quban Capsule prepared by the present invention in the process of treating chloasma, and found that the medicine also had a curative effect on female patients with primary dysmenorrhea of Qi stagnation and blood stasis type. Preliminary observations were made. Sixty cases of primary dysmenorrhea patients of Qi stagnation and blood stasis type were randomly divided into treatment group and control group, 30 cases in each group. The treatment group was treated with Jingzhu Jingtian Quban Capsules prepared by the present invention, and the control group was treated with Jingzhu Jingtian Quban Capsules prepared by the original method. They were treated for 3 months, and the curative effect and visual analogue sc...
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