Vitamin D inclusion powder, preparation method thereof and application of inclusion powder to healthcare food tablet

Abstract

The invention relates to a vitamin D inclusion powder, a preparation method thereof and an application of the inclusion powder to a healthcare food tablet, and belongs to the technical field of medical health care. The particle diameter range of the vitamin D inclusion powder is smaller than or equal to 380 micrometers, and the vitamin D inclusion powder comprises vitamin D, antioxidants and pharmaceutically acceptable solvents, fillers and flow aids. According to the method, active components are pretreated, the solvents are dispersed and added into auxiliary materials to perform granulation,mixing uniformity of the active components is ensured, and the stability of the vitamin D is ensured. In addition, the vitamin D inclusion powder can be used for preparing the healthcare food tablet,the prepared oral tablet is good in content uniformity, the vitamin D is good in stability, production and running cost is reduced, and production benefits are improved. Moreover, types of the used auxiliary materials are conventional auxiliary materials, so that unpredictable side effects caused by various auxiliary materials can be avoided.

Description

technical field [0001] The invention belongs to the technical field of medicine and health care, and in particular relates to a vitamin D inclusion powder, a preparation method thereof and an application in health food tablets. Background technique [0002] Vitamins are micronutrients needed by organisms, but generally cannot be produced by organisms themselves, and must be obtained through diet and other means. Vitamins cannot produce energy and form cells like carbohydrates, proteins and fats, but they regulate the metabolism of organisms. [0003] Vitamin D can be called the rickets vitamin and is an essential fat-soluble vitamin for the human body. Rickets is a nutritional metabolic syndrome that occurs during human evolution and development. Basic and clinical studies have shown that rickets is not only a metabolic disease caused by nutritional deficiency, but also a bio-social disease. Vitamin D deficiency rickets is a chronic systemic nutritional disease caused by ...

AI Technical Summary

Problems solved by technology

The capsule shell material does not contain active ingredients, has high impurity content, and has relatively many side effects

Although the preparation process of tablets is complicated, the storage conditions are not high, so they are suitable for long-term storage.

Vitamin D is a trace element, which usually accounts for about 0.002% of the tablet. In the preparation of low-dose vitamin D, there are many disadvantages that it cannot be mixed evenly, and the stability of vitamin D is not good. Pure powder is directly mixed with other excipients. Mixing is easy to degrade, and the inclusion powder of vitamin D on the market is not very uniform due to particle size.

The traditional mixing method is to use equal increments or prolong the mixing time to improve the mixing uniformity, the process is complex and time-consuming

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