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Non-irritating, non-blurring, photostable ophthalmic sunscreen composition

An ophthalmic, inorganic technology, applied in the direction of drug combination, inorganic active ingredients, active ingredients of heterocyclic compounds, etc., can solve problems such as ineffectiveness

Inactive Publication Date: 2019-05-24
A EBBIE SOROUDI MD MS CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This would further render the formulation less effective for its proposed use

Method used

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Examples

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Effect test

Embodiment 1

[0052] An ophthalmic sunscreen solution can be synthesized by mixing 5% micronized zinc oxide and 3% ocinoate in an ophthalmic artificial tear formulation. The solution may contain 0.1% sodium carboxymethylcellulose; 0.25% glycerin; boric acid; calcium chloride dihydrate; erythritol; levocarnitine; magnesium chloride hexahydrate; potassium chloride; purified water; sodium borate decahydrate and sodium citrate dihydrate.

Embodiment 2

[0054] An ophthalmic sunscreen solution can be synthesized by mixing a series of 5% micronized titanium dioxide and 3% octilisate in ophthalmic artificial tears.

Embodiment 3

[0056] Can be obtained by mixing a series of 5% micronized zinc oxide and 3% osinolate in an ophthalmic ointment consisting of hypromellose, boric acid, sodium perborate, phosphonic acid, potassium chloride, purified water, and sodium chloride Zhonglai Synthetic Sunscreen Ointment for Eyes.

[0057] This disclosure describes the use of (preferably Tinosorb M, IUPAC name 2,2'-methanediylbis[6-(2H-benzotriazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl) Phenol]) as its active ingredient ophthalmic sunscreen compositions. is a trade name for a range of UV absorbers, including the following: Betrazino ( S); Bisotrozole ( M); Three-biphenyltriazine ( A2B); and octyl methoxycinnamate ( OMC). M is a photostable sunscreen composition with multiple chemical properties superior to all other sunscreens currently available, making it an ideal candidate for sunscreen formulations specifically designed for direct application to the ocular surface.

[0058] Bisotrozole (provided by BA...

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Abstract

A non-irritation, non-blurring, photostable ophthalmic sunscreen composition contains at least one of the following: bemotrizinol; bisoctrizole; tris-biphenyl triazine; and / or octyl methoxycinnamate.A liquid vehicle base is then a remainder of the solution by weight. The composition is an artificial tear formulation or an ophthalmic suspension or ointment. The composition may include at least oneinorganic and / or at least one organic active ingredient. The inorganic active ingredients may include, but not be limited to zinc oxide, titanium dioxide, iron oxide, zirconium oxide, and cerium oxide. The organic active ingredients may include, but not be limited to dioxybenzone, octinoxate, octisalate, homosalate, avobenzone, octocrylene, para-aminobenzoic acid, cinoxate, methyl anthranilate, octocrylene, padimate O, ensulizole, sulisobenzone, trolamine salicylate, and ecamsule.

Description

[0001] Cross References to Related Applications [0002] This international patent application claims priority to U.S. Patent Application No. 15 / 648,107, filed July 12, 2017, and U.S. Provisional Patent Application No. 62 / 361,189, filed July 12, 2016. The entire contents of all priority applications (non-provisional and provisional) are hereby incorporated by reference in their entirety. [0003] manual: field of invention [0004] The present invention relates generally to a sunscreen formulation designed to protect the eye, including the conjunctiva, cornea, lens and retina. More specifically, the present invention relates to a non-irritating sunscreen that is applied directly to the ocular surface of the eye to provide protection from ultraviolet radiation. Background of the invention [0005] Ultraviolet radiation is part of the electromagnetic spectrum that reaches Earth from the sun. It has shorter wavelengths than visible light and is invisible to the naked eye. T...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P17/00A61K8/00
CPCA61Q17/04A61K8/496A61P17/18A61P43/00A61P27/02A61K31/216A61K31/4192A61K31/53A61K33/30A61K9/51A61K9/0048A61K2300/00
Inventor A·埃比·索劳迪
Owner A EBBIE SOROUDI MD MS CORP
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