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A kind of whitening skin care composition and preparation method thereof

A skin care composition and the technology of the composition are applied in the directions of skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve problems such as poor stability of arbutin, achieve rosy skin, brighten skin tone, and reduce melanin production amount of effect

Active Publication Date: 2021-09-03
CHENGDU UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example: arbutin has poor stability, kojic acid, nicotinamide, etc. have certain skin irritation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A skin care composition with whitening effect, which comprises: glucoraphanin, nonapeptide-1, palmitoyl tripeptide-5, trehalose and cactus extract, wherein, 5-10 parts of glucoraphanin, 5-10 parts Nonapeptide-1, 5-10 parts of palmitoyl tripeptide-5 and 85 parts of trehalose are made into solid-phase freeze-dried powder, which is dissolved in liquid-phase cactus extract before use. The mass volume fraction of cactus extract is 15 % (that is, 1.5 kilograms of cactus is made into 10000mL extract), its specific preparation method is as follows:

[0023] (1) According to the prescription, 500mg glucoraphanin, 500mg nonapeptide-1, 500mg palmitoyl tripeptide-5, and 8500mg trehalose were fully dissolved in 1000mL distilled water, sterilized by membrane filtration with a pore size of 0.22μm, and then averaged Packed in 1000 sterilized penicillin bottles, vacuum freeze-dried into powder, and then sealed and preserved;

[0024] (2) According to the recipe, crush 1.5 kg of cactus,...

Embodiment 2

[0027] A skin care composition with whitening effect, which comprises: glucoraphanin, nonapeptide-1, palmitoyl tripeptide-5, trehalose and cactus extract, wherein, 8 parts of glucoraphanin, 8 parts of nonapeptide-1 , 8 parts of palmitoyl tripeptide-5, 76 parts of trehalose are made into solid-phase lyophilized powder, which are dissolved and used in liquid-phase cactus extract before use, and the mass volume fraction of the cactus extract is 20% (that is, 2 kilograms of cactus Make 10000mL extract).

[0028] The preparation method of the above-mentioned skin care composition with whitening effect, the specific steps are as follows:

[0029] (1) According to the prescription, 800mg glucoraphanin, 800mg nonapeptide-1, 800mg palmitoyl tripeptide-5, 7600mg trehalose were fully dissolved in 1000mL distilled water, and sterilized by membrane filtration with a pore size of 0.22 μm, and then averaged Packed in 1000 penicillin bottles, vacuum freeze-dried into powder, and then sealed ...

experiment example 1

[0040] The whitening skin care product prepared in Example 1 of the present invention was tested on human skin, specifically as follows:

[0041] Select 20 male college students and 20 female college students. The skin of 1 square centimeter of the back neck is used as the experimental site, and the other parts are the control area. The composition of the present invention is applied to the experimental site 3 times every morning, noon and evening, and cannot be applied to the experimental site. Apply any cosmetics continuously for 10, 15, 20, 25 and 30 days, observe the whitening effect of the application site and the control area of ​​the back of the neck without application samples, and measure the change of melanin content in the skin.

[0042] Comparing the smeared area with the control area, it is found that the longer the smearing time, the greater the difference in skin color, the smeared area is obviously whiter than the control area, and the longer the time, the melan...

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PUM

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Abstract

The invention discloses a whitening skin care composition and a preparation method thereof. The composition comprises: glucoraphanin, nonapeptide-1, palmitoyl tripeptide-5, trehalose and cactus extract; wherein, the glucoraphanin , nonapeptide-1, palmitoyl tripeptide-5, and the weight ratio of trehalose are (5~10): (5~10): (5~10): (70~85); the glucoraphanin, nine Peptide‑1, Palmitoyl Tripeptide‑5 and Trehalose were prepared as lyophilized powders. The composition of the present invention has remarkable whitening effect and good moisturizing effect through the synergistic effect of the compositions.

Description

technical field [0001] The invention relates to a skin care composition, in particular to a whitening skin care composition and a preparation method thereof. Background technique [0002] Melanin is a protein present in the basal layer of everyone's skin. The irradiation of ultraviolet rays will change the melanin to produce a substance that protects the skin, and then the melanin moves through the layers of cell metabolism to the epidermis of the skin, forming skin problems such as spots and uneven skin tone that we see. Whitening skin care products can help improve the condition of the skin, such as whitening products with niacinamide as the main ingredient, which can help the skin inhibit and regulate the transfer of melanin, and reduce the color spots that have formed. [0003] At present, the existing whitening agents include: arbutin, kojic acid, nicotinamide, etc. Although they have a whitening effect, they still have certain shortcomings. For example: arbutin has p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/64A61K8/60A61Q19/02
Inventor 龙洁陈建明苟小军陈封政张利兵
Owner CHENGDU UNIV
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