Preparation method of salidroside

Abstract

The invention discloses a preparation method of salidroside. The preparation method comprises removing rhizome soil of the salidroside, washing and drying; pulverizing the rhizome of the salidroside,adding a buffer solution and conducting enzymatic hydrolysis with biological enzyme to obtain an enzymatic hydrolysate; conducting enzyme deactivation, filtering, collecting a filtrate and conductingspraying and drying to obtain a salidroside crude extract; adding ethanol to the salidroside crude extract to prepare an ethanol extract; adding hydrochloric acid to the ethanol extract, stirring andheating to prepare a preliminary extraction solution; centrifuging the preliminary extraction solution, removing a precipitate, taking a supernatant and applying static pressure at room temperature toobtain a high pressure extraction solution; extracting the high pressure extraction solution repeatedly, adding a macroporous adsorption resin material, eluting with ethanol to obtain a purified solution; concentrating the purified solution, conducting evaporation crystallization and pulverizing to obtain a salidroside powder product. The compound enzyme is utilized to hydrolyze the salidroside,maximize the dissolution of the salidroside, ensure the extraction rate and improve the purity of the salidroside.

Description

Technical field

[0001] The present invention relates to the technical field of medicine extraction, in particular to a preparation method of salidroside. Background technique

[0002] Rhodiola (scientific name: Rhodiola rosea L.), aliases: Rhodiola rosea, Saul Mabul (Tibetan name), etc.; it is a perennial herb, 10-20 cm high. The roots are strong, conical, fleshy, brownish-yellow, with many fibrous roots on the neck of the root, short, thick, cylindrical, and many scale-like leaves arranged in tile-like shapes. It grows in the high and cold pollution-free zone at an altitude of 1800-2500 meters, and its growth environment is harsh, so it has strong vitality and special adaptability. It can be used for medicinal purposes. It can nourish qi and clear the lungs, nourish the mind and nourish the heart. It is a traditional Chinese medicine with a wide range of effects. It also has a great beauty effect, can be used as skin care products, and can also be eaten.

[0003] Natural plant ...