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DNA analysis method and DNA analysis apparatus using terahertz wave

A technology of deoxyribonucleic acid and analysis method, which is applied in the field of deoxyribonucleic acid analysis and deoxyribonucleic acid analysis devices using terahertz waves, and can solve problems such as low accuracy

Inactive Publication Date: 2019-07-16
UNIV OF SEOUL IND COOPERATION FOUND +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Despite these complex procedures, bisulfite conversion and array methods and ELISA-like methods have relatively low accuracy

Method used

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  • DNA analysis method and DNA analysis apparatus using terahertz wave
  • DNA analysis method and DNA analysis apparatus using terahertz wave
  • DNA analysis method and DNA analysis apparatus using terahertz wave

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Embodiment approach

[0045] Below, refer to Figure 7 A DNA analysis device for performing the DNA analysis method of the present invention described in detail will be described in detail.

[0046] Figure 7 It is a block diagram showing a DNA analysis device using a terahertz wave of the present invention. refer to Figure 7 The DNA analysis device of the present invention includes a control unit 100 , a terahertz wave irradiation unit 110 , a terahertz wave detection unit 120 , a peak detection unit 130 and a judgment unit 140 .

[0047] The control unit 100 generally controls the terahertz wave irradiation unit 110 , the terahertz wave detection unit 120 , the peak detection unit 130 , the determination unit 140 , and the DNA analyzer.

[0048] The terahertz wave irradiation unit 110 irradiates the methylated DNA with a terahertz wave. Preferably, the terahertz wave irradiation unit 110 irradiates the methylated DNA with the terahertz wave while changing the frequency of the terahertz wave....

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Abstract

The present invention relates to a DNA analysis method and a DNA analysis apparatus using a terahertz wave which are capable of accurately discriminating the type of cancer from DNA by using the terahertz wave. The DNA analysis method according to the present invention comprises the steps of: (a) irradiating methylated DNA with a terahertz wave; (b) detecting a terahertz wave reflected by the methylated DNA; (c) detecting a peak of the waveform of the terahertz wave detected in step (b); and (d) determining the type of cancer from the peak detected in step (c).

Description

technical field [0001] The present invention relates to a deoxyribonucleic acid analysis method and a deoxyribonucleic acid analysis device using a terahertz wave, and in particular to a deoxyribonucleic acid analysis method and a deoxyribose RNA analysis device. Background technique [0002] It is known that the methylation of deoxyribose nucleic acid is one of the most important mechanisms of cancer development. Methylation of deoxyribonucleic acid as a tumor marker is a phenomenon that occurs early in the development of cancer, is common in almost all cancers, and has inherent characteristics according to each organ of the human body. [0003] Figure 1a and Figure 1b It is a diagram briefly showing normal DNA and DNA in the case of cancer. Such as Figure 1a and Figure 1b As shown, if cancer occurs, it is different from nucleic acid. Therefore, the presence or absence of carcinogenicity can be confirmed by measuring the methylation of deoxyribonucleic acid. [00...

Claims

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Application Information

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IPC IPC(8): G01N21/3581C12Q1/6886
CPCC12Q1/68G01N21/3581C12Q2600/154C12Q1/6809G01N2021/3196G01N33/487C12Q2537/164C12Q2523/313C12Q2565/607C12Q2537/165
Inventor 孙周赫千和暎梁希真
Owner UNIV OF SEOUL IND COOPERATION FOUND
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