A kind of compound medicine for treating copd and preparation method thereof

Abstract

The invention relates to a compound medicine for treating COPD and a preparation method thereof. The compound medicine comprises palmatine or a pharmaceutically acceptable salt thereof, a β2-receptor agonist and a pharmaceutically acceptable carrier. By combining the β2 receptor agonist with palmatine or a pharmaceutically acceptable salt thereof, the drug effect of the β2 receptor agonist can be effectively enhanced, the required dosage of the β2 receptor agonist can be reduced, and it is beneficial to reduce the The side effects of β2-receptor agonists in the treatment of COPD, enhance the tolerance of patients to β2-receptor agonists, and expand the scope of applicable objects of β2-receptor agonists.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to a compound medicine for treating COPD and a preparation method thereof. Background technique [0002] Chronic obstructive pulmonary disease (COPD), referred to as COPD, is a chronic lung disease characterized by not fully reversible airflow limitation, mainly manifested as recurrent cough, sputum production, shortness of breath, and exercise tolerance The early signs are not obvious, but as the disease progresses, the patient will experience gradually worsening breathing difficulties. Affected by multiple factors such as smoking, air pollution, lung infection, and genetics, the incidence of COPD in my country is increasing year by year. Epidemiological studies have shown that the incidence of COPD among people over 40 years old in my country from 2002 to 2004 It is about 8.2%, and according to the survey results of the "China Lung Health Research" in April 2018, the incidence...

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