Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of citral in inhibiting growth of multi-drug resistant enterobacter sinensis

A technology for treating Enterobacter horii and Enterobacter horii is applied in the application field of citral in inhibiting the growth of multi-drug resistant Enterobacter horii, and can solve the problems such as research reports on Enterobacter horii that have not yet been found, and achieves a solution to the problem. The problem of drug-resistant infection, the value of widespread application, and the effect of reducing the fatality rate

Active Publication Date: 2019-09-17
SHAANXI UNIV OF SCI & TECH
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, no research reports on the inhibition of Enterobacter hallii by citral have been found

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of citral in inhibiting growth of multi-drug resistant enterobacter sinensis
  • Application of citral in inhibiting growth of multi-drug resistant enterobacter sinensis
  • Application of citral in inhibiting growth of multi-drug resistant enterobacter sinensis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0015] The present invention will be described in further detail below in conjunction with the examples. The embodiments are only used to explain the present invention, not to limit the protection scope of the present invention.

[0016] 1. Drug susceptibility test of human Enterobacter hallii

[0017] In the present invention, two strains of human-derived Enterobacter hallii are used as starting strains (strain samples are taken from the General Hospital of the Chinese People's Liberation Army), and piperacillin, gentamicin, bromogmentine, imipenem, and ofloxacin are selected. , nitrofurantoin, ceftaquine, nalidixic acid 8 kinds of antibiotic susceptibility test strips for drug susceptibility test.

[0018] The pure colonies picked and cultured for 18-24 hours were evenly dissolved in 2-5 mL sterile saline, and the turbidity was adjusted to be equal to that of a 0.5 McFarland turbidimetric tube. Aseptically draw 50-200 μL of bacterial solution, spread evenly on the plate, a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
concentrationaaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses the application of citral in inhibiting the growth of multi-drug resistant enterobacter sinensis. According to the fact that citral has a good in-vitro killing effect on the multi-drug resistant enterobacter sinensis resistant to piperacillin, augmentin, imipenem, ofloxacin, nitrofurantoin, cefotaxime and nalidixic acid, can inhibit the growth of the multi-drug resistant enterobacter sinensis, and has a minimum bactericidal concentration of 2.8 mg / mL and a minimum inhibitory concentration of 2.4 mg / mL, the inhibitory effect of citral on the multi-drug resistant enterobacter sinensis is proposed, and citral has wide application value in the field of medicine.

Description

technical field [0001] The invention relates to the research, development and application of citral, an active ingredient of traditional Chinese medicine, as a bacterial inhibitor, in particular to the application of citral in inhibiting the growth of multidrug-resistant Enterobacter hallii. Background technique [0002] Enterobacter hormaechei (Enterobacter hormaechei) is a Gram-negative bacterium, facultatively anaerobic, easy to grow on ordinary medium, and exists in the intestinal tract of humans and animals. Enterobacter hallii can cause infection in animals and humans under certain conditions. It is an opportunistic pathogenic bacterium that can be isolated from infected animals or animal wounds. Cases caused by its infection include stroke (Ming Desong, Zhu Yan, Xie Zunjin. Study on drug resistance and drug resistance mechanism of sputum Enterobacter Halemannii in stroke patients[J]. Chinese Journal of Hospital Infection, 2011, 21(05): 1025-1026.), Bacteremia in prema...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/11A61P31/04
CPCA61K31/11A61P31/04
Inventor 钱卫东沈兰芳王婷杨敏刘淼李鑫辰王文静付玉婷
Owner SHAANXI UNIV OF SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com